Membrane Topology and Insertion of Membrane Proteins: Search for Topogenic Signals
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Abstract
References (220)
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Nucleotide sequence of the alkaline phosphatase gene of Escherichia coli
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Use of phoA fusions to study the topology of the Escherichia coli inner membrane protein leader peptidase
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Construction of a functional lactose permease devoid of cysteine residues
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A Reentrant Loop Domain in the Glutamate Carrier EAAT1 Participates in Substrate Binding and Translocation
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Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion.
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The topological analysis of integral cytoplasmic membrane proteins
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Insertion of the Polytopic Membrane Protein MalF Is Dependent on the Bacterial Secretion Machinery
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Cloning and Membrane Topology of a P type ATPase from Helicobacter pylori
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The Membrane Topology of GAT-1, a (Na++ Cl−)-coupled γ-Aminobutyric Acid Transporter from Rat Brain
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Forced Transmembrane Orientation of Hydrophilic Polypeptide Segments in Multispanning Membrane Proteins
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Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli.
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Properties and purification of an active biotinylated lactose permease from Escherichia coli.
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Topology of the Region Surrounding Glu681 of Human AE1 Protein, the Erythrocyte Anion Exchanger
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Membrane Topology of the Melibiose Permease ofEscherichiacoliStudied bymelB−phoAFusion Analysis
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Epitope Insertion Favors a Six Transmembrane Domain Model for the Carboxy-Terminal Portion of the Multidrug Resistance-Associated Protein
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Positively charged amino acids placed next to a signal sequence block protein translocation more efficiently in Escherichia coli than in mammalian microsomes
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Further Studies on the Properties of Liver Propionyl Coenzyme A Holocarboxylase Synthetase and the Specificity of Holocarboxylase Formation
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Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E. coli inner membrane protein proW.
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Topology of the Na+/Proline Transporter of Escherichia coli
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The Membrane Topology of the Rat Sarcoplasmic and Endoplasmic Reticulum Calcium ATPases by in Vitro Translation Scanning
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Membrane Topology of the Transposon 10-encoded Metal-Tetracycline/H+ Antiporter as Studied by Site-directed Chemical Labeling
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The use of gene fusions to examine the membrane topology of the L-subunit of the photosynthetic reaction center and of the cytochrome b subunit of the bc1 complex from Rhodobacter sphaeroides
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Membrane topography of ColE1 gene products: the immunity protein
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Topological Analysis of NhaA, a Na+/H+ Antiporter from Escherichia coli
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Stop‐transfer function of pseudo‐random amino acid segments during translocation across prokaryotic and eukaryotic membranes
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A topological analysis of subunit alpha from Escherichia coli F1F0-ATP synthase predicts eight transmembrane segments.
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Assessment of Topogenic Functions of Anticipated Transmembrane Segments of Human Band 3
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GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor.
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Use of phoA and lacZ fusions to study the membrane topology of ProW, a component of the osmoregulated ProU transport system of Escherichia coli
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Topology of NAT2, a Prototypical Example of a New Family of Amino Acid Transporters
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Mutations eliminating the protein export function of a membrane-spanning sequence.
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Membrane Topology of the C-terminal Half of the Neuronal, Glial, and Bacterial Glutamate Transporter Family
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Membrane topology of the high-affinity L-glutamate transporter (GLAST-1) of the central nervous system.
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A Mutation in the Escherichia coli secY Gene That Produces Distinct Effects on Inner Membrane Protein Insertion and Protein Export
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Molecular genetic analysis of membrane protein topology
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Topological Determinants of Internal Transmembrane Segments in P-glycoprotein Sequences
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The role of the ribosome-translocon complex in translation and assembly of polytopic membrane proteins
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Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation
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Structural Requirements for Interruption of Protein Translocation across Rough Endoplasmic Reticulum Membrane1
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Coupled Translocation Events Generate Topological Heterogeneity at the Endoplasmic Reticulum Membrane
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Purification of two active fusion proteins of the Na+‐dependent citrate carrier of Klebsiella pneumoniae
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Insertion of a Bacterial Secondary Transport Protein in the Endoplasmic Reticulum Membrane
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Chapter 10 The lactose permease of Escherichia coli: Past, present and future
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Reinitiation of Protein Translocation across the Endoplasmic Reticulum Membrane for the Topogenesis of Multispanning Membrane Proteins
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1997 • 32 citations
Site-directed Chemical Modification of Cysteine-scanning Mutants as to Transmembrane Segment II and Its Flanking Regions of the Tn10-encoded Metal-Tetracycline/H+ Antiporter Reveals a Transmembrane Water-filled Channel
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Membrane Topology of the Di- and Tripeptide Transport Protein ofLactococcus lactis
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Gene fusion analysis of membrane protein topology: a direct comparison of alkaline phosphatase and beta-lactamase fusions
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A topological model for the high‐affinity nickel transporter of Alcaligenes eutrophus
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Comparative Topology Studies in Saccharomyces cerevisiae and in Escherichia coli
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Topological analysis of the Rhodobacter capsulatus PucC protein and effects of C-terminal deletions on light-harvesting complex II
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A topological model for the general aromatic amino acid permease, AroP, of Escherichia coli
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Insertion of the Polytopic Membrane Protein Lactose Permease Occurs by Multiple Mechanisms
1995 • 27 citations
Signal sequence recognition and targeting of ribosomes to the endoplasmic reticulum by the signal recognition particle do not require GTP.
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Identification of Membrane Insertion Sequences of the Rabbit Gastric Cholecystokinin-A Receptor by in VitroTranslation
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Topology analysis of the colicin V export protein CvaA in Escherichia coli
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An amphipathic sequence determinant of membrane protein topology.
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Topological Model of the Rhodobacter capsulatus Light-Harvesting Complex I Assembly Protein LhaA (Previously Known as ORF1696)
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Position-specific Asp-Lys pairing can affect signal sequence function and membrane protein topology.
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Design of a membrane protein for site-specific proteolysis: properties of engineered factor Xa protease sites in the lactose permease of Escherichia coli
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Membrane Topology of Helixes VII and XI in the Lactose Permease of Escherichia coli Studied by lacY-phoA Fusion Analysis and Site-Directed Spectroscopy
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Topology of the phenylalanine-specific permease of Escherichia coli
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Topology and function of the Na+/proline transporter of Escherichia coli, a member of the Na+/solute cotransporter family
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Membrane topology of the L-rhamnose-H+ transport protein (RhaT) from enterobacteria.
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Transmembrane Segment (TMS) VIII of the Na+/Citrate Transporter CitS Requires Downstream TMS IX for Insertion in the Escherichia coli Membrane
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Purification and properties of the synthetase catalyzing the biotination of the aposubunit of transcarboxylase from Propionibacterium shermanii
1988 • 22 citations
Dissection of De Novo Membrane Insertion Activities of Internal Transmembrane Segments of ATP-Binding-Cassette Transporters: Toward Understanding Topological Rules for Membrane Assembly of Polytopic Membrane Proteins
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Positively charged residues influence the degree of SecA dependence in protein translocation across the E. coli inner membrane
1994 • 20 citations
Membrane topology analysis of the Escherichia coli cytosine permease
1995 • 18 citations
In Vitro Biotinylation Provides Quantitative Recovery of Highly Purified Active Lactose Permease in a Single Step
1998 • 18 citations
The Protein Translocation Apparatus Contributes to Determining the Topology of an Integral Membrane Protein in Escherichia coli
1998 • 18 citations
Introductory Lecture:In VitroTranslation Analysis of Integral Membrane Proteins
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Use of Gene Fusions to Determine Membrane Protein Topology
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Glycosylation of multiple extracytosolic loops in Band 3, a model polytopic membrane protein
1996 • 11 citations
Assembly of eukaryotic class III (N‐out, C‐in) membrane proteins into the Escherichia coli cytoplasmic membrane
1993 • 11 citations
Mechanism Involved in Generating the Carboxyl-Terminal Half Topology of P-Glycoprotein
1998 • 10 citations
Translocation of proteins across the bacterial cytoplasmic membrane
1996 • 10 citations
Chapter 32 Translocation of proteins across the bacterial cytoplasmic membrane
1996 • 5 citations
Chapter 9 Molecular genetic analysis of membrane protein topology
1996 • 4 citations
[20] Analysis of transporter topology using deletion and epitope tagging
1998 • 3 citations
The Role of Charged Amino Acids Minireview in the Localization of Secreted and Membrane Proteins
1990 • 3 citations
Deleted Work
1955 • 0 citations