Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

1996 • 2,043 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

1992 • 668 citations

Mechanism of Transport and Storage of Neurotransmitter

1987 • 471 citations

Dynamic Rearrangement of the Outer Mouth of a K+ Channel during Gating

1996 • 451 citations

The three-dimensional structure of aquaporin-1

1997 • 451 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes

1993 • 328 citations

Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

1995 • 293 citations

Three-dimensional organization of a human water channel

1997 • 278 citations

1990: Annus Mirabilis of Potassium Channels

1991 • 261 citations

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

1994 • 255 citations

Nicotinic Receptor Binding Site Probed with Unnatural Amino Acid Incorporation in Intact Cells

1995 • 227 citations

On the Use of Thiol-modifying Agents to Determine Channel Topology

1996 • 198 citations

Ion Binding and Permeation at the GABA Transporter GAT1

1996 • 188 citations

Silver as a Probe of Pore-Forming Residues in a Potassium Channel

1995 • 182 citations

Membrane Topology of the Human Na+/Glucose Cotransporter SGLT1

1996 • 164 citations

External Cysteine Residues in the Serotonin Transporter

1997 • 158 citations

Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes.

1992 • 141 citations

Listening to Neurotransmitter Transporters

1996 • 120 citations

Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution.

1993 • 112 citations

Only one of the charged amino acids located in the transmembrane alpha-helices of the gamma-aminobutyric acid transporter (subtype A) is essential for its activity.

1993 • 107 citations

Histidine 225, a Residue of the NhaA-Na+/H+ Antiporter of Escherichia coli Is Exposed and Faces the Cell Exterior

1997 • 103 citations

Methods for Expression of Excitability Proteins in Xenopus Oocytes

1994 • 99 citations

The Membrane Topology of GAT-1, a (Na++ Cl−)-coupled γ-Aminobutyric Acid Transporter from Rat Brain

1997 • 99 citations

Dopamine Transporter Cysteine Mutants: Second Extracellular Loop Cysteines Are Required for Transporter Expression

1995 • 67 citations

Analysis of the Transmembrane Topology of the Glycine Transporter GLYT1

1997 • 66 citations

Ion Channels of Excitable Cells

1994 • 63 citations

Analysis of the Transmembrane Topology and Membrane Assembly of the GAT-1 γ-Aminobutyric Acid Transporter

1997 • 32 citations