Sphingosine 1-Phosphate Inhibits Migration of RBL-2H3 Cells via S1P2: Cross-Talk between Platelets and Mast Cells

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

1999 • 999 citations

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.

1992 • 683 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Sphingosine 1-Phosphate, a Key Cell Signaling Molecule

2002 • 551 citations

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

1997 • 442 citations

Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway

1998 • 404 citations

Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

2000 • 328 citations

Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8

2000 • 323 citations

Sphingosine 1‐phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma

2001 • 318 citations

Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors

2002 • 309 citations

Akt-Mediated Phosphorylation of the G Protein-Coupled Receptor EDG-1 Is Required for Endothelial Cell Chemotaxis

2001 • 284 citations

EDG6, a Novel G-Protein-Coupled Receptor Related to Receptors for Bioactive Lysophospholipids, Is Specifically Expressed in Lymphoid Tissue

1998 • 231 citations

Lysophospholipid receptor nomenclature

2002 • 225 citations

Signal Transduction by the High-Affinity Immunoglobulin E Receptor FcεRI: Coupling Form to Function

2001 • 206 citations

Platelets and inflammation: Role of platelet-derived growth factor, adhesion molecules and histamine

1997 • 201 citations

Sphingosine 1-Phosphate Induces Platelet Activation through an Extracellular Action and Shares a Platelet Surface Receptor with Lysophosphatidic Acid

1997 • 200 citations

Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist

2002 • 191 citations

Sphingosine 1-phosphate: synthesis and release

2001 • 187 citations

Sphingosine 1-Phosphate-induced Cell Rounding and Neurite Retraction Are Mediated by the G Protein-coupled Receptor H218

1999 • 183 citations

The Balance between Sphingosine and Sphingosine-1-Phosphate Is Decisive for Mast Cell Activation after Fc∈ Receptor I Triggering

1999 • 175 citations

Subtype-specific differential regulation of Rho family G proteins and cell migration by the Edg family sphingosine-1-phosphate receptors

2002 • 172 citations

Dichotomy of Ca2+ Signals Triggered by Different Phospholipid Pathways in Antigen Stimulation of Human Mast Cells

2002 • 164 citations

Platelet Production in the Pulmonary Capillary Bed

2000 • 141 citations

Functional Expression of the High Affinity Receptor for IgE (FcɛRI) in Human Platelets and Its’ Intracellular Expression in Human Megakaryocytes

1999 • 124 citations

Platelets as inflammatory cells

1989 • 123 citations

The roles of sphingosine-1-phosphate in asthma

2002 • 113 citations

Nerve Growth Factor Activates Mast Cells Through the Collaborative Interaction with Lysophosphatidylserine Expressed on the Membrane Surface of Activated Platelets

2002 • 92 citations

Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5

2003 • 90 citations

Platelet Activation in the Lung after Antigen Challenge in a Model of Allergic Asthma

1992 • 71 citations

Collagen, convulxin and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets: evidence for the involvement of Src-family kinases

2000 • 69 citations

The evidence of platelet activation in bronchial asthma

1993 • 63 citations

Elevation of the plasma level of RANTES during asthma attacks

1997 • 56 citations

Activation of Platelets in Bronchial Asthma

1998 • 55 citations

Platelets in Bronchoalveolar Lavage from Asthmatic Patients and Allergic Rabbits with Allergen-Induced Late Phase Responses

1987 • 49 citations

Essential Roles of Lyn in Fibronectin-Mediated Filamentous Actin Assembly and Cell Motility in Mast Cells

1998 • 48 citations

Eotaxin induces migration of RBL-2H3 mast cells via a Rac-ERK-dependent pathway

2002 • 36 citations

Endocytosis, storage, and release of IgE by human platelets: Differences in patients with type I allergy and nonatopic subjects

1997 • 35 citations

Thrombin Primes Responsiveness of Selective Chemoattractant Receptors at a Site Distal to G Protein Activation

1996 • 35 citations

Sphingosine‐1‐phosphate Inhibits Haptotactic Motility by Overproduction of Focal Adhesion Sites in B16 Melanoma Cells through EDG‐Induced Activation of Rho

2000 • 30 citations

Evidence for Platelet Activation in Allergic Asthma

1987 • 23 citations

Potential Role of EDG Receptors and Lysophospholipids as their Endogenous Ligands in the Respiratory Tract

2000 • 21 citations

Effect of thromboxane A2 (TXA2) synthase inhibitor and TXA2 receptor antagonist alone and in combination on antigen-induced bronchoconstriction in guinea pigs

2001 • 13 citations