Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA.

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Activators and targets

1990 • 582 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

1988 • 477 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 471 citations

COMMON THEMES IN ASSEMBLY AND FUNCTION OF EUKARYOTIC TRANSCRIPTION COMPLEXES

1995 • 434 citations

Initiation of Transcription by RNA Polymerase II: A Multi-step Process

1993 • 390 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

1995 • 374 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter.

1992 • 372 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)

1990 • 346 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

Cloning of a Transcriptionally Active Human TATA Binding Factor

1990 • 332 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

A B-cell coactivator of octamer-binding transcription factors

1995 • 301 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

Cloning, Functional Characterization, and Mechanism of Action of the B-Cell-Specific Transcriptional Coactivator OCA-B

1995 • 273 citations

A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

1992 • 272 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

The price of repression

1995 • 232 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification, Genetic Specificity, and TATA Box-Promoter Interactions of TFIID

1988 • 184 citations

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

1993 • 167 citations

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA.

1992 • 160 citations

A Class of Activation Domains Interacts Directly with TFIIA and Stimulates TFIIA-TFIID-Promoter Complex Assembly

1995 • 152 citations

Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

1994 • 151 citations

Eukaryotic coactivators associated with the TATA box binding protein

1992 • 142 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification and Analysis of Transcription Factor ILA and Identification of Transcription Factor IIJ

1992 • 136 citations

The TBP-TFIIA Interaction in the Response to Acidic Activators in Vivo

1995 • 132 citations

A general topoisomerase I-dependent transcriptional repression in the stationary phase in yeast.

1991 • 123 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA.

1993 • 108 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

Analysis of the Yeast Transcription Factor TFIIA: Distinct Functional Regions and a Polymerase II-Specific Role in Basal and Activated Transcription

1995 • 95 citations

Transcription Factor IID Mutants Defective for Interaction with Transcription Factor IIA

1992 • 95 citations

Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription.

1994 • 93 citations

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

1993 • 88 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Role of Transcription Factors IIA, IID, and IIB during Formation of a Transcription-Competent Complex

1990 • 87 citations

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

1995 • 73 citations

Phosphorylation negatively regulates the function of coactivator PC4.

1994 • 70 citations

Identification of three mammalian proteins that bind to the yeast TATA box protein TFIID.

1992 • 21 citations