Reversible Phosphorylation of the C-terminal Domain of RNA Polymerase II

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

RNA POLYMERASE II

1991 • 729 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation

1995 • 544 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

COMMON THEMES IN ASSEMBLY AND FUNCTION OF EUKARYOTIC TRANSCRIPTION COMPLEXES

1995 • 434 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1995 • 431 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

A kinase–cyclin pair in the RNA polymerase II holoenzyme

1995 • 418 citations

Association of Cdk-activating kinase subunits with transcription factor TFIIH

1995 • 366 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

RNA Polymerase B (II) And General Transcription Factors

1990 • 355 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.

1985 • 346 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains.

1995 • 328 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

1987 • 288 citations

Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

1995 • 280 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits transcription elongation by RNA polymerase II in vitro

1989 • 225 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

1993 • 206 citations

TheKIN28Gene is Required both for RNA Polymerase II Mediated Transcription and Phosphorylation of the Rpb1p CTD

1995 • 185 citations

Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.

1990 • 178 citations

Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

1993 • 176 citations

Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearance.

1994 • 176 citations

Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing.

1993 • 175 citations

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

1991 • 170 citations

A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID

1992 • 170 citations

Excision Repair in Mammalian Cells

1995 • 167 citations

RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals

1990 • 163 citations

Where transcription meets repair

1994 • 148 citations

Purification and characterization of a phosphatase from HeLa cells which dephosphorylates the C-terminal domain of RNA polymerase II

1994 • 137 citations

The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa.

1992 • 128 citations

RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes.

1986 • 126 citations

A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription.

1995 • 123 citations

Mutations in RNA polymerase II enhance or suppress mutations in GAL4.

1989 • 123 citations

A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.

1989 • 123 citations

The Activity of COOH-terminal Domain Phosphatase Is Regulated by a Docking Site on RNA Polymerase II and by the General Transcription Factors IIF and IIB

1995 • 121 citations

Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1991 • 117 citations

Positive patches and negative noodles: linking RNA processing to transcription?

1993 • 117 citations

The Role of Multisite Phosphorylation in the Regulation of RNA Polymerase II Activity

1994 • 100 citations

RNA polymerase II carboxy-terminal domain contributes to the response to multiple acidic activators in vitro.

1991 • 85 citations

RNA polymerases IIA and IIO have distinct roles during transcription from the TATA-less murine dihydrofolate reductase promoter.

1993 • 81 citations

Partial purification and characterization of two distinct protein kinases that differentially phosphorylate the carboxyl-terminal domain of RNA polymerase subunit IIa.

1993 • 75 citations

Interplay of positive and negative effectors in function of the C-terminal repeat domain of RNA polymerase II.

1994 • 64 citations

Subunits of Yeast RNA Polymerase II Transcription Factor TFIIH Encoded by the CCL1 Gene

1996 • 37 citations

The Photoactivated Cross-linking of Recombinant C-terminal Domain to Proteins in a HeLa Cell Transcription Extract That Comigrate with Transcription Factors IIE and IIF

1995 • 24 citations

Identification of cis-Acting Elements That Can Obviate a Requirement for the C-terminal Domain of RNA Polymerase II

1995 • 16 citations