Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1995 • 2,402 citations

Role of poly(ADP-ribose) formation in DNA repair

1992 • 1,142 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

Poly(ADP-Ribose) in the Cellular Response to DNA Damage

1985 • 771 citations

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

1995 • 767 citations

BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

1996 • 721 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

1995 • 600 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

ADP-ribosylation of proteins. Enzymology and biological significance.

1987 • 374 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 334 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 299 citations

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

1990 • 271 citations

The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.

1990 • 231 citations

A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

1994 • 203 citations

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

1993 • 167 citations

Purification and analysis of a factor which suppresses nick-induced transcription by RNA polymerase II and its identity with poly(ADP-ribose) polymerase.

1983 • 159 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

The Expression of Poly(ADP-ribose) Polymerase during Differentiation-Linked DNA Replication Reveals That It Is a Component of the Multiprotein DNA Replication Complex

1996 • 136 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

The human general co-factors

1996 • 105 citations

Depletion of nuclear poly(ADP-ribose) polymerase by antisense RNA expression: influences on genomic stability, chromatin organization, and carcinogen cytotoxicity.

1994 • 96 citations

Poly(ADP‐ribose) polymerase: Molecular biological aspects

1991 • 95 citations

The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapy

1995 • 92 citations

The human general co-factors

1996 • 74 citations

RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro.

1994 • 71 citations

Deletion Mutants of Poly(ADP-Ribose) Polymerase A Support a Model of Cyclic Association and Dissociation of Enzyme from DNA Ends During DNA Repair

1994 • 60 citations

Poly(ADP-ribosyl)ation, DNA strand breaks, chromatin and cancer

1993 • 42 citations

Inhibition of gene-specific repair of alkylation damage in cells deplated of poly(ADP-ribose) polymerase

1994 • 40 citations

Poly(ADP-ribose) polymerase forms loops with DNA

1987 • 39 citations

Sequence-specific transactivators counteract topoisomerase II-mediated inhibition ofin vitrotranscription by RNA polymerases I and II

1993 • 34 citations

Identification of functional targets of the Zta transcriptional activator by formation of stable preinitiation complex intermediates.

1994 • 34 citations

Growth-phase-dependent response to DNA damage in poly(ADP-ribose) polymerase deficient cell lines: basis for a new hypothesis describing the role of poly(ADP-ribose) polymerase in DNA replication and repair

1994 • 26 citations

RNA Polymerase II Cofactor PC2 Facilitates Activation of Transcription by GAL4-AH In Vitro

1994 • 21 citations

RNA polymerase II transcription control

1996 • 17 citations

Identification of Functional Targets of the Zta Transcriptional Activator by Formation of Stable Preinitiation Complex Intermediates

1994 • 11 citations