Mapping the Ends of Transmembrane Segments in a Polytopic Membrane Protein

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

The Kidney: Physiology and Pathophysiology

1992 • 1,714 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane.

1993 • 443 citations

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1

1994 • 419 citations

Molecular aspects of band 3 protein-mediated anion transport across the red blood cell membrane

1986 • 350 citations

Proteolytic dissection of band 3, the predominant transmembrane polypeptide of the human erythrocyte membrane

1976 • 335 citations

The complete amino acid sequence of the human erythrocyte membrane anion-transport protein deduced from the cDNA sequence

1988 • 313 citations

Cloning and characterization of band 3, the human erythrocyte anion-exchange protein (AE1).

1989 • 308 citations

The Amino Acid at the X Position of an Asn-X-Ser Sequon Is an Important Determinant of N-Linked Core-glycosylation Efficiency

1996 • 308 citations

Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase

1996 • 253 citations

lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion.

1990 • 248 citations

The Cotranslational Integration of Membrane Proteins into the Phospholipid Bilayer Is a Multistep Process

1996 • 246 citations

The role of the hydroxy amino acid in the triplet sequence Asn-Xaa-Thr(Ser) for the N-glycosylation step during glycoprotein biosynthesis

1981 • 241 citations

Molecular and cellular biology of the erythrocyte anion exchanger (AE1).

1993 • 208 citations

Structure and Function of the Red Blood Cell Anion Transport Protein

1989 • 195 citations

Molecular Biology of the Anion Exchanger Gene Family

1990 • 193 citations

Insertion of a multispanning membrane protein occurs sequentially and requires only one signal sequence

1988 • 185 citations

Translocation of proteins across the endoplasmic reticulum

1993 • 176 citations

Membrane Topology of the Human Na+/Glucose Cotransporter SGLT1

1996 • 164 citations

The Hydroxy Amino Acid in an Asn-X-Ser/Thr Sequon Can Influence N-Linked Core Glycosylation Efficiency and the Level of Expression of a Cell Surface Glycoprotein

1995 • 156 citations

A Nascent Secretory Protein 5 Traverse the Ribosome/Endoplasmic Reticulum Translocase Complex as an Extended Chain

1996 • 147 citations

Evidence for an alternate model of human P-glycoprotein structure and biogenesis.

1993 • 138 citations

Red blood cell band 3. Lysine 539 and lysine 851 react with the same H2DIDS (4,4‘-diisothiocyanodihydrostilbene-2,2‘-disulfonic acid) molecule.

1994 • 137 citations

Mapping of cystic fibrosis transmembrane conductance regulator membrane topology by glycosylation site insertion

1994 • 134 citations

Study of membrane orientation and glycosylated extracellular loops of mouse P-glycoprotein by in vitro translation.

1991 • 132 citations

Topology of the Glut 1 glucose transporter deduced from glycosylation scanning mutagenesis.

1994 • 127 citations

Monoclonal antibodies against human erythrocyte band 3 protein. Localization of proteolytic cleavage sites and stilbenedisulfonate-binding lysine residues.

1986 • 124 citations

Biogenesis of Polytopic Membrane Proteins: Membrane Segments Assemble within Translocation Channels prior to Membrane Integration

1996 • 123 citations

The intracellular targeting and membrane topology of 3-hydroxy-3-methylglutaryl-CoA reductase.

1992 • 119 citations

Asparagine-linked oligosaccharides are localized to single extracytosolic segments in multi-span membrane glycoproteins

1994 • 113 citations

Talking point Multi-spanning membrane proteins: How accurate are the models?

1988 • 107 citations

Band 3 Memphis variant II. Altered stilbene disulfonate binding and the Diego (Dia) blood group antigen are associated with the human erythrocyte band 3 mutation Pro854–>Leu.

1994 • 99 citations

Competition between folding and glycosylation in the endoplasmic reticulum.

1996 • 94 citations

Mechanisms that determine the transmembrane disposition of proteins

1992 • 87 citations

Identification of the eosinyl-5-maleimide reaction site on the human erythrocyte anion-exchange protein: overlap with the reaction sites of other chemical probes

1990 • 86 citations

The transmembrane topology of the amino terminus of the alpha subunit of the nicotinic acetylcholine receptor

1991 • 84 citations

Monoclonal antibodies to the membrane domain of the human erythrocyte anion transport protein. Localization of the C-terminus of the protein to the cytoplasmic side of the red cell membrane and distribution of the protein in some human tissues

1989 • 83 citations

Discrete Cross-linking Products Identified during Membrane Protein Biosynthesis

1997 • 82 citations

The erythrocyte anion transporter (band 3)

1993 • 80 citations

Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum.

1994 • 77 citations

Transport Processes in Eukaryotic and Prokaryotic Organisms

1996 • 67 citations

Palmitoylation of cysteine 69 from the COOH-terminal of band 3 protein in the human erythrocyte membrane. Acylation occurs in the middle of the consensus sequence of F–I-IICLAVL found in band 3 protein and G2 protein of Rift Valley fever virus.

1991 • 66 citations

Amino acid sequence of band-3 protein from rainbow trout erythrocytes derived from cDNA

1992 • 64 citations

The translocon: more than a hole in the ER membrane?

1996 • 53 citations

Localization of the carboxyl terminus of Band 3 to the cytoplasmic side of the erythrocyte membrane using antibodies raised against a synthetic peptide.

1988 • 44 citations

A structural study of the membrane domain of band 3 by tryptic digestion. Conformational change of band 3 in situ induced by alkali treatment.

1992 • 41 citations

The translocon: more than a hole in the ER membrane?

1996 • 37 citations

Erythrocyte band 3 protein: evidence for multiple membrane-crossing segments in the 17,000-dalton chymotryptic fragment

1984 • 35 citations

Complementation Studies with Co-expressed Fragments of the Human Red Cell Anion Transporter (Band 3; AE1)

1997 • 31 citations

Identification of an internal topogenic signal sequence in human Band 3, the erythrocyte anion exchanger.

1994 • 30 citations

Transmembrane Topology of the Mammalian KDEL Receptor

1993 • 24 citations

The membrane domain of the human erythrocyte anion transport protein. Epitope mapping of a monoclonal antibody defines the location of a cytoplasmic loop near the C-terminus of the protein

1990 • 24 citations

Exploration of the functional significance of the stilbene disulfonate binding site in mouse band 3 by site-directed mutagenesis

1992 • 19 citations

Topological Disposition of Tyrosine 486 in Anion Exchanger from Human Erythrocytes

1996 • 13 citations

Glycosylation of multiple extracytosolic loops in Band 3, a model polytopic membrane protein

1996 • 11 citations