The E. coli Signal Recognition Particle Is Required for the Insertion of a Subset of Inner Membrane Proteins

Basic local alignment search tool

1990 • 87,358 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

A short course in bacterial genetics

1992 • 2,245 citations

The physical map of the whole E. coli chromosome: Application of a new strategy for rapid analysis and sorting of a large genomic library

1987 • 1,768 citations

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

1992 • 1,651 citations

Escherichia coli and Salmonella.

1996 • 1,585 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Common Principles of Protein Translocation Across Membranes

1996 • 1,081 citations

TopPred II: an improved software for membrane protein structure predictions

1994 • 954 citations

Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane

1994 • 821 citations

A Genetic Approach to Analyzing Membrane Protein Topology

1986 • 610 citations

Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle

1989 • 474 citations

Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP–binding domains

1989 • 357 citations

Azide-resistant mutants of Escherichia coli alter the SecA protein, an azide-sensitive component of the protein export machinery.

1990 • 311 citations

Determinants of membrane protein topology.

1987 • 301 citations

The signal recognition particle in S. cerevisiae

1991 • 299 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

An E. coli Ribonucleoprotein Containing 4.5 S RNA Resembles Mammalian Signal Recognition Particle

1990 • 285 citations

Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides.

1995 • 276 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

The E. coli ffh gene is necessary for viability and efficient protein export

1992 • 268 citations

An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY.

1994 • 252 citations

Effects of mutations in heat-shock genes groES and groEL on protein export in Escherichia coli.

1989 • 250 citations

Chapter 3 Analysis of Membrane Protein Topology Using Alkaline Phosphatase and β-Galactosidase Gene Fusions

1991 • 231 citations

A signal sequence is not required for protein export in prlA mutants of Escherichia coli.

1993 • 219 citations

Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor

1994 • 218 citations

E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle

1990 • 212 citations

Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases

1995 • 204 citations

Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex

1992 • 184 citations

Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain

1988 • 178 citations

Establishing Genetic Interactions by a Synthetic Dosage Lethality Phenotype

1996 • 164 citations

Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro

1981 • 126 citations

The 4.5 S RNA gene of Escherichia coli is essential for cell growth

1984 • 122 citations

The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane.

1995 • 118 citations

Ubiquitin-assisted dissection of protein transport across membranes.

1994 • 113 citations

Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog.

1993 • 109 citations

Mutations in the gene for EF-G reduce the requirement for 4.5S RNA in the growth of E. coli

1987 • 83 citations

Molecular cloning and sequencing of the gene for CDP-diglyceride hydrolase of Escherichia coli.

1985 • 82 citations

Protein translocation across the ER requires a functional GTP binding site in the alpha subunit of the signal recognition particle receptor.

1992 • 82 citations

Membrane topology analysis of Escherichia coli mannitol permease by using a nested-deletion method to create mtlA-phoA fusions.

1991 • 81 citations

A bacteriophage lambda vector for cloning with BamHI and Sau3A

1982 • 78 citations

The GTPase superfamily

1993 • 75 citations

Common structural features between eukaryotic 7SL RNAs, eubacterial 4.5S RNA and scRNA and archaebacterial 7S RNA

1988 • 69 citations

Molecular cloning and sequencing of the gene for CDP-diglyceride synthetase of Escherichia coli.

1985 • 57 citations

The Amino-terminal Charge and Core Region Hydrophobicity Interdependently Contribute to the Function of Signal Sequences

1996 • 48 citations

The dynamics of assembly of a cytoplasmic membrane protein in Escherichia coli.

1992 • 36 citations

Membrane topology model of Escherichia coli alpha-ketoglutarate permease by phoA fusion analysis

1993 • 33 citations