Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

[47] Establishing homologies in protein sequences

1983 • 1,187 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

RNA POLYMERASE II

1991 • 729 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

[35] Epitope tagging and protein surveillance

1991 • 526 citations

Eukaryotic RNA Polymerase

1985 • 500 citations

Glycosylation and processing of prepro-α-factor through the yeast secretory pathway

1984 • 410 citations

Prokaryotic and eukaryotic RNA polymerases have homologous core subunits.

1987 • 355 citations

Eucaryotic RNA Polymerase Conditional Mutant that Rapidly Ceases mRNA Synthesis

1987 • 353 citations

Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II

1987 • 306 citations

Inhibition of in Vivo and in Vitro Transcription by Monoclonal Antibodies Prepared against Wheat Germ RNA Polymerase II That React with the Heptapeptide Repeat of Eukaryotic RNA Polymerase II

1989 • 228 citations

Cloning of Saccharomyces cerevisiae DNA replication genes: isolation of the CDC8 gene and two genes that compensate for the cdc8-1 mutation.

1983 • 192 citations

GENETICS OF BACTERIAL RNA POLYMERASES

1979 • 192 citations

RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C

1987 • 184 citations

Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis.

1987 • 164 citations

RNA polymerase II subunit composition, stoichiometry, and phosphorylation.

1990 • 127 citations

Purification and lipid-layer crystallization of yeast RNA polymerase II.

1990 • 113 citations

Primary structure of α‐subunit of DNA‐dependent RNA polymerase from Escherichia coli

1977 • 97 citations

Subunits of RNA polymerase in function and structure

1974 • 94 citations

RNA Polymerase II Subunit RPB3 Is an Essential Component of the mRNA Transcription Apparatus

1989 • 91 citations

Reintedness of archaebacterial RNA polymerase core subunits to their eubacterial and eultaryotic equivalents

1988 • 82 citations

Conditional Mutations Occur Predominantly in Highly Conserved Residues of RNA Polymerase II Subunits

1990 • 78 citations

Active site labeling of the RNA polymerases A, B, and C from yeast.

1987 • 72 citations

Biosynthesis of RNA polymerase in Escherichia coli

1976 • 71 citations

9. Eucaryotic RNA Polymerases

1974 • 69 citations

RNA polymerase II mutants defective in transcription of a subset of genes.

1990 • 60 citations

RNA Polymerase II Subunit Composition, Stoichiometry, and Phosphorylation

1990 • 56 citations

3 Bacterial DNA-Dependent RNA Polymerases

1982 • 50 citations

A conjugation-specific gene (cnjC) fromTetrahymenaencodes a protein homologous to yeast RNA polymerase subunits (RPB3, RPC40) and similar to a portion of the prokaryotic RNA polymerase a subunit (rpoA)

1990 • 50 citations

Isolation and Characterization of Temperature-Sensitive Rna Polymerase II Mutants of Saccharomyces cerevisiae

1987 • 39 citations

Biosynthesis of RNA polymerase in Escherichia coli

1975 • 39 citations

Two related regulatory sequences are required for maximal induction of Saccharomyces cerevisiae his3 transcription.

1987 • 37 citations

Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits.

1990 • 37 citations

Defective assembly of ribonucleic acid polymerase subunits in a temperature-sensitive .alpha.-subunit mutant of Escherichia coli

1980 • 36 citations

RNA polymerase II subunit RPB3 is an essential component of the mRNA transcription apparatus.

1989 • 36 citations

The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes.

1990 • 35 citations

Conservation of a DNA-binding site in the largest subunit of eukaryotic RNA polymerase II

1983 • 33 citations

Subunits of RNA polymerase in function and structure

1976 • 27 citations

Genetic exploration of interactive domains in RNA polymerase II subunits.

1990 • 26 citations

Isolation and characterization of temperature-sensitive RNA polymerase II mutants of Saccharomyces cerevisiae.

1987 • 23 citations

RNA Polymerase II Mutants Defective in Transcription of a Subset of Genes

1990 • 23 citations

Biosynthesis of RNA polymerase in Escherichia coli

1977 • 20 citations

Genetic Exploration of Interactive Domains in RNA Polymerase II Subunits

1990 • 8 citations