YEAST TRANSCRIPTIONAL REGULATORY MECHANISMS

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

RNA POLYMERASE II

1991 • 729 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.

1994 • 547 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

Genetic Analysis of Histone H4: Essential Role of Lysines Subject to Reversible Acetylation

1990 • 346 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

Silencers, silencing, and heritable transcriptional states

1992 • 296 citations

Heme binds to a short sequence that serves a regulatory function in diverse proteins.

1995 • 285 citations

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

1993 • 283 citations

Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

1995 • 280 citations

Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding.

1995 • 276 citations

a1 Protein alters the dna binding specificity of α2 repressor

1988 • 218 citations

The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry

1990 • 215 citations

Drosophila TAF _II 150: Similarity to Yeast Gene TSM-1 and Specific Binding to Core Promoter DNA

1994 • 212 citations

The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo

1992 • 200 citations

NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

1994 • 199 citations

Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.

1992 • 186 citations

SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae.

1992 • 176 citations

ADA3, a Putative Transcriptional Adaptor, Consists of Two Separable Domains and Interacts with ADA2 and GCN5 in a Trimeric Complex

1995 • 175 citations

Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast.

1995 • 174 citations

Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity.

1994 • 162 citations

Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae.

1992 • 162 citations

Yeast and human TFIID with altered DNA-binding specificity for TATA elements

1992 • 155 citations

RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection

1994 • 155 citations

Nondissociation of GAL4 and GAL80 in Vivo After Galactose Induction

1992 • 139 citations

Structure(?) and function of acidic transcription activators

1993 • 136 citations

Characterization of sua7 mutations defines a domain of TFIIB involved in transcription start site selection in yeast.

1994 • 136 citations

REB1, a yeast DNA-binding protein with many targets, is essential for growth and bears some resemblance to the oncogene myb.

1990 • 134 citations

Functional differences between yeast and human TFIID are localized to the highly conserved region

1991 • 121 citations

Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeast

1987 • 103 citations

A highly conserved domain of TFIID displays species specificity in vivo

1991 • 97 citations

Analysis of the Yeast Transcription Factor TFIIA: Distinct Functional Regions and a Polymerase II-Specific Role in Basal and Activated Transcription

1995 • 95 citations

Mutations in the HML E silencer of Saccharomyces cerevisiae yield metastable inheritance of transcriptional repression.

1991 • 92 citations

The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations.

1994 • 83 citations

The Kin28 Protein Kinase is Associated with a Cyclin in Saccharomyces cerevisiae

1993 • 77 citations

Interaction between two homeodomain proteins is specified by a short C-terminal tail

1994 • 59 citations

Mutations on the DNA-Binding Surface of TATA-Binding Protein Can Specifically Impair the Response to Acidic Activators In Vivo

1995 • 58 citations

Negative control at a distance mediates catabolite repression in yeast

1985 • 54 citations

Binding of TFIID to the CYC1 TATA boxes in yeast occurs independently of upstream activating sequences.

1994 • 53 citations

Histones and the Regulation of Heterochromatin in Yeast

1993 • 53 citations

HAP1 positive control mutants specific for one of two binding sites.

1992 • 52 citations

The Conserved Carboxy-Terminal Domain of Saccharomyces cerevisiae TFIID Is Sufficient To Support Normal Cell Growth

1991 • 52 citations

Synergistic transcriptional enhancement does not depend on the number of acidic activation domains bound to the promoter.

1991 • 47 citations

Equivalent mutations in the two repeats of yeast TATA-binding protein confer distinct TATA recognition specificities.

1994 • 28 citations

Silencing speaks up

1994 • 26 citations