Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1995 • 1,407 citations

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 • 856 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

1996 • 830 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 • 739 citations

RNA POLYMERASE II

1991 • 729 citations

BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

1996 • 721 citations

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1998 • 718 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

Diversity and specialization of mammalian SWI/SNF complexes.

1996 • 703 citations

Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

1997 • 692 citations

RSC, an Essential, Abundant Chromatin-Remodeling Complex

1996 • 680 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

1979 • 678 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

1996 • 645 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase

1994 • 636 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

1989 • 576 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

GENES AFFECTING THE REGULATION OF SUC2 GENE EXPRESSION BY GLUCOSE REPRESSION IN SACCHAROMYCES CEREVISIAE

1984 • 567 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

1996 • 556 citations

Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters

1997 • 546 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

1980 • 541 citations

5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

1997 • 540 citations

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

1997 • 539 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5

1994 • 523 citations

Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II

1997 • 511 citations

Reversible Phosphorylation of the C-terminal Domain of RNA Polymerase II

1996 • 498 citations

The downstream core promoter element, DPE, is conserved fromDrosophila to humans and is recognized by TAF_II60 of Drosophila

1997 • 487 citations

Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines

1997 • 480 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

1997 • 467 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

1998 • 460 citations

Nucleosome loss activates yeast downstream promoters in vivo

1988 • 456 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

BRCA1 is a component of the RNA polymerase II holoenzyme

1997 • 450 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

p53 Transcriptional Activation Mediated by Coactivators TAF _II 40 and TAF _II 60

1995 • 438 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1995 • 431 citations

The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1

1992 • 427 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

A kinase–cyclin pair in the RNA polymerase II holoenzyme

1995 • 418 citations

Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure.

1995 • 416 citations

Transcription by RNA polymerase II: initiator‐directed formation of transcription‐competent complexes ¹

1992 • 412 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

1992 • 407 citations

Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.

1996 • 406 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1994 • 402 citations

Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response.

1991 • 400 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells

1992 • 392 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

Initiation of Transcription by RNA Polymerase II: A Multi-step Process

1993 • 390 citations

New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB

1998 • 384 citations

A mediator required for activation of RNA polymerase II transcription in vitro

1991 • 383 citations

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

1994 • 381 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

The SWI-SNF complex: a chromatin remodeling machine?

1995 • 379 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

DNA topology and a minimal set of basal factors for transcription by RNA polymerase II

1993 • 374 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

Association of Cdk-activating kinase subunits with transcription factor TFIIH

1995 • 366 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Function of a yeast TATA element-binding protein in a mammalian transcription system

1988 • 364 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Evidence That Spt6p Controls Chromatin Structure by a Direct Interaction with Histones

1996 • 352 citations

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

1996 • 351 citations

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)

1990 • 346 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae.

1985 • 342 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 334 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene Promoter

1988 • 320 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I

1987 • 317 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae.

1991 • 315 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Crystal structure of a yeast TFIIA/TBP/DNA complex

1996 • 312 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II

1989 • 304 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.

1992 • 302 citations

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

1998 • 299 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 299 citations

The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.

1993 • 299 citations

The RNA polymerase II holoenzyme and its implications for gene regulation

1995 • 297 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences.

1989 • 291 citations

Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II

1995 • 290 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

RNA polymerase II transcription initiation: A structural view

1997 • 282 citations

Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.

1990 • 281 citations

Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

1995 • 280 citations

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

1997 • 277 citations

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.

1994 • 276 citations

TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA

1994 • 275 citations

An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei.

1995 • 275 citations

Cloning of a human gene encoding the general transcription initiation factor IIB

1991 • 274 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

A Review of Phenotypes in Saccharomyces cerevisiae

1997 • 270 citations

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex.

1992 • 265 citations

The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiae.

1985 • 265 citations

Crystal Structure of the Yeast TFIIA/TBP/DNA Complex

1996 • 263 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

Structural similarity between TAFs and the heterotetrameric core of the histone octamer

1996 • 258 citations

Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions

1989 • 256 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

A yeast activity can substitute for the HeLa cell TATA box factor

1988 • 253 citations

A suppressor of a HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases

1989 • 251 citations

Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II.

1989 • 250 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.

1995 • 245 citations

Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S. cerevisiae

1984 • 243 citations

The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB

1992 • 241 citations

Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro.

1991 • 241 citations

The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes

1996 • 240 citations

SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo

1989 • 239 citations

Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.

1995 • 239 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH.

1996 • 238 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.

1988 • 236 citations

Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo

1998 • 235 citations

Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation

1993 • 234 citations

The price of repression

1995 • 232 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Identification and characterization of factor IIH.

1992 • 230 citations

Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.

1993 • 229 citations

Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates.

1992 • 228 citations

Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters

1992 • 228 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 227 citations

Chromatin remodeling and transcription

1997 • 227 citations

Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae.

1988 • 226 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast

1996 • 223 citations

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II

1997 • 223 citations

The Cdk-Activating Kinase (CAK) from Budding Yeast

1996 • 220 citations

Polymerase II Promoter Activation: Closed Complex Formation and ATP-Driven Start Site Opening

1992 • 220 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.

1992 • 217 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

A wide variety of DNA sequences can functionally replace a yeast TATA element for transcriptional activation.

1990 • 212 citations

Drosophila TAF _II 150: Similarity to Yeast Gene TSM-1 and Specific Binding to Core Promoter DNA

1994 • 212 citations

KIN28 Encodes a C-Terminal Domain Kinase That Controls mRNA Transcription in Saccharomyces cerevisiae but Lacks Cyclin-Dependent Kinase-Activating Kinase (CAK) Activity

1995 • 208 citations

Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function invivo

1997 • 208 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

1998 • 207 citations

TFIID binds in the minor groove of the TATA box

1991 • 206 citations

Activator-dependent regulation of transcriptional pausing on nucleosomal templates.

1996 • 205 citations

Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the "TATA box".

1984 • 204 citations

Role for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression

1997 • 203 citations

Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.

1991 • 202 citations

GENETICS OF TRANSCRIPTIONAL REGULATION IN YEAST: Connections to the RNA Polymerase II CTD

1997 • 202 citations

Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization.

1996 • 200 citations

The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo

1992 • 200 citations

NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

1994 • 199 citations

CTD kinase associated with yeast RNA polymerase II initiation factor b

1991 • 199 citations

Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4

1992 • 196 citations

Cloning of an Inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1

1997 • 195 citations

DNA-binding properties of the yeast SWI/SNF complex

1996 • 195 citations

Transcription : mechanisms and regulation

1994 • 195 citations

Structure and functional properties of human general transcription factor IIE

1991 • 194 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

TAFII250 Is a Bipartite Protein Kinase That Phosphorylates the Basal Transcription Factor RAP74

1996 • 194 citations

Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II

1989 • 193 citations

Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae.

1987 • 192 citations

Dynamic interaction between a Drosophila transcription factor and RNA polymerase II.

1989 • 191 citations

Yeast TATA-box transcription factor gene.

1989 • 191 citations

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

1995 • 189 citations

Distinct TFIID complexes mediate the effect of different transcriptional activators.

1993 • 189 citations

HDA1 and HDA3 Are Components of a Yeast Histone Deacetylase (HDA) Complex

1996 • 189 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

TheKIN28Gene is Required both for RNA Polymerase II Mediated Transcription and Phosphorylation of the Rpb1p CTD

1995 • 185 citations

Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein

1995 • 184 citations

A histone octamer-like structure within TFIID

1996 • 182 citations

A yeast TFIIB-related factor involved in RNA polymerase III transcription.

1992 • 181 citations

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

1991 • 179 citations

Yeast TAFII145 Functions as a Core Promoter Selectivity Factor, Not a General Coactivator

1997 • 179 citations

Kinetic analysis of yeast TFIID-TATA box complex formation suggests a multi-step pathway.

1992 • 178 citations

Activator-induced conformational change in general transcription factor TFIIB

1994 • 177 citations

SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae.

1992 • 176 citations

ADA3, a Putative Transcriptional Adaptor, Consists of Two Separable Domains and Interacts with ADA2 and GCN5 in a Trimeric Complex

1995 • 175 citations

A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK

1996 • 174 citations

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein.

1994 • 174 citations

Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast.

1995 • 174 citations

YEAST TRANSCRIPTIONAL REGULATORY MECHANISMS

1995 • 173 citations

The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter

1992 • 172 citations

Civ1 (CAK In Vivo), a Novel Cdk-Activating Kinase

1996 • 172 citations

Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae.

1991 • 171 citations

The initiator directs the assembly of a transcription factor IID-dependent transcription complex.

1991 • 170 citations

A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID

1992 • 170 citations

Transcription Properties of a Cell Type–Specific TATA-Binding Protein, TRF

1997 • 170 citations

Interaction of TFIID in the minor groove of the TATA element

1991 • 170 citations

Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation

1994 • 170 citations

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

1991 • 170 citations

Human TAFII105 Is a Cell Type–Specific TFIID Subunit Related to hTAFII130

1996 • 169 citations

A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.

1992 • 168 citations

RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes.

1991 • 168 citations

IDENTIFICATION OF NEW GENES INVOLVED IN THE REGULATION OF YEAST ALCOHOL DEHYDROGENASE II

1984 • 167 citations

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

1993 • 167 citations

An alternative pathway for transcription initiation involving TFII-I

1993 • 166 citations

Pre-mRNA Processing and the CTD of RNA Polymerase II: The Tail That Wags the Dog?

1997 • 165 citations

Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome

1996 • 165 citations

A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIB fraction

1992 • 163 citations

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF _II 250

1994 • 163 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

1994 • 163 citations

Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae.

1992 • 162 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA.

1992 • 160 citations

TFG3/TAF30/ANC1, a Component of the Yeast SWI/SNF Complex That Is Similar to the Leukemogenic Proteins ENL and AF-9

1996 • 158 citations

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

1996 • 158 citations

PCF4 encodes an RNA polymerase III transcription factor with homology to TFIIB

1992 • 157 citations

The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs.

1990 • 156 citations

An ATP-dependent inhibitor of TBP binding to DNA.

1993 • 156 citations

The TATA-binding protein and associated factors are components of pol III transcription factor TFIIIB

1992 • 156 citations

A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIB

1992 • 155 citations

RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection

1994 • 155 citations

A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein

1995 • 155 citations

Yeast and human TFIID with altered DNA-binding specificity for TATA elements

1992 • 155 citations

DNA Melting on Yeast RNA Polymerase II Promoters

1993 • 154 citations

Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor.

1989 • 154 citations

Cdc73p and Paf1p Are Found in a Novel RNA Polymerase II-Containing Complex Distinct from the Srbp-Containing Holoenzyme

1997 • 153 citations

Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

1997 • 153 citations

Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II.

1991 • 152 citations

A Class of Activation Domains Interacts Directly with TFIIA and Stimulates TFIIA-TFIID-Promoter Complex Assembly

1995 • 152 citations

Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

1994 • 151 citations

SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3

1992 • 151 citations

GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators

1990 • 149 citations

Mutations Causing Constitutive Invertase Synthesis in Yeast: Genetic Interactions with snf Mutations

1987 • 149 citations

TFIIF-TAF-RNA polymerase II connection.

1994 • 148 citations

Identification of a minimal set of proteins that is sufficient for accurate initiation of transcription by RNA polymerase II.

1993 • 148 citations

Paf1p, an RNA Polymerase II-Associated Factor inSaccharomyces cerevisiae, May Have both Positive and Negative Roles in Transcription

1996 • 148 citations

Mutations in the RNA Polymerase II Transcription Machinery Suppress the Hyperrecombination Mutant hpr1 Δ of Saccharomyces cerevisiae

1996 • 147 citations

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.

1988 • 145 citations

Mutations that suppress the deletion of an upstream activating sequence in yeast: involvement of a protein kinase and histone H3 in repressing transcription in vivo.

1993 • 144 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Genetics of eukaryotic RNA polymerases I, II, and III

1993 • 143 citations

The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA.

1995 • 143 citations

Yeast TAFII145 Required for Transcription of G1/S Cyclin Genes and Regulated by the Cellular Growth State

1997 • 143 citations

The mammalian TFIID protein is present in two functionally distinct complexes.

1991 • 142 citations

Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast.

1989 • 141 citations

Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.

1987 • 141 citations

Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase

1987 • 141 citations

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.

1996 • 141 citations

A Large Protein Complex Containing the Yeast Sin3p and Rpd3p Transcriptional Regulators

1997 • 140 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

A Functional Interaction between the Carboxy-Terminal Domain of RNA Polymerase II and Pre-mRNA Splicing

1997 • 139 citations

DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II

1994 • 138 citations

Genetic properties and chromatin structure of the yeast gal regulatory element: an enhancer-like sequence.

1984 • 137 citations

Isolation of Two Genes That Encode Subunits of the Yeast Transcription Factor IIA

1992 • 137 citations

GENES AFFECTING THE EXPRESSION OF CYTOCHROME c IN YEAST: GENETIC MAPPING AND GENETIC INTERACTIONS

1980 • 137 citations

Purification and characterization of a phosphatase from HeLa cells which dephosphorylates the C-terminal domain of RNA polymerase II

1994 • 137 citations

Genetic Interaction between Transcription Elongation Factor TFIIS and RNA Polymerase II

1992 • 136 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification and Analysis of Transcription Factor ILA and Identification of Transcription Factor IIJ

1992 • 136 citations

Characterization of sua7 mutations defines a domain of TFIIB involved in transcription start site selection in yeast.

1994 • 136 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 136 citations

Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ

1995 • 134 citations

Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity.

1995 • 133 citations

RNA Polymerase II Holoenzyme Recruitment Is Sufficient to Remodel Chromatin at the Yeast PHO5 Promoter

1997 • 133 citations

MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH.

1996 • 133 citations

Repression of Gene Expression by an Exogenous Sequence Element Acting in Concert with a Heterogeneous Nuclear Ribonucleoprotein-Like Protein, Nrd1, and the Putative Helicase Sen1

1996 • 133 citations

The SPT6 gene is essential for growth and is required for delta-mediated transcription in Saccharomyces cerevisiae.

1987 • 132 citations

The TBP-TFIIA Interaction in the Response to Acidic Activators in Vivo

1995 • 132 citations

Dominant negative mutations in yeast TFIID define a bipartite DNA-binding region

1991 • 132 citations

Functional domains of transcription factor TFIIB.

1993 • 131 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and subunit composition of transcription factor IIF.

1990 • 129 citations

Requirement of a corepressor for Dr1-mediated repression of transcription.

1996 • 128 citations

Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae.

1992 • 127 citations

An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.

1989 • 127 citations

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes

1997 • 127 citations

Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

1995 • 126 citations

Mechanism of TATA-binding protein recruitment to a TATA-less class III promoter

1992 • 125 citations

A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver.

1992 • 124 citations

Yeast TATA binding protein interaction with DNA: fluorescence determination of oligomeric state, equilibrium binding, on-rate, and dissociation kinetics

1995 • 123 citations

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae.

1995 • 123 citations

RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.

1992 • 122 citations

A Portion of RNA Polymerase II Molecules Has a Component Essential for Stress Responses and Stress Survival

1993 • 122 citations

Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae

1992 • 121 citations

The Activity of COOH-terminal Domain Phosphatase Is Regulated by a Docking Site on RNA Polymerase II and by the General Transcription Factors IIF and IIB

1995 • 121 citations

Sfh1p, a Component of a Novel Chromatin-Remodeling Complex, Is Required for Cell Cycle Progression

1997 • 120 citations

Solution structure of the c-terminal core domain of human TFIIB: Similarity to cyclin A and interaction with TATA-binding protein

1995 • 120 citations

Structural and Functional Analysis of Yeast Putative Adaptors

1996 • 119 citations

Transcriptional repression directed by the yeast α2 protein in vitro

1994 • 118 citations

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.

1993 • 118 citations

A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts.

1989 • 117 citations

Positive patches and negative noodles: linking RNA processing to transcription?

1993 • 117 citations

SSNGenes That Affect Transcriptional Repression inSaccharomyces cerevisiaeEncode SIN4, ROX3, and SRB Proteins Associated with RNA Polymerase II

1996 • 117 citations

Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.

1989 • 116 citations

Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.

1996 • 116 citations

Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS

1993 • 116 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

RAP30/74: a general initiation factor that binds to RNA polymerase II.

1988 • 115 citations

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

1995 • 114 citations

Increased Recruitment of TATA-Binding Protein to the Promoter by Transcriptional Activation Domains in Vivo

1994 • 114 citations

SPT20/ADA5 Encodes a Novel Protein Functionally Related to the TATA-Binding Protein and Important for Transcription in Saccharomyces cerevisiae

1996 • 114 citations

Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).

1994 • 114 citations

p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.

1994 • 114 citations

Identification of Native Complexes Containing the Yeast Coactivator/Repressor Proteins NGG1/ADA3 and ADA2

1997 • 113 citations

Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation

1996 • 113 citations

Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA.

1994 • 112 citations

Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein.

1993 • 111 citations

Transcription Elongation through DNA Arrest Sites

1997 • 111 citations

The yeast general transcription factor TFIIA is composed of two polypeptide subunits.

1991 • 110 citations

Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site.

1994 • 110 citations

Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

1993 • 110 citations

A Novel Collection of Accessory Factors Associated with Yeast RNA Polymerase II

1996 • 110 citations

Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity.

1989 • 110 citations

Trajectory of DNA in the RNA polymerase II transcription preinitiation complex

1997 • 109 citations

CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters.

1993 • 109 citations

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.

1994 • 109 citations

The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection.

1987 • 108 citations

The NOT, SPT3, and MOT1 Genes Functionally Interact To Regulate Transcription at Core Promoters

1996 • 108 citations

TAFs and TFIIA mediate differential utilization of the tandem Adh promoters

1995 • 108 citations

A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA.

1993 • 108 citations

Recruiting TATA-Binding Protein to a Promoter: Transcriptional Activation without an Upstream Activator

1995 • 108 citations

Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p)

1997 • 107 citations

High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex.

1996 • 107 citations

RPD3 Encodes a Second Factor Required To Achieve Maximum Positive and Negative Transcriptional States in Saccharomyces cerevisiae

1991 • 106 citations

Synergistic release from glucose repression by mig1 and ssn mutations in Saccharomyces cerevisiae.

1994 • 105 citations

Role for the Amino-Terminal Region of Human TBP in U6 snRNA Transcription

1997 • 105 citations

The human general co-factors

1996 • 105 citations

ADA1, a Novel Component of the ADA/GCN5 Complex, Has Broader Effects than GCN5, ADA2, or ADA3

1997 • 104 citations

Yeast and Human TATA-Binding Proteins Have Nearly Identical DNA Sequence Requirements for Transcription In Vitro

1990 • 104 citations

Evidence that Spt3 Functionally Interacts with Mot1, TFIIA, and TATA-Binding Protein To Confer Promoter-Specific Transcriptional Control in Saccharomyces cerevisiae

1997 • 104 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

Mediator of transcriptional regulation

1996 • 103 citations

A Complex Composed of Tup1 and Ssn6 Represses Transcription in Vitro

1997 • 103 citations

2.1 Å resolution refined structure of a TATA box-binding protein (TBP)

1994 • 102 citations

The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription.

1989 • 101 citations

Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE

1991 • 100 citations

Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II.

1994 • 100 citations

The Role of Multisite Phosphorylation in the Regulation of RNA Polymerase II Activity

1994 • 100 citations

RNA polymerase II subunit RPB9 is required for accurate start site selection.

1995 • 100 citations

Related RNA Polymerase-binding Regions in Human RAP30/74 And Escherichia coli σ70

1991 • 99 citations

Factors involved in specific transcription by mammalian RNA polymerase II. RNA polymerase II-associating protein 30 is an essential component of transcription factor IIF.

1988 • 98 citations

RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation.

1993 • 98 citations

Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation.

1995 • 97 citations

A multisubunit transcription factor essential for accurate initiation by RNA polymerase II

1989 • 97 citations

Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo.

1996 • 97 citations

Mutations in the Second Largest Subunit of RNA Polymerase II Cause 6-Azauracil Sensitivity in Yeast and Increased Transcriptional Arrest in Vitro

1996 • 97 citations

Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.

1996 • 97 citations

Model for binding of transcription factor TFIIB to the TBP-DNA complex

1995 • 97 citations

Molecular Analysis of the SNF2/SWI2 Protein Family Member MOT1, an ATP-Driven Enzyme That Dissociates TATA-Binding Protein from DNA

1997 • 96 citations

ADA5/SPT20 Links the ADA and SPT Genes, Which Are Involved in Yeast Transcription

1996 • 96 citations

Nucleotide Excision Repair in Yeast Is Mediated by Sequential Assembly of Repair Factors and Not by a Pre-assembled Repairosome

1996 • 96 citations

Transcription Factor IID Mutants Defective for Interaction with Transcription Factor IIA

1992 • 95 citations

Analysis of the Yeast Transcription Factor TFIIA: Distinct Functional Regions and a Polymerase II-Specific Role in Basal and Activated Transcription

1995 • 95 citations

Considerations of transcriptional control mechanisms: Do TFIID–core promoter complexes recapitulate nucleosome-like functions?

1997 • 94 citations

Sequence of general transcription factor TFIIB and relationships to other initiation factors.

1991 • 94 citations

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription.

1994 • 93 citations

The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo

1997 • 93 citations

Yeast homologues of higher eukaryotic TFIID subunits

1996 • 93 citations

Analysis of the Role of TFIIE in Basal Transcription and TFIIH-Mediated Carboxy-Terminal Domain Phosphorylation through Structure-Function Studies of TFIIE-α

1995 • 92 citations

Multiple sets of basal factors initiate transcription by RNA polymerase II

1994 • 92 citations

SSN20 is an essential gene with mutant alleles that suppress defects in SUC2 transcription in Saccharomyces cerevisiae.

1987 • 91 citations

The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose.

1994 • 91 citations

A Specialized Nucleosome Modulates Transcription Factor Access to a C. glabrata Metal Responsive Promoter

1996 • 90 citations

The TATA box binding protein

1996 • 90 citations

Delineation of two functional regions of transcription factor TFIIB.

1993 • 90 citations

Transcriptional Activation in an Improved Whole-Cell Extract from Saccharomyces cerevisiae

1991 • 90 citations

The Yeast TFB1 and SSL1 Genes, Which Encode Subunits of Transcription Factor IIH, Are Required for Nucleotide Excision Repair and RNA Polymerase II Transcription

1995 • 90 citations

Conserved sequence motifs in the small subunit of human general transcription factor TFIIE

1991 • 89 citations

Immunopurification of yeast TATA-binding protein and associated factors. Presence of transcription factor IIIB transcriptional activity

1993 • 88 citations

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.

1994 • 88 citations

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

1993 • 88 citations

Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor.

1990 • 88 citations

SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.

1994 • 88 citations

TAF_II250-dependent transcription of cyclin A is directed by ATF activator proteins

1997 • 88 citations

Yeast Taf170 is encoded by MOT1 and exists in a TATA box-binding protein (TBP)-TBP-associated factor complex distinct from transcription factor IID.

1994 • 87 citations

TBP mutants defective in activated transcription in vivo.

1995 • 87 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Role of Transcription Factors IIA, IID, and IIB during Formation of a Transcription-Competent Complex

1990 • 87 citations

Dimerization of the TATA Binding Protein

1995 • 86 citations

Saccharomyces cerevisiae BUR6Encodes a DRAP1/NC2α Homolog That Has both Positive and Negative Roles in Transcription In Vivo

1997 • 86 citations

RNA polymerase transcription factor IIH holoenzyme from yeast.

1994 • 85 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE.

1990 • 84 citations

A Yeast Transcriptional Stimulatory Protein Similar to Human PC4

1996 • 84 citations

The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations.

1994 • 83 citations

Functional dissection of TFIIB domains required for TFIIB–TFIID–promoter complex formation and basal transcription activity

1993 • 82 citations

Isolation of Saccharomyces cerevisiae mutants constitutive for invertase synthesis

1986 • 80 citations

Genes For Tfb2, Tfb3, and Tfb4 Subunits of Yeast Transcription/Repair Factor IIH

1997 • 79 citations

A Role for ATP and TFIIH in Activation of the RNA Polymerase II Preinitiation Complex Prior to Transcription Initiation

1996 • 79 citations

Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA.

1989 • 79 citations

Composition of transcription factor B-TFIID.

1992 • 79 citations

Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure

1997 • 78 citations

SPT6, an essential gene that affects transcription in Saccharomyces cerevisiae, encodes a nuclear protein with an extremely acidic amino terminus.

1990 • 77 citations

Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase

1992 • 77 citations

Mechanism of Differential Utilization of the his3 T_R and T_C TATA Elements

1995 • 77 citations

TAFs: Guilt by Association?

1997 • 77 citations

The Kin28 Protein Kinase is Associated with a Cyclin in Saccharomyces cerevisiae

1993 • 77 citations

TSF3, a global regulatory protein that silences transcription of yeast GAL genes, also mediates repression by alpha 2 repressor and is identical to SIN4.

1993 • 77 citations

PLEIOTROPIC MUTATIONS AT THE TUP1 LOCUS THAT AFFECT THE EXPRESSION OF MATING-TYPE-DEPENDENT FUNCTIONS IN SACCHAROMYCES CEREVISIAE

1980 • 76 citations

Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH).

1994 • 75 citations

SSL1, a suppressor of a HIS4 5'-UTR stem-loop mutation, is essential for translation initiation and affects UV resistance in yeast.

1992 • 75 citations

CIF, an essential cofactor for TFIID-dependent initiator function.

1996 • 74 citations

The human general co-factors

1996 • 74 citations

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

1995 • 73 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of general transcription factor IIE

1991 • 73 citations

A Novel 66-Kilodalton Protein Complexes with Rrn6, Rrn7, and TATA-Binding Protein To Promote Polymerase I Transcription Initiation in Saccharomyces cerevisiae

1996 • 73 citations

Evidence That the Transcriptional Regulators SIN3 and RPD3, and a Novel Gene (SDS3) with Similar Functions, Are Involved in Transcriptional Silencing in S. cerevisiae

1996 • 73 citations

Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex. A common pathway for formation of preinitiation intermediates at many TATA and TATA-less promoters

1994 • 73 citations

Six Human RNA Polymerase Subunits Functionally Substitute for Their Yeast Counterparts

1995 • 72 citations

Two Types of TATA Elements for the CYC1 Gene of the Yeast Saccharomyces cerevisiae

1991 • 71 citations

Identification of RTF1, a Novel Gene Important for TATA Site Selection by TATA Box-Binding Protein in Saccharomyces cerevisiae

1997 • 71 citations

Potential RNA polymerase II-induced interactions of transcription factor TFIIB.

1993 • 70 citations

Regulation of HIS4 expression by the Saccharomyces cerevisiae SIN4 transcriptional regulator.

1995 • 70 citations

The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae.

1991 • 70 citations

Phosphorylation negatively regulates the function of coactivator PC4.

1994 • 70 citations

A Transcriptional Mediator Protein That Is Required for Activation of Many RNA Polymerase II Promoters and Is Conserved from Yeast to Humans

1997 • 69 citations

Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107

1994 • 68 citations

Dimerization of TFIID When Not Bound to DNA

1996 • 68 citations

Multifunctional RNA polymerase II initiation factor delta from rat liver. Relationship between carboxyl-terminal domain kinase, ATPase, and DNA helicase activities

1993 • 68 citations

The DNA-dependent ATPase activity associated with the class II basic transcription factor BTF2/TFIIH

1994 • 67 citations

Mediator of transcriptional regulation

1996 • 67 citations

A Minimal Set of RNA Polymerase II Transcription Protein Interactions

1996 • 66 citations

A novel mutation that affects utilization of galactose in Saccharomyces cerevisiae

1980 • 66 citations

New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae.

1991 • 66 citations

Accurate initiation by RNA polymerase II in a whole cell extract from Saccharomyces cerevisiae.

1990 • 65 citations

Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

1991 • 65 citations

47 Analysis of SPT Genes: A Genetic Approach toward Analysis of TFIID, Histones, and Other Transcription Factors of Yeast

1992 • 65 citations

Identification of Rox3 as a Component of Mediator and RNA Polymerase II Holoenzyme

1997 • 64 citations

Isolation and Characterization of TAF25, an Essential Yeast Gene That Encodes an RNA Polymerase II-specific TATA-binding Protein-associated Factor

1996 • 64 citations

A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators

1997 • 64 citations

RETRACTED: TAFIIs Mediate Activation of Transcription in the Drosophila Embryo

1996 • 64 citations

The TATA-binding protein participates in TFIIIB assembly on tRNA genes

1992 • 63 citations

Topological localization of the human transcription factors IIA, IIB, TATA box-binding protein, and RNA polymerase II-associated protein 30 on a class II promoter.

1994 • 63 citations

Role of the Mammalian Transcription Factors IIF, IIS, and IIX during Elongation by RNA Polymerase II

1991 • 63 citations

Purification and characterization of yeast RNA polymerase II transcription factor b.

1991 • 63 citations

Localization of Subunits of Transcription Factors IIE and IIF Immediately Upstream of the Transcriptional Initiation Site of the Adenovirus Major Late Promoter

1996 • 62 citations

Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo

1997 • 62 citations

Gcn5p is involved in the acetylation of histone H3 in nucleosomes

1997 • 62 citations

A heteroduplex template circumvents the energetic requirement for ATP during activated transcription by RNA polymerase II

1994 • 61 citations

RPD1 (SIN3/UME4) Is Required for Maximal Activation and Repression of Diverse Yeast Genes

1991 • 61 citations

Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae.

1995 • 61 citations

TAFIIs Mediate Activation of Transcription in theDrosophilaEmbryo

1998 • 61 citations

Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae

1993 • 61 citations

Mutations in SPT16/CDC68 Suppress cis- and trans-Acting Mutations That Affect Promoter Function in Saccharomyces cerevisiae

1991 • 59 citations

Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding

1997 • 58 citations

Mutations on the DNA-Binding Surface of TATA-Binding Protein Can Specifically Impair the Response to Acidic Activators In Vivo

1995 • 58 citations

Genetic Analysis of the Large Subunit of Yeast Transcription Factor IIE Reveals Two Regions with Distinct Functions

1997 • 58 citations

Purification and characterization of yeast RNA polymerase II general initiation factor g

1992 • 57 citations

RAP74 induces promoter contacts by RNA polymerase II upstream and downstream of a DNA bend centered on the TATA box

1997 • 57 citations

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae

1996 • 56 citations

A New Class of Activation-Defective TATA-Binding Protein Mutants: Evidence for Two Steps of Transcriptional Activation In Vivo

1996 • 54 citations

Characterization of the Basal Inhibitor of Class II Transcription NC2 from Saccharomyces cerevisiae

1996 • 54 citations

The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function.

1992 • 54 citations

RNA Polymerase II-associated Protein (RAP) 74 Binds Transcription Factor (TF) IIB and Blocks TFIIB-RAP30 Binding

1996 • 53 citations

Dynamic Interaction between a Drosophila Transcription Factor and RNA Polymerase II

1989 • 53 citations

Molecular Analysis of SSN6, a Gene Functionally Related to the SNF1 Protein Kinase of Saccharomyces cerevisiae

1987 • 53 citations

Transcription Factor TFIIB Sites Important for Interaction with Promoter-Bound TFIID

1993 • 52 citations

The GAM1/SNF2 gene of Saccharomyces cerevisiae encodes a highly charged nuclear protein required for transcription of the STA1 gene

1991 • 51 citations

Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins.

1994 • 51 citations

The Yeast HRS1 Gene Is Involved in Positive and Negative Regulation of Transcription and Shows Genetic Characteristics Similar to SIN4 and GAL11

1997 • 51 citations

Characterization of mutations that suppress the temperature-sensitive growth of the hpr1 delta mutant of Saccharomyces cerevisiae.

1994 • 51 citations

A Presumptive Helicase (MOT1 Gene Product) Affects Gene Expression and Is Required for Viability in the Yeast Saccharomyces cerevisiae

1992 • 50 citations

Mutational Analysis of the D1/E1 Core Helices and the Conserved N-Terminal Region of Yeast Transcription Factor IIB (TFIIB): Identification of an N-terminal Mutant That Stabilizes TATA-Binding Protein-TFIIB-DNA Complexes

1997 • 50 citations

Amino Termini of Histones H3 and H4 Are Required for a1-α2 Repression in Yeast

1997 • 50 citations

The centromere and promoter factor 1, CPFI, of Saccharomyces cerevisiae modulates gene activity through a family of factors including SPT21, RPD1 (SIN3), RPD3 and CCR4

1993 • 50 citations

Cofractionation of the TATA-binding protein with the RNA polymerase III transcription factor TFIIIB

1992 • 49 citations

Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection.

1991 • 48 citations

Cloning of the cDNA for the TATA-binding protein-associated factor _II 170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila

1997 • 47 citations

Screens for extragenic mutations that fail to complement act1 alleles identify genes that are important for actin function in Saccharomyces cerevisiae.

1993 • 47 citations

DNA sequence elements required for transcription initiation of the Schizosaccharomyces pombe ADH gene in Saccharomyces cerevisiae

1990 • 46 citations

The SPT6 Gene is Essential for Growth and is Required for δ-Mediated Transcription in Saccharomyces cerevisiae

1987 • 46 citations

RAP30/74: A General Initiation Factor That Binds to RNA Polymerase II

1988 • 44 citations

Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA.

1996 • 44 citations

GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae

1988 • 43 citations

Role of a small RNA pol II subunit in TATA to transcription start site spacing

1994 • 43 citations

The SPT10 and SPT21 genes of Saccharomyces cerevisiae.

1994 • 43 citations

Purification and properties of Saccharomyces cerevisiae RNA polymerase II general initiation factor a

1992 • 42 citations

RNA polymerase-associated transcription factors

1991 • 42 citations

Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.

1994 • 42 citations

Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro.

1993 • 41 citations

Transcriptional Repression in Saccharomyces cerevisiae by a SIN3-LexA Fusion Protein

1993 • 41 citations

Transcriptional Corepression In Vitro: a Mot1p-Associated Form of TATA-Binding Protein Is Required for Repression by Leu3p

1996 • 41 citations

Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure.

1995 • 39 citations

Selective Use of TBP and TFIIB Revealed by a TATA-TBP-TFIIB Array with Altered Specificity

1997 • 39 citations

Involvement of the SIN4 Global Transcriptional Regulator in the Chromatin Structure of Saccharomyces cerevisiae

1992 • 39 citations

The Saccharomyces cerevisiae SIN3 Gene, a Negative Regulator of HO, Contains Four Paired Amphipathic Helix Motifs

1990 • 39 citations

ADA3: A Gene, Identified by Resistance to GAL4-VP16, with Properties Similar to and Different from those of ADA2

1993 • 38 citations

Identification and Analysis of a Functional Human Homolog of the SPT4 Gene of Saccharomyces cerevisiae

1996 • 38 citations

Subunits of Yeast RNA Polymerase II Transcription Factor TFIIH Encoded by the CCL1 Gene

1996 • 37 citations

The Yeast UME5 Gene Regulates the Stability of Meiotic mRNAs in Response to Glucose

1994 • 36 citations

A Severely Defective TATA-Binding Protein–TFIIB Interaction Does Not Preclude Transcriptional Activation In Vivo

1997 • 36 citations

Biochemical and genetic characterization of a yeast TFIID mutant that alters transcription in vivo and DNA binding in vitro.

1992 • 35 citations

Protein complexes for remodeling chromatin

1997 • 34 citations

Domain structure of a human general transcription initiation factor, TFIIF

1993 • 34 citations

Differential intrachromosomal hyper-recombination phenotype of spt4 and spt6 mutants of S. cerevisiae

1996 • 34 citations

The Histone Folds in Transcription Factor TFIID

1996 • 34 citations

Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae

1991 • 34 citations

The Saccharomyces cerevisiae SPT13/GAL11 Gene Has Both Positive and Negative Regulatory Roles in Transcription

1989 • 34 citations

Sequences required for transcriptional initiation of the Saccharomyces cerevisiae CYC7 genes.

1987 • 34 citations

A SAGA of histone acetylation and gene expression

1997 • 33 citations

CCR4 Is a Glucose-Regulated Transcription Factor Whose Leucine-Rich Repeat Binds Several Proteins Important for Placing CCR4 in Its Proper Promoter Context

1994 • 33 citations

The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function.

1996 • 32 citations

SPT10 and SPT21 Are Required for Transcription of Particular Histone Genes in Saccharomyces cerevisiae

1994 • 32 citations

Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae

1993 • 31 citations

Mutations in the Three Largest Subunits of Yeast RNA Polymerase II That Affect Enzyme Assembly

1991 • 31 citations

The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes.

1994 • 31 citations

Cloning and Characterization of an Essential Saccharomyces cerevisiae Gene, TAF40, Which Encodes yTAFII40, an RNA Polymerase II-specific TATA-binding Protein-associated Factor

1997 • 30 citations

TSF3, a Global Regulatory Protein That Silences Transcription of Yeast GAL Genes, Also Mediates Repression by α2 Repressor and Is Identical to SIN4

1993 • 30 citations

The Yeast HRS1 Gene Encodes a Polyglutamine-Rich Nuclear Protein Required for Spontaneous and hpr1-Induced Deletions Between Direct Repeats

1996 • 30 citations

MOT2 encodes a negative regulator of gene expression that affects basal expression of pheromone-responsive genes in Saccharomyces cerevisiae.

1994 • 29 citations

TSF1 to TSF6, required for silencing the Saccharomyces cerevisiae GAL genes, are global regulatory genes.

1993 • 29 citations

Mutations in the Yeast SRB2 General Transcription Factor Suppress hpr1-Induced Recombination and Show Defects in DNA Repair

1996 • 29 citations

Defective transcriptional activation by diverse VP16 mutants associated with a common inability to form open promoter complexes.

1994 • 28 citations

Equivalent mutations in the two repeats of yeast TATA-binding protein confer distinct TATA recognition specificities.

1994 • 28 citations

Identification and Analysis of the Human and Murine Putative Chromatin Structure Regulator SUPT6H andSupt6h

1996 • 28 citations

The Saccharomyces cerevisiae SPT14 gene is essential for normal expression of the yeast transposon, Ty, as well as for expression of the HIS4 gene and several genes in the mating pathway

1991 • 28 citations

A new nuclear suppressor system for a mitochondrial RNA polymerase mutant identifies an unusual zinc‐finger protein and a polyglutamine domain protein in Saccharomyces cerevisiae

1994 • 27 citations

[15] Yeast RNA polymerase II holoenzyme

1996 • 27 citations

Multiple TATA-Binding Factors Come Back Into Style

1997 • 27 citations

Mutations in the SPT4, SPT5, and SPT6 Genes Alter Transcription of a Subset of Histone Genes in Saccharomyces cerevisiae

1996 • 27 citations

The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations

1994 • 26 citations

A heteromeric transcription factor required for mammalian RNA polymerase II

1990 • 26 citations

Transcriptional Activation by TFIIB Mutants That Are Severely Impaired in Interaction with Promoter DNA and Acidic Activation Domains

1997 • 26 citations

The yeast CCR4 protein is neither regulated by nor associated with the SPT6 and SPT10 proteins and forms a functionally distinct complex from that of the SNF/SWI transcription factors.

1994 • 26 citations

SSN20 is an essential Gene with Mutant Alleles that Suppress Defects in SUC2 Transcription in Saccharomyces cerevisiae

1987 • 26 citations

Transcriptional activity of transcription factor IIE is dependent on zinc binding.

1994 • 25 citations

Potential RNA Polymerase II-Induced Interactions of Transcription Factor TFIIB

1993 • 25 citations

Control of DNA synthesis genes in budding yeast: involvement of the transcriptional modulatorMOT1 in the expression of the DNA polymerase α gene

1992 • 24 citations

SPT6, an Essential Gene That Affects Transcription in Saccharomyces cerevisiae, Encodes a Nuclear Protein with an Extremely Acidic Amino Terminus

1990 • 22 citations

SHI, a new yeast gene affecting the spacing between TATA and transcription initiation sites.

1991 • 22 citations

Two Alternative Pathways of Transcription Initiation in the Yeast Negative Regulatory Gene GAL80

1994 • 22 citations

Human Supt5h protein, a putative modulator of chromatin structure, is reversibly phosphorylated in mitosis

1997 • 22 citations

Mutations in a Conserved Region of RNA Polymerase II Influence the Accuracy of mRNA Start Site Selection

1991 • 22 citations

Promoter Structure-dependent Functioning of the General Transcription Factor IIE in Saccharomyces cerevisiae

1997 • 22 citations

Transcription: Why are TAFs essential?

1997 • 21 citations

Comparison of the sequences of the nagE operons from Klebsiella pneumoniae and Escherichia colt K12: Enhanced variability of the enzyme IIN-acetylglucosamine in regions connecting functional domains

1991 • 21 citations

Identifying a Species-Specific Region of Yeast TFIIB In Vivo

1996 • 21 citations

Mutations in GCR3, a Gene Involved in the Expression of Glycolytic Genes in Saccharomyces cerevisiae, Suppress the Temperature-Sensitive Growth of hpr1 Mutants

1996 • 21 citations

Homeodomain Interaction with the β Subunit of the General Transcription Factor TFIIE

1996 • 20 citations

Isolation and Characterization of the Human and Mouse Homologues (SUPT4H andSupt4h) of the Yeast SPT4 Gene

1996 • 20 citations

The TSM1 gene of Saccharomyces cerevisiae overlaps the MAT locus

1991 • 20 citations

A Yeast TATA-Binding Protein Mutant That Selectively Enhances Gene Expression from Weak RNA Polymerase II Promoters

1997 • 19 citations

Isolation, Sequencing, and Mapping of the Human Homologue of the Yeast Transcription Factor, SPT5

1996 • 18 citations

A Negative Cofactor Containing Dr1/p19 Modulates Transcription with TFIIA in a Promoter-specific Fashion

1996 • 18 citations

Exploring RNA polymerase II structure and function

1994 • 16 citations

Identification of cis-Acting Elements That Can Obviate a Requirement for the C-terminal Domain of RNA Polymerase II

1995 • 16 citations

Core promoter elements are essential as selective determinants for function of the yeast transcription factor GAL11

1996 • 15 citations

Yeast Gal11 and Transcription Factor IIE Function through a Common Pathway in Transcriptional Regulation

1997 • 15 citations

Sequences Required for Transcriptional Initiation of the Saccharomyces cerevisiae CYC7 Gene

1987 • 15 citations

Yeast Nucleotide Excision Repair Proteins Rad2 and Rad4 Interact with RNA Polymerase II Basal Transcription Factor b (TFIIH)

1994 • 11 citations

The ROX3 Gene Encodes an Essential Nuclear Protein Involved in CYC7 Gene Expression in Saccharomyces cerevisiae

1991 • 11 citations

Equivalent Mutations in the Two Repeats of Yeast TATA-Binding Protein Confer Distinct TATA Recognition Specificities

1994 • 10 citations

Positional Preferences of Polypurine/Polypyrimidine Tracts in Saccharomyces cerevisiae Genome: Implications for cis Regulation of Gene Expression

1997 • 10 citations

The CYC8 and TUP1 Proteins Involved in Glucose Repression in Saccharomyces cerevisiae Are Associated in a Protein Complex

1991 • 10 citations

Biochemical and Genetic Characterization of a Yeast TFIID Mutant That Alters Transcription In Vivo and DNA Binding In Vitro

1992 • 9 citations

MOT2 Encodes a Negative Regulator of Gene Expression That Affects Basal Expression of Pheromone-Responsive Genes in Saccharomyces cerevisiae

1994 • 9 citations

Mutational studies of yeast transcription factor IIB in vivo reveal a functional surface important for gene activation

1997 • 9 citations

Leader region of the gene encoding DNA polymerase III of Bacillus subtilis

1993 • 8 citations

A Debilitating Mutation in Transcription Factor IIE with Differential Effects on Gene Expression in Yeast

1998 • 8 citations

SHI, a New Yeast Gene Affecting the Spacing between TATA and Transcription Initiation Sites

1991 • 7 citations

The Yeast MOT2 Gene Encodes a Putative Zinc Finger Protein That Serves as a Global Negative Regulator Affecting Expression of Several Categories of Genes, Including Mating- Pheromone-Responsive Genes

1994 • 7 citations

TSF1 to TSF6, required for silencing the S. cerevisiae GAL genes are global regulatory genes

1993 • 2 citations

Deleted Work

1955 • 0 citations