The role of high-density lipoprotein cholesterol in atherothrombosis.

Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

1993 • 28,274 citations

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial

2002 • 15,184 citations

Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women

1998 • 6,250 citations

Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia

1987 • 3,889 citations

Gemfibrozil for the Secondary Prevention of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein Cholesterol

1999 • 3,464 citations

High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.

1989 • 3,169 citations

C-Reactive Protein Levels and Outcomes after Statin Therapy

2005 • 2,249 citations

Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease

2001 • 1,999 citations

Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes

2003 • 1,693 citations

Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR**STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)

2003 • 1,382 citations

Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease

2005 • 1,316 citations

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

1998 • 1,078 citations

Selective Estrogen-Receptor Modulators — Mechanisms of Action and Application to Clinical Practice

2003 • 942 citations

Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2

2004 • 903 citations

National Cholesterol Education Program. Second Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II).

1994 • 809 citations

Effects of an Inhibitor of Cholesteryl Ester Transfer Protein on HDL Cholesterol

2004 • 779 citations

Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit.

1990 • 767 citations

Inhibition of Intestinal Cholesterol Absorption by Ezetimibe in Humans

2002 • 664 citations

HDL Cholesterol and Protective Factors in Atherosclerosis

2004 • 629 citations

Raloxifene and Cardiovascular Events in Osteoporotic Postmenopausal Women

2002 • 584 citations

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits

2000 • 538 citations

Human Serum Paraoxonases (PON1) Q and R Selectively Decrease Lipid Peroxides in Human Coronary and Carotid Atherosclerotic Lesions

2000 • 464 citations

Efficacy and Safety of a Novel Cholesteryl Ester Transfer Protein Inhibitor, JTT-705, in Humans

2002 • 459 citations

High-Density Lipoprotein Restores Endothelial Function in Hypercholesterolemic Men

2002 • 448 citations

Decreased Atherosclerotic Lesion Formation in Human Serum Paraoxonase Transgenic Mice

2002 • 446 citations

HDL and the Inflammatory Response Induced by LDL-Derived Oxidized Phospholipids

2001 • 441 citations

Low Paraoxonase Activity Predicts Coronary Events in the Caerphilly Prospective Study

2003 • 424 citations

Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds

2005 • 421 citations

High-Dose Recombinant Apolipoprotein A-I _Milano Mobilizes Tissue Cholesterol and Rapidly Reduces Plaque Lipid and Macrophage Content in Apolipoprotein E–Deficient Mice

2001 • 381 citations

RAPID COMMUNICATION: Inhibitory Effect of Pioglitazone on Carotid Arterial Wall Thickness in Type 2 Diabetes

2001 • 354 citations

Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids

2001 • 351 citations

Cardiovascular Status of Carriers of the Apolipoprotein A-I _Milano Mutant

2001 • 320 citations

Vaccine-Induced Antibodies Inhibit CETP Activity In Vivo and Reduce Aortic Lesions in a Rabbit Model of Atherosclerosis

2000 • 313 citations

Alcohol Consumption Raises HDL Cholesterol Levels by Increasing the Transport Rate of Apolipoproteins A-I and A-II

2000 • 295 citations

A Meta-analysis Comparing the Effect of Thiazolidinediones on Cardiovascular Risk Factors

2004 • 293 citations

Restoration of Endothelial Function by Increasing High-Density Lipoprotein in Subjects With Isolated Low High-Density Lipoprotein

2003 • 291 citations

Nicotinic Acid as Therapy for Dyslipidemia in Non—Insulin-Dependent Diabetes Mellitus

1990 • 278 citations

Genetic Cholesteryl Ester Transfer Protein Deficiency Is Extremely Frequent in the Omagari Area of Japan

1997 • 269 citations

Preventative Effects of Rosiglitazone on Restenosis After Coronary Stent Implantation in Patients With Type 2 Diabetes

2004 • 249 citations

Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model.

1996 • 249 citations

Wine and Your Heart

2001 • 246 citations

Effect of Antisense Oligonucleotides against Cholesteryl Ester Transfer Protein on the Development of Atherosclerosis in Cholesterol-fed Rabbits

1998 • 244 citations

Elevation of Plasma High-Density Lipoprotein Concentration Reduces Interleukin-1–Induced Expression of E-Selectin in an In Vivo Model of Acute Inflammation

2001 • 238 citations

High Density Lipoproteins (HDL) Interrupt the Sphingosine Kinase Signaling Pathway

1999 • 235 citations

A Randomized Trial of a Strategy for Increasing High-Density Lipoprotein Cholesterol Levels: Effects on Progression of Coronary Heart Disease and Clinical Events

2005 • 234 citations

Benefits of niacin by glycemic status in patients with healed myocardial infarction (from the Coronary Drug Project)

2005 • 229 citations

Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells

2004 • 222 citations

High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C

1999 • 220 citations

Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Inhibits the Development of Atherosclerosis in ApoE Knockout Mice

2001 • 217 citations

Differential Regulation of Lipoprotein Kinetics by Atorvastatin and Fenofibrate in Subjects With the Metabolic Syndrome

2003 • 216 citations

Niacin Decreases Removal of High-Density Lipoprotein Apolipoprotein A-I But Not Cholesterol Ester by Hep G2 Cells

1997 • 197 citations

The effects of rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, on markers of endothelial cell activation, C-reactive protein, and fibrinogen levels in non-diabetic coronary artery disease patients

2003 • 196 citations

Recombinant Apolipoprotein A-I _Milano Infusion Into Rabbit Carotid Artery Rapidly Removes Lipid From Fatty Streaks

2002 • 195 citations

Scavenger receptor Bl and cholesterol trafficking

1999 • 178 citations

Regulation of low-density lipoprotein receptors: implications for pathogenesis and therapy of hypercholesterolemia and atherosclerosis.

1987 • 177 citations

Platelet-activating Factor Acetylhydrolase, and Not Paraoxonase-1, Is the Oxidized Phospholipid Hydrolase of High Density Lipoprotein Particles

2003 • 175 citations

Promotion and Prescribing of Hormone Therapy After Report of Harm by the Women’s Health Initiative

2004 • 174 citations

Design and methods of the Raloxifene Use for The Heart (RUTH) study

2001 • 172 citations

Pathogenetic concepts of acute coronary syndromes

2003 • 168 citations

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

2002 • 161 citations

Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells

2002 • 139 citations

Inhibition of Arterial Thrombus Formation by ApoA1 Milano

1999 • 136 citations

Oxidized LDL and Atherogenesis^a

1999 • 136 citations

Raloxifene Inhibits Aortic Accumulation of Cholesterol in Ovariectomized, Cholesterol-Fed Rabbits

1997 • 135 citations

Evidence that high-density lipoprotein cholesterol is an independent predictor of acute platelet-dependent thrombus formation

1999 • 133 citations

Activation of fibrinolysis by apolipoproteins of high density lipoproteins in man

1985 • 124 citations

AIMilano apoprotein identification of the complete kindred and evidence of a dominant genetic transmission.

1985 • 119 citations

Alcohol consumption stimulates early steps in reverse cholesterol transport

2001 • 115 citations

Tamoxifen and toremifene lower serum cholesterol by inhibition of delta 8-cholesterol conversion to lathosterol in women with breast cancer.

1995 • 108 citations

Atherogenic Lipoproteins Support Assembly of the Prothrombinase Complex and Thrombin Generation: Modulation by Oxidation and Vitamin E

1998 • 106 citations

Characterization of plasma lipoproteins in patients heterozygous for human plasma cholesteryl ester transfer protein (CETP) deficiency: Plasma CETP regulates high-density lipoprotein concentration and composition

1991 • 103 citations

HDL and apolipoprotein A-I protect erythrocytes against the generation of procoagulant activity.

1994 • 89 citations

Anticoagulant activity of tissue factor pathway inhibitor in human plasma is preferentially associated with dense subspecies of LDL and HDL and with Lp(a).

1993 • 84 citations

A Comparison of the Effects of Raloxifene and Conjugated Equine Estrogen on Bone and Lipids in Healthy Postmenopausal Women

2004 • 82 citations

The effects of cholestyramine on high density lipoprotein metabolism

1979 • 82 citations

Mortality from ischaemic heart disease among patients using anticonvulsive drugs: a case-control study.

1985 • 78 citations

Intramural Delivery of Recombinant Apolipoprotein A-I _Milano /Phospholipid Complex (ETC-216) Inhibits In-Stent Stenosis in Porcine Coronary Arteries

2003 • 73 citations

Two novel missense mutations in the CETP gene in Japanese hyperalphalipoproteinemic subjects: High-throughput assay by Invader® assay

2002 • 68 citations

Effects of a moderate dose of alcohol on blood lipids and lipoproteins postprandially and in the fasting state.

1990 • 61 citations

Effect of Overexpression of Human Apo A-I in C57BL/6 and C57BL/6 Apo E–Deficient Mice on 2 Lipoprotein-Associated Enzymes, Platelet-Activating Factor Acetylhydrolase and Paraoxonase

2000 • 61 citations

Alcohol and high-density-lipoprotein cholesterol:a randomized controlled trial

1986 • 56 citations

Apolipoprotein A-I_Milanoand 1-Palmitoyl-2-oleoyl Phosphatidylcholine Complex (ETC-216) Protects the in Vivo Rabbit Heart from Regional Ischemia-Reperfusion Injury

2004 • 56 citations

Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins

2001 • 53 citations

Action of Ciprofibrate in Type IIB Hyperlipoproteinemia: Modulation of the Atherogenic Lipoprotein Phenotype and Stimulation of High-Density Lipoprotein-Mediated Cellular Cholesterol Efflux

2003 • 51 citations

Can change in high-density lipoprotein cholesterol levels reduce cardiovascular risk?

2004 • 48 citations

High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients

2002 • 38 citations

A Prospective, Randomized Trial of Phenytoin in Nonepileptic Subjects With Reduced HDL Cholesterol

1995 • 26 citations

Favorable cardiac risk among elderly breast carcinoma survivors

2003 • 21 citations

Effect of gemfibrozil on apolipoprotein B secretion and diacylglycerol acyltransferase activity in human hepatoblastoma (HepG2) cells

2002 • 19 citations

Effects of Phenytoin on Plasma High‐Density Lipoprotein Cholesterol Levels in Men with Low Levels of High‐Density Lipoprotein Cholesterol

1995 • 19 citations

HYPERALPHALIPOPROTEINEMIA AND PROSTAGLANDIN I2 STABILITY

1997 • 18 citations

50th anniversary historical article. Acute coronary syndromes: the degree and morphology of coronary stenoses.

2000 • 14 citations

Peroxisome proliferator-activated receptor ligands in atherosclerosis

2004 • 9 citations

Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration

2004 • 9 citations

Comparative analysis of oestrogen and raloxifene effects on the phospholipid composition of high density lipoproteins in healthy postmenopausal women

2003 • 5 citations