The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo

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1991 • 1,023 citations

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Overview of manual and automated DNA sequencing by the dideoxy chain termination method

1991 • 840 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

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1996 • 653 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

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Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

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1994 • 473 citations

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1992 • 410 citations

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1990 • 409 citations

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Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

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Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Active repression mechanisms of eukaryotic transcription repressors

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1992 • 284 citations

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1990 • 255 citations

General requirement for RNA polymerase II holoenzymes in vivo.

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The price of repression

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TFIID binds in the minor groove of the TATA box

1991 • 206 citations

Interaction of TFIID in the minor groove of the TATA element

1991 • 170 citations

The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor.

1994 • 169 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

1996 • 158 citations

An ATP-dependent inhibitor of TBP binding to DNA.

1993 • 156 citations

Nonclassical binding of formylated peptide in crystal structure of the MHC class lb molecule H2-M3

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Mutations that suppress the deletion of an upstream activating sequence in yeast: involvement of a protein kinase and histone H3 in repressing transcription in vivo.

1993 • 144 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

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Requirement of a corepressor for Dr1-mediated repression of transcription.

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Identification and Comparison of Stable and Unstable mRNAs in Saccharomyces cerevisiae

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Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

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1996 • 107 citations

Model for binding of transcription factor TFIIB to the TBP-DNA complex

1995 • 97 citations

Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.

1996 • 97 citations

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription.

1994 • 93 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Role of Transcription Factors IIA, IID, and IIB during Formation of a Transcription-Competent Complex

1990 • 87 citations

TATA-binding Protein Residues Implicated in a Functional Interplay between Negative Cofactor NC2 (Dr1) and General Factors TFIIA and TFIIB

1995 • 76 citations

Differential Regulation of RNA Polymerases I, II, and III by the TBP-Binding Repressor Dr1

1994 • 68 citations

The Recombination Signal Sequence-Binding Protein RBP-2N Functions as a Transcriptional Repressor

1994 • 59 citations

Functional Dissection of a Human Dr1-DRAP1 Repressor Complex

1997 • 35 citations

A Negative Cofactor Containing Dr1/p19 Modulates Transcription with TFIIA in a Promoter-specific Fashion

1996 • 18 citations

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1994 • 5 citations

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1994 • 3 citations