A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

RSC, an Essential, Abundant Chromatin-Remodeling Complex

1996 • 680 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila.

1988 • 460 citations

BRCA1 is a component of the RNA polymerase II holoenzyme

1997 • 450 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

A kinase–cyclin pair in the RNA polymerase II holoenzyme

1995 • 418 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1994 • 402 citations

A mediator required for activation of RNA polymerase II transcription in vitro

1991 • 383 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

1994 • 355 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

The RNA polymerase II holoenzyme and its implications for gene regulation

1995 • 297 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator.

1993 • 261 citations

TBP-TAF complexes: selectivity factors for eukaryotic transcription

1994 • 250 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization.

1996 • 200 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

Distinct TFIID complexes mediate the effect of different transcriptional activators.

1993 • 189 citations

Transcription Properties of a Cell Type–Specific TATA-Binding Protein, TRF

1997 • 170 citations

Human TAFII105 Is a Cell Type–Specific TFIID Subunit Related to hTAFII130

1996 • 169 citations

A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.

1992 • 168 citations

Mapping of Catalytic Residues in the RNA Polymerase Active Center

1996 • 162 citations

Cdc73p and Paf1p Are Found in a Novel RNA Polymerase II-Containing Complex Distinct from the Srbp-Containing Holoenzyme

1997 • 153 citations

Paf1p, an RNA Polymerase II-Associated Factor inSaccharomyces cerevisiae, May Have both Positive and Negative Roles in Transcription

1996 • 148 citations

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.

1988 • 145 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Yeast TAFII145 Required for Transcription of G1/S Cyclin Genes and Regulated by the Cellular Growth State

1997 • 143 citations

The mammalian TFIID protein is present in two functionally distinct complexes.

1991 • 142 citations

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.

1996 • 141 citations

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.

1997 • 141 citations

Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

1995 • 126 citations

Gene activation by recruitment of the RNA polymerase II holoenzyme.

1996 • 123 citations

SSNGenes That Affect Transcriptional Repression inSaccharomyces cerevisiaeEncode SIN4, ROX3, and SRB Proteins Associated with RNA Polymerase II

1996 • 117 citations

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

1995 • 114 citations

Binding of Basal Transcription Factor TFIIH to the Acidic Activation Domains of VP16 and p53

1994 • 112 citations

A Novel Collection of Accessory Factors Associated with Yeast RNA Polymerase II

1996 • 110 citations

The NOT, SPT3, and MOT1 Genes Functionally Interact To Regulate Transcription at Core Promoters

1996 • 108 citations

Evidence that Spt3 Functionally Interacts with Mot1, TFIIA, and TATA-Binding Protein To Confer Promoter-Specific Transcriptional Control in Saccharomyces cerevisiae

1997 • 104 citations

The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription.

1989 • 101 citations

Yeast homologues of higher eukaryotic TFIID subunits

1996 • 93 citations

Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila, and man

1997 • 92 citations

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.

1994 • 88 citations

Yeast Taf170 is encoded by MOT1 and exists in a TATA box-binding protein (TBP)-TBP-associated factor complex distinct from transcription factor IID.

1994 • 87 citations

Identification of Seven Hydrophobic Clusters in GCN4 Making Redundant Contributions to Transcriptional Activation

1996 • 86 citations

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

1996 • 83 citations

Different TBP-associated factors are required for mediating the stimulation of transcriptionin vitroby the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

1993 • 81 citations

The ts13 Mutation in the TAF_II250 Subunit (CCG1) of TFIID Directly Affects Transcription of D-Type Cyclin Genes in Cells Arrested in G₁ at the Nonpermissive Temperature

1997 • 81 citations

Composition of transcription factor B-TFIID.

1992 • 79 citations

TAFs: Guilt by Association?

1997 • 77 citations

Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB

1997 • 73 citations

The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae.

1991 • 70 citations

A Transcriptional Mediator Protein That Is Required for Activation of Many RNA Polymerase II Promoters and Is Conserved from Yeast to Humans

1997 • 69 citations

Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae.

1988 • 66 citations

RETRACTED: TAFIIs Mediate Activation of Transcription in the Drosophila Embryo

1996 • 64 citations

TAFIIs Mediate Activation of Transcription in theDrosophilaEmbryo

1998 • 61 citations

GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein.

1990 • 54 citations

A Presumptive Helicase (MOT1 Gene Product) Affects Gene Expression and Is Required for Viability in the Yeast Saccharomyces cerevisiae

1992 • 50 citations

Interdigitated Residues within a Small Region of VP16 Interact with Oct-1, HCF, and DNA

1997 • 49 citations

Cloning of the cDNA for the TATA-binding protein-associated factor _II 170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila

1997 • 47 citations

GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae

1988 • 43 citations

Transcriptional Corepression In Vitro: a Mot1p-Associated Form of TATA-Binding Protein Is Required for Repression by Leu3p

1996 • 41 citations

From gene to screen with yeast

1997 • 39 citations

The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo.

1995 • 39 citations

HPR1 Encodes a Global Positive Regulator of Transcription in Saccharomyces cerevisiae

1995 • 38 citations

Human TAF _II 28 interacts with the human T cell leukemia virus type I Tax transactivator and promotes its transcriptional activity

1997 • 38 citations

The Saccharomyces cerevisiae SPT13/GAL11 Gene Has Both Positive and Negative Regulatory Roles in Transcription

1989 • 34 citations

CCR4 Is a Glucose-Regulated Transcription Factor Whose Leucine-Rich Repeat Binds Several Proteins Important for Placing CCR4 in Its Proper Promoter Context

1994 • 33 citations

Expanding the Mot1 subfamily: 89B helicase encodes a new Drosophila melanogaster SNF2-related protein which binds to multiple sites on polytene chromosomes

1996 • 23 citations

The ROX3 Gene Encodes an Essential Nuclear Protein Involved in CYC7 Gene Expression in Saccharomyces cerevisiae

1991 • 11 citations