The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

Analytical Properties of the Nanoelectrospray Ion Source

1996 • 1,816 citations

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

1996 • 1,687 citations

Error-Tolerant Identification of Peptides in Sequence Databases by Peptide Sequence Tags

1994 • 1,475 citations

Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels

1996 • 1,430 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.

1992 • 371 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Delayed Extraction Improves Specificity in Database Searches by Matrix-assisted Laser Desorption/Ionization Peptide Maps

1996 • 297 citations

Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity.

1996 • 266 citations

NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

1994 • 199 citations

Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry

1997 • 193 citations

IDENTIFICATION OF NEW GENES INVOLVED IN THE REGULATION OF YEAST ALCOHOL DEHYDROGENASE II

1984 • 167 citations

Dhh1p, a Putative RNA Helicase, Associates with the General Transcription Factors Pop2p and Ccr4p from Saccharomyces cerevisiae

1998 • 144 citations

Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity.

1995 • 133 citations

The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression.

1990 • 113 citations

A Novel Collection of Accessory Factors Associated with Yeast RNA Polymerase II

1996 • 110 citations

CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters.

1993 • 109 citations

Identification of a Mouse Protein Whose Homolog in Saccharomyces cerevisiae Is a Component of the CCR4 Transcriptional Regulatory Complex

1995 • 109 citations

The NOT, SPT3, and MOT1 Genes Functionally Interact To Regulate Transcription at Core Promoters

1996 • 108 citations

DBF2, a cell cycle-regulated protein kinase, is physically and functionally associated with the CCR4 transcriptional regulatory complex

1997 • 106 citations

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.

1994 • 88 citations

Molecular analysis ofPOP2gene, a gene required for glucose-derepression of gene expression inSaccharomyces cerevisiae

1992 • 64 citations

The cell-cycle-regulated budding yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle control

1991 • 64 citations

Characterization of NOT5 that encodes a new component of the Not protein complex

1998 • 63 citations

Cell biology and the genome projects a concerted strategy for characterizing multiprotein complexes by using mass spectrometry

1997 • 61 citations

The centromere and promoter factor 1, CPFI, of Saccharomyces cerevisiae modulates gene activity through a family of factors including SPT21, RPD1 (SIN3), RPD3 and CCR4

1993 • 50 citations

The products of the SPT10 and SPT21 genes of Saccharomyces cerevisiae increase the amplitude of transcriptional regulation at a large number of unlinked loci.

1991 • 46 citations

Dissection of the ADR1 protein reveals multiple, functionally redundant activation domains interspersed with inhibitory regions: evidence for a repressor binding to the ADR1^c region

1994 • 46 citations

CCR4 Is a Glucose-Regulated Transcription Factor Whose Leucine-Rich Repeat Binds Several Proteins Important for Placing CCR4 in Its Proper Promoter Context

1994 • 33 citations

Factors Affecting Saccharomyces cerevisiae ADH2Chromatin Remodeling and Transcription

1997 • 32 citations

THE EFFECT OF mei-41 ON rDNA REDUNDANCY IN DROSOPHILA MELANOGASTER

1983 • 32 citations

The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes.

1994 • 31 citations

MOT2 encodes a negative regulator of gene expression that affects basal expression of pheromone-responsive genes in Saccharomyces cerevisiae.

1994 • 29 citations

The yeast CCR4 protein is neither regulated by nor associated with the SPT6 and SPT10 proteins and forms a functionally distinct complex from that of the SNF/SWI transcription factors.

1994 • 26 citations

MOT2 Encodes a Negative Regulator of Gene Expression That Affects Basal Expression of Pheromone-Responsive Genes in Saccharomyces cerevisiae

1994 • 9 citations

Leader region of the gene encoding DNA polymerase III of Bacillus subtilis

1993 • 8 citations

The Yeast MOT2 Gene Encodes a Putative Zinc Finger Protein That Serves as a Global Negative Regulator Affecting Expression of Several Categories of Genes, Including Mating- Pheromone-Responsive Genes

1994 • 7 citations