Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors.

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

1996 • 727 citations

Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid

1999 • 517 citations

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions

1999 • 411 citations

Lysophosphatidic Acid Receptors

2000 • 404 citations

Differential Coupling of the Sphingosine 1-Phosphate Receptors Edg-1, Edg-3, and H218/Edg-5 to the Gi, Gq, and G12 Families of Heterotrimeric G Proteins

1999 • 329 citations

Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

1995 • 325 citations

Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8

2000 • 323 citations

A single receptor encoded by vzg-1 / lp _A1 / edg- 2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

1998 • 280 citations

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin

1992 • 266 citations

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species

2000 • 255 citations

EDG6, a Novel G-Protein-Coupled Receptor Related to Receptors for Bioactive Lysophospholipids, Is Specifically Expressed in Lymphoid Tissue

1998 • 231 citations

Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate

2000 • 206 citations

Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Control by Phosphoinositide‐Ca²⁺ Signaling and Rho

1996 • 198 citations

Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes

1996 • 173 citations

Recombinant Human G Protein-Coupled Lysophosphatidic Acid Receptors Mediate Intracellular Calcium Mobilization

1998 • 163 citations

Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate

2000 • 155 citations

Linguistic Ability in Early Life and the Neuropathology of Alzheimer's Disease and Cerebrovascular Disease: Findings from the Nun Study

2000 • 144 citations

Identification of Diacylglycerol Pyrophosphate as a Novel Metabolic Product of Phosphatidic Acid during G-protein Activation in Plants

1996 • 144 citations

Lysophosphatidic Acid-induced Mitogenesis Is Regulated by Lipid Phosphate Phosphatases and Is Edg-receptor Independent

2001 • 136 citations

Naturally Occurring Analogs of Lysophosphatidic Acid Elicit Different Cellular Responses through Selective Activation of Multiple Receptor Subtypes

1998 • 124 citations

Transduction of intracellular calcium signals through G protein-mediated activation of phospholipase C by recombinant sphingosine 1-phosphate receptors.

1999 • 123 citations

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis

1995 • 113 citations

Physiological responses to lysophosphatidic acid and related glycero-phospholipids

2001 • 93 citations

Biochemical Characterization of the Interaction of Lipid Phosphoric Acids with Human Platelets: Comparison with Platelet Activating Factor

1994 • 81 citations

Structure−Activity Analysis of the Effects of Lysophosphatidic Acid on Platelet Aggregation

1999 • 76 citations

Proinflammatory Macrophage-activating Properties of the Novel Phospholipid Diacylglycerol Pyrophosphate

1999 • 65 citations

N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors.

1996 • 57 citations

Characterization of a Receptor Subtype-Selective Lysophosphatidic Acid Mimetic

1998 • 52 citations

Diacylglycerol pyrophosphate, a novel phospholipid compound

1993 • 50 citations

Two Novel Xenopus Homologs of Mammalian LPA1/EDG-2 Function as Lysophosphatidic Acid Receptors inXenopus Oocytes and Mammalian Cells

2001 • 37 citations

Differential Inhibition of Lysophosphatidate Signaling by Volatile Anesthetics

1997 • 26 citations

Pharmacological Characterization of Phospholipid Growth‐Factor Receptors

2000 • 22 citations

Local anesthetics inhibit receptors coupled to phosphoinositide signaling in

1997 • 13 citations

A novel lysophosphatidic acid analog, LXR-1035, inhibits leukocyte-endothelium interaction via inhibition of cell adhesion molecules

2000 • 5 citations

Lysophospholipid growth factors

2000 • 2 citations