Two Alternative Pathways of Transcription Initiation in the Yeast Negative Regulatory Gene GAL80

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

[10] Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast

1983 • 1,095 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae

1987 • 676 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Activators and targets

1990 • 582 citations

Cooperative interaction of an initiator-binding transcription initiation factor and the helix–loop–helix activator USF

1991 • 505 citations

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1991 • 497 citations

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 462 citations

Transcription by RNA polymerase II: initiator‐directed formation of transcription‐competent complexes ¹

1992 • 412 citations

Initiation of Transcription by RNA Polymerase II: A Multi-step Process

1993 • 390 citations

Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter.

1992 • 372 citations

Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae.

1985 • 342 citations

The Molecular Biology of the Yeast Saccharomyces

1983 • 329 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Transcription mechanisms and regulation

1994 • 299 citations

Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.

1982 • 280 citations

Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast

1988 • 270 citations

The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiae.

1985 • 265 citations

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex.

1992 • 265 citations

Multiple Global Regulators Control HIS4 transcription in Yeast

1987 • 246 citations

A yeast protein that influences the chromatin structure of UASG and functions as a powerful auxiliary gene activator.

1990 • 229 citations

Roles of TATA and initiator elements in determining the start site location and direction of RNA polymerase II transcription.

1992 • 229 citations

Molecular mechanisms of transcriptional regulation in yeast

1990 • 224 citations

Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression.

1991 • 211 citations

Repression versus activation in the control of gene transcription

1994 • 187 citations

Coregulation of purine and histidine biosynthesis by the transcriptional activators BAS1 and BAS2.

1992 • 187 citations

Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms.

1986 • 181 citations

An alternative pathway for transcription initiation involving TFII-I

1993 • 166 citations

A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription.

1986 • 162 citations

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.

1987 • 161 citations

The two positively acting regulatory proteins PHO2 and PHO4 physically interact with PHO5 upstream activation regions.

1989 • 160 citations

Role of trans-activating proteins in the generation of active chromatin at the PHO5 promoter in S. cerevisiae.

1990 • 143 citations

Regulatory Circuits for Gene Expression: The Metabolism of Galactose and Phosphate

1982 • 141 citations

Efficient Expression of the Saccharomyces cerevisiae PGK Gene Depends on an Upstream Activation Sequence but Does Not Require TATA Sequences

1986 • 139 citations

Nondissociation of GAL4 and GAL80 in Vivo After Galactose Induction

1992 • 139 citations

Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae

1983 • 131 citations

Overproduction of the GAL1 or GAL3 protein causes galactose-independent activation of the GAL4 protein: evidence for a new model of induction for the yeast GAL/MEL regulon.

1992 • 114 citations

In vivo DNA-binding properties of a yeast transcription activator protein.

1987 • 112 citations

GAL4 Protein: Purification, Association with GAL80 Protein, and Conserved Domain Structure

1990 • 72 citations

Nucleotide sequence of the yeast regulatory geneGAL80

1984 • 66 citations

Purification and characterization of the yeast transcriptional activator GAL4.

1990 • 66 citations

Controlled transcription of the yeast regulatory gene GAL80

1985 • 50 citations

Nucleotide sequence of the transcriptional initiation region of the yeastGAL7gene

1983 • 46 citations

Identification and purification of a protein that binds DNA cooperatively with the yeast SWI5 protein.

1993 • 45 citations

TATA-dependent and TATA-independent transcription at the HIS4 gene of yeast

1990 • 43 citations

Functional domains of a negative regulatory protein, GAL80, of Saccharomyces cerevisiae.

1989 • 42 citations

Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro.

1993 • 41 citations

Promoter Elements Determining Weak Expression of the GAL4 Regulatory Gene of Saccharomyces cerevisiae

1993 • 38 citations

Autogenous regulation on the Saccharomyces cerevisiae regulatory gene GAL80

1987 • 29 citations

Chromatin structure and regulation of the eukaryotic regulatory gene GAL80.

1993 • 16 citations

In vitro transcription of the plasma protein genes of Bombyx mori

1990 • 11 citations