Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

1987 • 887 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer.

1989 • 432 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

1993 • 416 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast.

1992 • 284 citations

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.

1994 • 276 citations

Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions

1989 • 256 citations

TBP-TAF complexes: selectivity factors for eukaryotic transcription

1994 • 250 citations

SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo

1989 • 239 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

1994 • 203 citations

The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo

1992 • 200 citations

A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast.

1991 • 198 citations

Activator-induced conformational change in general transcription factor TFIIB

1994 • 177 citations

ADA3, a Putative Transcriptional Adaptor, Consists of Two Separable Domains and Interacts with ADA2 and GCN5 in a Trimeric Complex

1995 • 175 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein

1995 • 155 citations

A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene (CYC1) of yeast.

1985 • 144 citations

Characterization of sua7 mutations defines a domain of TFIIB involved in transcription start site selection in yeast.

1994 • 136 citations

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.

1993 • 118 citations

Structure and function of the yeast URA3 gene differentially regulated expression of hybrid β-galactosidase from overlapping coding sequences in yeast

1983 • 112 citations

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.

1994 • 109 citations

Immunopurification of yeast TATA-binding protein and associated factors. Presence of transcription factor IIIB transcriptional activity

1993 • 88 citations

HAP1 positive control mutants specific for one of two binding sites.

1992 • 52 citations

A Direct Interaction between a Glutamine-Rich Activator and the N Terminus of TFIIB Can Mediate Transcriptional Activation In Vivo

1995 • 39 citations

ADA3: A Gene, Identified by Resistance to GAL4-VP16, with Properties Similar to and Different from those of ADA2

1993 • 38 citations

SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo

1990 • 13 citations

Binding of general transcription factor TFIIB to an acidic activating region

1992 • 8 citations