A Monoselective Sphingosine-1-Phosphate Receptor-1 Agonist Prevents Allograft Rejection in a Stringent Rat Heart Transplantation Model

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Improved technique of heart transplantation in rats

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2000 • 364 citations

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2004 • 329 citations

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2004 • 313 citations

First Human Trial of FTY720, a Novel Immunomodulator, in Stable Renal Transplant Patients

2002 • 272 citations

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2002 • 265 citations

S1P1-Selective In Vivo-Active Agonists from High- Throughput Screening: Off-the-Shelf Chemical Probes of Receptor Interactions, Signaling, and Fate

2005 • 235 citations

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2004 • 221 citations

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2001 • 175 citations

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2000 • 174 citations

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2005 • 162 citations

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

2003 • 124 citations

A Single Amino Acid Determines Lysophospholipid Specificity of the S1P1 (EDG1) and LPA1 (EDG2) Phospholipid Growth Factor Receptors

2001 • 110 citations

Transduction of Multiple Effects of Sphingosine 1-Phosphate (S1P) on T Cell Functions by the S1P1 G Protein-Coupled Receptor

2003 • 99 citations

Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (S1P₁) Receptor Agonists with Exceptional Selectivity against S1P₂ and S1P₃

2005 • 98 citations

FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression

2001 • 90 citations

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2002 • 83 citations

Physiological sphingosine 1‐phosphate requirement for optimal activity of mouse CD4⁺25⁺regulatory T Cells

2004 • 39 citations

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2006 • 36 citations

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2001 • 22 citations