Lysophospholipid Activation of G Protein-Coupled Receptors

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

2003 • 7,170 citations

Rho GTPases in cell biology

2002 • 4,662 citations

Seven-transmembrane receptors

2002 • 2,571 citations

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

Pharmacologic management of neuropathic pain: Evidence-based recommendations

2007 • 2,078 citations

Sphingosine-1-phosphate: an enigmatic signalling lipid

2003 • 2,022 citations

Transduction of Receptor Signals by ß-Arrestins

2005 • 1,656 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

G Protein Pathways

2002 • 1,222 citations

Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

2000 • 1,138 citations

The emerging role of lysophosphatidic acid in cancer

2003 • 1,086 citations

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

1998 • 1,003 citations

Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate

2007 • 861 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients

2005 • 772 citations

Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation

2001 • 772 citations

Lysophospholipid Receptors: Signaling and Biology

2004 • 752 citations

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

1996 • 727 citations

Essential Role for Sphingosine Kinases in Neural and Vascular Development

2005 • 719 citations

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

2005 • 681 citations

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

2000 • 654 citations

The bioactive phospholipid lysophosphatidic acid is released from activated platelets

1993 • 653 citations

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation.

1991 • 627 citations

Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate

2004 • 619 citations

HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3

2004 • 611 citations

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine -1-phosphate therapy

2000 • 581 citations

HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3

2004 • 578 citations

Finding a way out: lymphocyte egress from lymphoid organs

2007 • 573 citations

The ins and outs of lysophosphatidic acid signaling

2004 • 550 citations

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist

2002 • 545 citations

LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing

2005 • 541 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

2006 • 528 citations

Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development

2006 • 524 citations

Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology

2007 • 524 citations

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

2004 • 503 citations

Requirement for the lp _A1 lysophosphatidic acid receptor gene in normal suckling behavior

2000 • 468 citations

GPR92 as a New G12/13- and Gq-coupled Lysophosphatidic Acid Receptor That Increases cAMP, LPA5

2006 • 462 citations

International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

2002 • 462 citations

Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid

2006 • 451 citations

Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

2004 • 439 citations

Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration

2004 • 436 citations

Role of the Sphingosine-1-Phosphate Receptor EDG-1 in PDGF-Induced Cell Motility

2001 • 421 citations

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions

1999 • 411 citations

Lysophosphatidic Acid Receptors

2000 • 404 citations

Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway

1998 • 404 citations

The Sphingosine-1-phosphate Receptors S1P1, S1P2, and S1P3 Function Coordinately during Embryonic Angiogenesis

2004 • 402 citations

A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development

2000 • 401 citations

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo

2006 • 400 citations

Immunosuppressive and Anti-angiogenic Sphingosine 1-Phosphate Receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor

2007 • 394 citations

High-Density Lipoproteins and Their Constituent, Sphingosine-1-Phosphate, Directly Protect the Heart Against Ischemia/Reperfusion Injury In Vivo via the S1P ₃ Lysophospholipid Receptor

2006 • 394 citations

Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors

2003 • 392 citations

Commuting the death sentence: how oocytes strive to survive

2001 • 383 citations

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation

2003 • 373 citations

Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism

2006 • 367 citations

Erythrocytes store and release sphingosine 1‐phosphate in blood

2007 • 355 citations

Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

2000 • 328 citations

Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival

2005 • 325 citations

Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8

2000 • 323 citations

Lysophospholipid Receptors

2001 • 319 citations

Characterization of lpa₂ (Edg4) and lpa₁/lpa₂ (Edg2/Edg4) Lysophosphatidic Acid Receptor Knockout Mice: Signaling Deficits without Obvious Phenotypic Abnormality Attributable to lpa₂

2002 • 315 citations

Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase

2000 • 315 citations

Transactivation of Sphingosine-1–Phosphate Receptors by FcεRI Triggering Is Required for Normal Mast Cell Degranulation and Chemotaxis

2004 • 313 citations

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

1995 • 306 citations

Signalling and crosstalk of Rho GTPases in mediating axon guidance

2002 • 299 citations

Mechanisms of lysophosphatidic acid production

2004 • 293 citations

A NOVEL IMMUNOSUPPRESSANT, FTY720, WITH A UNIQUE MECHANISM OF ACTION, INDUCES LONG-TERM GRAFT ACCEPTANCE IN RAT AND DOG ALLOTRANSPLANTATION1

1996 • 291 citations

Antagonism of Sphingosine-1-Phosphate Receptors by FTY720 Inhibits Angiogenesis and Tumor Vascularization

2006 • 288 citations

Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment

2003 • 281 citations

Lysophospholipid G Protein-coupled Receptors

2004 • 281 citations

A single receptor encoded by vzg-1 / lp _A1 / edg- 2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

1998 • 280 citations

Regulation of sphingosine 1‐phosphate‐induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P₁receptor, PI3 kinase, Tiam1/Rac1, and α‐actinin

2005 • 273 citations

Selective Loss of Sphingosine 1-Phosphate Signaling with No Obvious Phenotypic Abnormality in Mice Lacking Its G Protein-coupled Receptor, LPB3/EDG-3

2001 • 271 citations

Sphingosine 1-Phosphate Analogs as Receptor Antagonists

2004 • 267 citations

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720

2005 • 263 citations

Inhibitory and Stimulatory Regulation of Rac and Cell Motility by the G_12/13-Rho and G_i Pathways Integrated Downstream of a Single G Protein-Coupled Sphingosine-1-Phosphate Receptor Isoform

2003 • 259 citations

Point-Counterpoint of Sphingosine 1-Phosphate Metabolism

2004 • 251 citations

Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding

2003 • 249 citations

Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids¹

1997 • 247 citations

Marked Perinatal Lethality and Cellular Signaling Deficits in Mice Null for the Two Sphingosine 1-Phosphate (S1P) Receptors, S1P2/LPB2/EDG-5 and S1P3/LPB3/EDG-3

2002 • 241 citations

Emerging medicinal roles for lysophospholipid signaling

2006 • 240 citations

Characterization of plasma unsaturated lysophosphatidylcholines in human and rat

1999 • 233 citations

Activation‐regulated expression and chemotactic function of sphingosine 1‐phosphate receptors in mouse splenic T cells

2002 • 229 citations

Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?

2002 • 228 citations

Lysophospholipid receptor nomenclature

2002 • 225 citations

Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice

2004 • 221 citations

Cell surface receptors in lysophospholipid signaling

2004 • 221 citations

Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1

2006 • 220 citations

Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax

1999 • 219 citations

FTY720, A Novel Immunomodulator: Efficacy and Safety Results from the First Phase 2A Study in de novo Renal Transplantation

2004 • 216 citations

Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720

2005 • 211 citations

Functional Comparisons of the Lysophosphatidic Acid Receptors, LP_A1/VZG-1/EDG-2, LP_A2/EDG-4, and LP_A3/EDG-7 in Neuronal Cell Lines Using a Retrovirus Expression System

2000 • 206 citations

The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases

2006 • 205 citations

Common Signaling Pathways Link Activation of Murine PAR-1, LPA, and S1P Receptors to Proliferation of Astrocytes

2003 • 204 citations

Essential Roles of Sphingosine 1-Phosphate/S1P1 Receptor Axis in the Migration of Neural Stem Cells Toward a Site of Spinal Cord Injury

2006 • 199 citations

Sphingosine‐1‐phosphate induces proliferation and morphological changes of neural progenitor cells

2004 • 195 citations

G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

2004 • 193 citations

Deafness and Stria Vascularis Defects in S1P2 Receptor-null Mice

2007 • 191 citations

Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models.

2002 • 191 citations

A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells

2005 • 188 citations

PDGF signaling specificity is mediated through multiple immediate early genes

2006 • 184 citations

An essential role for the H218/AGR16/Edg‐5/LP_B2 sphingosine 1‐phosphate receptor in neuronal excitability

2001 • 182 citations

Connexin Hemichannels and Gap Junction Channels Are Differentially Influenced by Lipopolysaccharide and Basic Fibroblast Growth Factor

2006 • 181 citations

Lysophospholipids and their G protein-coupled receptors in inflammation and immunity

2002 • 179 citations

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

2000 • 174 citations

Role of RhoA and Rho Kinase in Lysophosphatidic Acid–Induced Endothelial Barrier Dysfunction

2000 • 172 citations

Lysophosphatidic Acid (LPA) Is a Novel Extracellular Regulator of Cortical Neuroblast Morphology

2000 • 170 citations

Regulation of Schwann Cell Morphology and Adhesion by Receptor-Mediated Lysophosphatidic Acid Signaling

2001 • 169 citations

The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning

2003 • 166 citations

Effects of synthetic and natural lysophosphatidic acids on the arterial blood pressure of different animal species

1978 • 164 citations

Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate

2000 • 155 citations

Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate

2002 • 154 citations

Regulation of Astrocyte Morphology by RhoA and Lysophosphatidic Acid

1998 • 153 citations

Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors.

2001 • 153 citations

Identification of a lysophosphatidylserine receptor on mast cells

2006 • 152 citations

Simultaneous Quantitative Analysis of Sphingoid Base 1-Phosphates in Biological Samples by o-Phthalaldehyde Precolumn Derivatization after Dephosphorylation with Alkaline Phosphatase

2002 • 149 citations

Inhibition of Th1- and Th2-Mediated Airway Inflammation by the Sphingosine 1-Phosphate Receptor Agonist FTY720

2003 • 145 citations

Absence of LPA1 Signaling Results in Defective Cortical Development

2007 • 142 citations

Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors

2004 • 137 citations

Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography–tandem mass spectrometry

2004 • 136 citations

Lysophosphatidic Acid-induced Mitogenesis Is Regulated by Lipid Phosphate Phosphatases and Is Edg-receptor Independent

2001 • 136 citations

Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction.

1999 • 133 citations

Comparison of Sphingosine 1-Phosphate–Induced Intracellular Signaling Pathways in Vascular Smooth Muscles

2002 • 128 citations

LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease

2003 • 125 citations

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

2003 • 124 citations

A Monoselective Sphingosine-1-Phosphate Receptor-1 Agonist Prevents Allograft Rejection in a Stringent Rat Heart Transplantation Model

2006 • 122 citations

Immunomodulator FTY720 Induces eNOS-Dependent Arterial Vasodilatation via the Lysophospholipid Receptor S1P ₃

2005 • 122 citations

A putative new growth factor in ascitic fluid from ovarian cancer patients: identification, characterization, and mechanism of action.

1988 • 121 citations

Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.

2002 • 120 citations

Lysophosphatidic acid alters cerebrovascular reactivity in piglets

1995 • 120 citations

KRP-203, a Novel Synthetic Immunosuppressant, Prolongs Graft Survival and Attenuates Chronic Rejection in Rat Skin and Heart Allografts

2005 • 119 citations

Sphingosine-1-Phosphate Prevents Tumor Necrosis Factor-α–Mediated Monocyte Adhesion to Aortic Endothelium in Mice

2005 • 118 citations

Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1

2003 • 116 citations

The roles of sphingosine-1-phosphate in asthma

2002 • 113 citations

Sphingosine 1-Phosphate (S1P) Signaling Is Required for Maintenance of Hair Cells Mainly via Activation of S1P₂

2007 • 112 citations

Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice1

2007 • 112 citations

The Sphingosine‐1‐Phosphate Receptor Agonist FTY720 Modulates Dendritic Cell Trafficking In Vivo

2005 • 111 citations

Quantitative Measurement of Sphingosine 1-Phosphate by Radioreceptor-Binding Assay

2000 • 108 citations

Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p₁ in neurogenesis and s1p_1–3 in angiogenesis

2002 • 105 citations

High-Density Lipoprotein Stimulates Myocardial Perfusion In Vivo

2004 • 103 citations

Lysophosphatidic Acid Receptor-Selective Effects on Jurkat T Cell Migration Through a Matrigel Model Basement Membrane

2001 • 96 citations

GPCR Agonists and Antagonists in the Clinic

2005 • 94 citations

Cutting Edge: Differential Constitutive Expression of Functional Receptors for Lysophosphatidic Acid by Human Blood Lymphocytes

2000 • 91 citations

Developmental expression analysis of murine autotaxin (ATX)

1999 • 88 citations

Effects of LPA and S1P on the Nervous System and Implications for Their Involvement in Disease

2006 • 88 citations

Sphingosine‐1‐phosphate modulates growth and adhesion of ovarian cancer cells

1999 • 87 citations

Characterization of the Human and Mouse Sphingosine 1-Phosphate Receptor, S1P₅ (Edg-8): Structure−Activity Relationship of Sphingosine1-Phosphate Receptors

2001 • 86 citations

The S1P2 sphingosine 1-phosphate receptor is essential for auditory and vestibular function

2006 • 85 citations

Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets?

1982 • 84 citations

Quantification, characterization and fatty acid composition of lysophosphatidic acid in different rat tissues

1989 • 83 citations

Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma

2005 • 82 citations

Lysophosphatidic acid: mitogen and motility factor

2003 • 82 citations

Lysophosphatidic Acid Stimulates Neurotransmitter-Like Conductance Changes that Precede GABA and l-Glutamate in Early, Presumptive Cortical Neuroblasts

1999 • 80 citations

Lysophospholipid Receptors as Potential Drug Targets in Tissue Transplantation and Autoimmune Diseases

2005 • 79 citations

Altered expression and functional profile of lysophosphatidic acid receptors in mitogen‐activated human blood T lymphocytes

2000 • 78 citations

The mouse lpA3/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern

2001 • 78 citations

S1P inhibits gap junctions in astrocytes: involvement of G_i and Rho GTPase/ROCK

2006 • 77 citations

Lysophosphatidic acid stimulates astrocyte proliferation through LPA1

2007 • 75 citations

Lysophosphatidic acid stimulates neuronal differentiation of cortical neuroblasts through the LPA1–Gi/o pathway

2006 • 74 citations

Sphingosine Kinase from Swiss 3T3 Fibroblasts: A Convenient Assay for the Measurement of Intracellular Levels of Free Sphingoid Bases

1994 • 73 citations

Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells

2005 • 73 citations

Selective blockade of lysophosphatidic acid LPA₃receptors reduces murine renal ischemia-reperfusion injury

2003 • 73 citations

Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade

1994 • 72 citations

Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats

2000 • 71 citations

Antihypertensive effect of an isolated phospholipid

1968 • 65 citations

Lysophospholipid mediators of immunity and neoplasia

2002 • 65 citations

Anti-Apoptotic Effect of Sphingosine-1-Phosphate and Platelet-Derived Growth Factor in Human Embryonic Stem Cells

2007 • 63 citations

Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal

2007 • 62 citations

Effects of FTY720, a Novel Immunosuppressant, on Experimental Autoimmune Uveoretinitis in Rats

2000 • 61 citations

Signaling Mechanisms Responsible for Lysophosphatidic Acid-induced Urokinase Plasminogen Activator Expression in Ovarian Cancer Cells

2005 • 60 citations

Metabolism of Sphingosine Bases, XIII. Enzymatic Synthesis of 1-Phosphate Esters of 4t-Sphingenine (Sphingosine), Sphinganine (Dihydrosphingosine), 4-Hydroxysphinganine (Phytosphingosine) and 3-Dehydrosphinganine by Erythrocytes

1970 • 57 citations

Synthesis of para-Alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists

2003 • 53 citations

Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus

2006 • 53 citations

Characterization of plasma unsaturated lysophosphatidylcholines in human and rat

2000 • 52 citations

Use of Sphingosine-1-Phosphate 1 Receptor Agonist, KRP-203, in Combination with a Subtherapeutic Dose of Cyclosporine A for Rat Renal Transplantation

2006 • 52 citations

Of Spiders and Crabs: The Emergence of Lysophospholipids and Their Metabolic Pathways as Targets for Therapy in Cancer

2006 • 52 citations

Chemical Tools to Investigate Sphingolipid Metabolism and Functions

2007 • 51 citations

Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells

2006 • 49 citations

Potential role of lysophosphatidic acid in hypertension and atherosclerosis.

2003 • 48 citations

Distribution of sphingosine 1‐phosphate, a bioactive sphingolipid, in rat tissues

1997 • 48 citations

Identifying Specific Conformations by Using a Carbohydrate Scaffold: Discovery of Subtype‐Selective LPA‐Receptor Agonists and an Antagonist

2004 • 47 citations

Mechanisms of cardioprotection by lysophospholipids

2004 • 47 citations

Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists

2004 • 42 citations

Roles of LPA3 and COX-2 in implantation

2005 • 39 citations

Structure/Activity Relationships in Lysophosphatidic Acid: The 2-Hydroxyl Moiety

1997 • 33 citations

HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate

2007 • 33 citations

Receptor tyrosine kinase-G-protein coupled receptor complex signaling in mammalian cells

2007 • 27 citations

Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720

1999 • 22 citations

The role of high-density lipoprotein cholesterol in atherothrombosis.

2006 • 22 citations

Lysophosphatidic Acid and Sphingosine 1‐Phosphate: Two Lipid Villains Provoking Cardiovascular Diseases?

2000 • 22 citations

A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor.

2004 • 21 citations

Sphingosine 1-Phosphate Inhibits Migration of RBL-2H3 Cells via S1P2: Cross-Talk between Platelets and Mast Cells

2004 • 20 citations

Prevention of Experimentally Induced Autoimmune Type I Diabetes in Rats by the New Immunosuppressive Reagent FTY720

1998 • 19 citations

Structural characteristics of lysophosphatidic acid biological targets

2005 • 16 citations

The First Cloned and Identified Lysophospholipid (LP) Receptor Gene, VZG-1: Implications for Related Receptors and the Nervous System

1999 • 5 citations

Potential Therapeutic Roles Of Lysophospholipid Signaling In Autoimmune-Related Disease

2007 • 4 citations