A Complex Composed of Tup1 and Ssn6 Represses Transcription in Vitro

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Tetratrico peptide repeat interactions: to TPR or not to TPR?

1995 • 624 citations

Guide to Yeast Genetics and Molecular Biology

1991 • 607 citations

COP1, an arabidopsis regulatory gene, encodes a protein with both a zinc-binding motif and a Gβ homologous domain

1992 • 587 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

Glucose repression in the yeast Saccharomyces cerevisiae

1992 • 347 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

Why does Coomassie Brilliant Blue R interact differently with different proteins? A partial answer.

1985 • 266 citations

DNA damage and cell cycle regulation of ribonucleotide reductase

1993 • 241 citations

Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities.

1989 • 240 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

The WD repeats of Tup1 interact with the homeo domain protein alpha 2.

1994 • 207 citations

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

1990 • 207 citations

A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

1988 • 197 citations

Molecular mechanisms of cell-type determination in budding yeast

1995 • 184 citations

Galactose as a gratuitous inducer of GAL gene expression in yeasts growing on glucose

1989 • 168 citations

Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae.

1993 • 146 citations

Isolation of a putative transcriptional regulator from the region of 22q11 deleted in DiGeorge syndrome, Shprintzen syndrome and familial congenital heart disease

1993 • 140 citations

The Cyc8 (Ssn6)-Tup1 Corepressor Complex Is Composed of One Cyc8 and Four Tup1 Subunits

1996 • 132 citations

The N-terminal TPR region is the functional domain of SSN6, a nuclear phosphoprotein of Saccharomyces cerevisiae.

1990 • 124 citations

Met30p, a Yeast Transcriptional Inhibitor That Responds toS-Adenosylmethionine, Is an Essential Protein with WD40 Repeats

1995 • 123 citations

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae.

1995 • 123 citations

Homeo Domain of the Yeast Repressor α2 Is a Sequence-Specific DNA-Binding Domain But Is Not Sufficient for Repression

1987 • 121 citations

A human homolog of the S.cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region

1995 • 121 citations

Transcriptional repression directed by the yeast α2 protein in vitro

1994 • 118 citations

SSNGenes That Affect Transcriptional Repression inSaccharomyces cerevisiaeEncode SIN4, ROX3, and SRB Proteins Associated with RNA Polymerase II

1996 • 117 citations

Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone

1991 • 96 citations

Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low-affinity polyclonal antibodies.

1992 • 92 citations

The tetratricopeptide repeats of Ssn6 interact with the homeo domain of alpha 2.

1995 • 90 citations

AAR1/TUP1 Protein, with a Structure Similar to That of the β Subunit of G Proteins, Is Required for a1-α2 and α2 Repression in Cell Type Control of Saccharomyces cerevisiae

1991 • 82 citations

The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family.

1995 • 80 citations

TSF3, a global regulatory protein that silences transcription of yeast GAL genes, also mediates repression by alpha 2 repressor and is identical to SIN4.

1993 • 77 citations

Three subunits of the RNA polymerase II mediator complex are involved in glucose repression

1995 • 75 citations

The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae.

1991 • 70 citations

The sulfur controller-2 negative regulatory gene of Neurospora crassa encodes a protein with beta-transducin repeats.

1995 • 58 citations

Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions

1996 • 47 citations

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