Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

Sphingosine-1-phosphate: an enigmatic signalling lipid

2003 • 2,022 citations

Inducible Gene Targeting in Mice

1995 • 1,897 citations

CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS

2004 • 840 citations

Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients

2005 • 772 citations

Essential Role for Sphingosine Kinases in Neural and Vascular Development

2005 • 719 citations

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development

1995 • 712 citations

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

2005 • 681 citations

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

2006 • 443 citations

Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

2004 • 439 citations

Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration

2004 • 436 citations

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo

2006 • 400 citations

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

2005 • 278 citations

Signaling and biological actions of sphingosine 1-phosphate

2003 • 272 citations

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720

2005 • 263 citations

Interstitial fluid lipoproteins.

1987 • 223 citations

Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720

2005 • 211 citations

Sphingosine 1-Phosphate Induces Platelet Activation through an Extracellular Action and Shares a Platelet Surface Receptor with Lysophosphatidic Acid

1997 • 200 citations

Sphingosine 1-phosphate: synthesis and release

2001 • 187 citations

Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists

2006 • 156 citations

Sphingosine-1-phosphate receptors and the development of the vascular system

2002 • 145 citations

Metabolism and functional effects of sphingolipids in blood cells

1999 • 116 citations

Neonatally Induced Inactivation of the Vascular Cell Adhesion Molecule 1 Gene Impairs B Cell Localization and T Cell–Dependent Humoral Immune Response

2001 • 108 citations

Sphingosine 1-Phosphate–Related Metabolism in the Blood Vessel

2005 • 85 citations

Thymic microvascular system

1997 • 83 citations

A scanning electron-microscopic study of the rat thymus with special reference to cell types and migration of lymphocytes into the general circulation

1986 • 74 citations

The passage of thymic lymphocytes to the circulation in the rat

1967 • 19 citations