Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720

CYCLOSPORIN A IN PATIENTS RECEIVING RENAL ALLOGRAFTS FROM CADAVER DONORS

1978 • 1,010 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

1998 • 586 citations

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

1995 • 306 citations

A NOVEL IMMUNOSUPPRESSANT, FTY720, WITH A UNIQUE MECHANISM OF ACTION, INDUCES LONG-TERM GRAFT ACCEPTANCE IN RAT AND DOG ALLOTRANSPLANTATION1

1996 • 291 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. II. FTY720 Prolongs Skin Allograft Survival by Decreasing T Cell Infiltration into Grafts But Not Cytokine Production In Vivo

1998 • 263 citations

NEPHROTOXICITY FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION

1994 • 198 citations

NEPHROTOXICITY FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION

1994 • 194 citations

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology

1993 • 181 citations

Spontaneous thyroiditis in thymectomized and irradiated Wistar rats.

1973 • 179 citations

A new immunosuppressant, FTY720, induces bcl‐2‐associated apoptotic cell death in human lymphocytes

1996 • 121 citations

Thyroiditis in T cell-depleted rats. Influence of strain, radiation dose, adjuvants and antilymphocyte serum.

1975 • 118 citations

Simple compounds, 2-alkyl-2-amino-1,3-propanediols have potent immunosuppressive activity

1995 • 102 citations

The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720

1997 • 68 citations

The Influence of Methimazole on Thyroglobulin-Induced Autoimmune Thyroiditis in the Rat*

1983 • 67 citations

Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY 720, in rat small bowel transplantation

1997 • 50 citations

Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats

1996 • 48 citations

The influence of cyclosporin a on experimental autoimmune thyroid disease in the rat

1983 • 35 citations

The influence of cyclosporin A on the induction of experimental autoimmune thyroid disease in the PVG/c rat.

1985 • 21 citations

Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production

1993 • 21 citations

Transplant International

1996 • 9 citations