Neuroendocrine Regulation of Immunity

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Brain Corticosteroid Receptor Balance in Health and Disease*

1998 • 2,442 citations

THE IL-4 RECEPTOR: Signaling Mechanisms and Biologic Functions

1999 • 1,532 citations

Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

1998 • 1,516 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Brain Corticosteroid Receptor Balance in Health and Disease

1998 • 1,138 citations

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1995 • 1,109 citations

DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

1998 • 1,081 citations

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.

1994 • 1,057 citations

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 • 972 citations

Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin

2001 • 843 citations

Characterization of Mechanisms Involved in Transrepression of NF-κB by Activated Glucocorticoid Receptors

1995 • 815 citations

Stress Hormones, Th1/Th2 patterns, Pro/Anti-inflammatory Cytokines and Susceptibility to Disease

1999 • 798 citations

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways

1999 • 785 citations

Glucocorticoids in T Cell Development and Function

2000 • 783 citations

Cytokines and the nervous system I: expression and recognition

1995 • 745 citations

Evidence for Impaired Activation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Chronic Fatigue Syndrome

1991 • 736 citations

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.

1992 • 727 citations

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.

1989 • 723 citations

Passage of Cytokines across the Blood-Brain Barrier

1995 • 718 citations

Minireview: 11β-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action¹

2001 • 712 citations

Attenuated Free Cortisol Response to Psychosocial Stress in Children with Atopic Dermatitis

1997 • 676 citations

Transcriptional Roles of Nuclear Factor κB and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor α-Dependent Induction of Cyclooxygenase-2 in MC3T3-E1 Cells

1995 • 657 citations

Tissue-Specific Dysregulation of Cortisol Metabolism in Human Obesity

2001 • 634 citations

A comparative study of the effects of an inhaled corticosteroid, budesonide, and a β2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: A randomized, double-blind, parallel-group controlled trial

1992 • 595 citations

A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

1989 • 579 citations

Cytokine-to-brain communication: A review & analysis of alternative mechanisms

1995 • 579 citations

The Human Glucocorticoid Receptor β Isoform

1996 • 553 citations

CELL CYCLE REGULATION AND APOPTOSIS

1998 • 516 citations

A Polymorphism in the Glucocorticoid Receptor Gene May Be Associated with an Increased Sensitivity to Glucocorticoidsin Vivo¹

1998 • 512 citations

Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA.

1988 • 510 citations

Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia

1994 • 506 citations

Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination

1999 • 492 citations

EFFECTS OF CORTISONE ACETATE AND PITUITARY ACTH ON RHEUMATOID ARTHRITIS, RHEUMATIC FEVER AND CERTAIN OTHER CONDITIONS

1950 • 491 citations

Vagal immune-to-brain communication: a visceral chemosensory pathway

2000 • 490 citations

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.

1995 • 487 citations

Mineralocorticoid and Glucocorticoid Receptor Activities Distinguished by Nonreceptor Factors at a Composite Response Element

1993 • 461 citations

Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance

2001 • 460 citations

The Dominant Negative Activity of the Human Glucocorticoid Receptor β Isoform

1999 • 440 citations

Catecholamine Influences and Sympathetic Neural Modulation of Immune Responsiveness

1995 • 440 citations

Association of Glucocorticoid Insensitivity with Increased Expression of Glucocorticoid Receptor β

1997 • 413 citations

The genomic structure of the human glucocorticoid receptor.

1991 • 397 citations

The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia

2000 • 392 citations

Cytokine Actions in the Central Nervous System

1998 • 373 citations

Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4

1989 • 372 citations

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

1997 • 371 citations

Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids.

1997 • 369 citations

Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?

2000 • 364 citations

Penetration of Dexamethasone into Brain Glucocorticoid Targets Is Enhanced in mdr1A P-Glycoprotein Knockout Mice*

1998 • 355 citations

Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function.

1990 • 349 citations

Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis

1992 • 341 citations

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.

1989 • 339 citations

Mechanisms of CNS response to systemic immune challenge: the febrile response

1997 • 335 citations

Transcription factors and asthma

1998 • 324 citations

GLUCOCORTICOID AND MINERALOCORTICOID RECEPTORS: Biology and Clinical Relevance

1997 • 313 citations

Nuclear Integration of Glucocorticoid Receptor and Nuclear Factor-κB Signaling by CREB-binding Protein and Steroid Receptor Coactivator-1

1998 • 307 citations

Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6

2000 • 297 citations

Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels — a comparison between Sprague-Dawley, Fischer 344 and Lewis rats

1993 • 294 citations

Increased Glucocorticoid Receptor β in Airway Cells of Glucocorticoid-insensitive Asthma

1999 • 294 citations

Endocrine markers of semistarvation in healthy lean men in a multistressor environment

2000 • 292 citations

High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy

2000 • 289 citations

Vasopressin and the regulation of hypothalamic-pituitary-adrenal axis function: Implications for the pathophysiology of depression

1998 • 279 citations

Cytokines and Sickness Behavior

1998 • 279 citations

Adrenocortical insufficiency

1985 • 270 citations

Mouse Glucocorticoid Receptor Phosphorylation Status Influences Multiple Functions of the Receptor Protein

1997 • 263 citations

Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids.

1988 • 261 citations

A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis.

2001 • 257 citations

Inhibition of Th1 Immune Response by Glucocorticoids: Dexamethasone Selectively Inhibits IL-12-Induced Stat4 Phosphorylation in T Lymphocytes

2000 • 255 citations

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids

1995 • 254 citations

Expression of glucocorticoid receptor β in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis

2000 • 251 citations

Interperson Variability but Intraperson Stability of Baseline Plasma Cortisol Concentrations, and Its Relation to Feedback Sensitivity of the Hypothalamo-Pituitary-Adrenal Axis to a Low Dose of Dexamethasone in Elderly Individuals¹

1998 • 250 citations

Steroid receptor heterodimerization demonstrated in vitro and in vivo.

1995 • 242 citations

Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance

1997 • 235 citations

Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B.

1996 • 228 citations

A Dual Mechanism Mediates Repression of NF-κB Activity by Glucocorticoids

1998 • 225 citations

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor- B and Steroid Receptor-Signaling Pathways

1999 • 215 citations

Prostaglandin E2 and Dexamethasone Inhibit IL-12 Receptor Expression and IL-12 Responsiveness

1998 • 213 citations

A genome scan localizes five non–MHC loci controlling collagen–induced arthritis in rats

1996 • 212 citations

Composite Glucocorticoid Regulation at a Functionally Defined Negative Glucocorticoid Response Element of the Human Corticotropin-Releasing Hormone Gene

1999 • 211 citations

The HIV-1 Virion-associated Protein Vpr Is a Coactivator of the Human Glucocorticoid Receptor

1999 • 210 citations

Cytokine Regulation of Neuronal Survival

1992 • 209 citations

Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis.

1992 • 208 citations

Differential Regulation of Interleukin-10 (IL-10) and IL-12 by Glucocorticoids In Vitro

1998 • 203 citations

Receptors Reconsidered: A 20-Year Perspective

1982 • 202 citations

The effects of glucocorticoids on human eosinophils

1994 • 200 citations

Stress in the brain

2000 • 188 citations

Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors

2000 • 187 citations

Use of the nuclear receptor PXR to predict drug interactions

2000 • 183 citations

Role of oestrogen receptors α and β in immune organ development and in oestrogen‐mediated effects on thymus

2001 • 182 citations

Norepinephrine: a messenger from the brain to the immune system

2000 • 181 citations

Multiple sclerosis is associated with alterations in hypothalamic-pituitary-adrenal axis function.

1994 • 175 citations

Estrogen-mediated immunosuppression in autoimmune diseases

1998 • 174 citations

Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome

1998 • 174 citations

Immunosuppression by Glucocorticoids: Inhibition of Production of Multiple Lymphokines by in Vivo Administration of Dexamethasone

1993 • 173 citations

STRAIN and sex variation in the susceptibility to streptococcal CELL WALL–INDUCED POLYARTHRITIS IN THE RAT

1982 • 170 citations

Glucocorticoid receptor localization in normal and asthmatic lung.

1996 • 167 citations

CBP (CREB Binding Protein) Integrates NF-κB (Nuclear Factor-κB) and Glucocorticoid Receptor Physical Interactions and Antagonism

2000 • 167 citations

Interleukin-1-induced long-lasting changes in hypothalamic corticotropin-releasing hormone (CRH)--neurons and hyperresponsiveness of the hypothalamus-pituitary-adrenal axis

1995 • 164 citations

NEUROENDOCRINE PERTURBATIONS IN FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME

2000 • 159 citations

Genetic dissection of systemic lupus erythematosus

1999 • 158 citations

Molecular Mechanisms of Glucocorticosteroid Actions

2000 • 158 citations

A New Function for the C-terminal Zinc Finger of the Glucocorticoid Receptor

1997 • 153 citations

Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells

1996 • 153 citations

Multiple feedback regulatory loops upon rat hypothalamic corticotropin-releasing hormone secretion. Potential clinical implications.

1988 • 150 citations

Heterodimerization between mineralocorticoid and glucocorticoid receptors increases the functional diversity of corticosteroid action

1996 • 149 citations

Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection

1999 • 149 citations

Expression of Monocyte Chemotactic Protein (MCP)-1, MCP-2, and MCP-3 by Human Airway Smooth-Muscle Cells

1999 • 147 citations

Glucocorticoid-Induced Apoptosis in Lymphocytes

2000 • 146 citations

Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids

2000 • 143 citations

Evidence That the β-Isoform of the Human Glucocorticoid Receptor Does Not Act as a Physiologically Significant Repressor

1997 • 141 citations

Glucocorticoids induce apoptosis in human monocytes: potential role of IL-1 beta.

1999 • 141 citations

Hypothalamic-pituitary-adrenocortical axis function in premenopausal women with rheumatoid arthritis not treated with glucocorticoids.

1999 • 140 citations

Thymus-derived Glucocorticoids Regulate Antigen-specific Positive Selection

1997 • 139 citations

Glucocorticoids Suppress Tumor Necrosis Factor-α Expression by Human Monocytic THP-1 Cells by Suppressing Transactivation through Adjacent NF-κB and c-Jun-Activating Transcription Factor-2 Binding Sites in the Promoter

2000 • 139 citations

The Autonomic Nervous System as a Communication Channel between the Brain and the Immune System

1995 • 133 citations

Glucocorticoids drive human CD8+ T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production

2000 • 131 citations

The pituitary gland is required for protection against lethal effects of Salmonella typhimurium.

1991 • 130 citations

An FK506-sensitive Transporter Selectively Decreases Intracellular Levels and Potency of Steroid Hormones

1996 • 125 citations

Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-κB and the glucocorticoid receptor

2000 • 124 citations

Paracrine glucocorticoid activity produced by mouse thymic epithelial cells

1999 • 123 citations

Imbalanced Expression of the Glucocorticoid Receptor Isoforms in Cultured Lymphocytes from a Patient with Systemic Glucocorticoid Resistance and Chronic Lymphocytic Leukemia

1999 • 118 citations

Intrathymic T Cell Development and Selection Proceeds Normally in the Absence of Glucocorticoid Receptor Signaling

2000 • 117 citations

Glucocorticoid modulation of human monocyte/macrophage function: Control of TNF-α secretion

1997 • 117 citations

Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague Dawley, Fischer 344, and Lewis rats

1995 • 116 citations

Evidence for arginine vasopressin as the primary activator of the HPA axis during adjuvant‐induced arthritis

1995 • 116 citations

Glucocorticoid production in the murine thymus

2000 • 112 citations

Glucocorticoid-mediated Gene Suppression of Rat Cytokine-induced Neutrophil Chemoattractant CINC/gro, a Member of the Interleukin-8 Family, through Impairment of NF-κB Activation

1996 • 111 citations

Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes

2001 • 110 citations

Hypothalamic-pituitary-adrenal axis function in patients with active rheumatoid arthritis: a controlled study using insulin hypoglycemia stress test and prolactin stimulation.

1999 • 109 citations

Macrophages and the glucocorticoids

1992 • 107 citations

Thymus-Derived Glucocorticoids Set the Thresholds for Thymocyte Selection by Inhibiting TCR-Mediated Thymocyte Activation

1999 • 106 citations

Cell cycle-dependent expression of a glioma-specific chloride current: proposed link to cytoskeletal changes

1997 • 105 citations

Tumor Necrosis Factor-α Promotes Sustained Cyclooxygenase-2 Expression: Attenuation by Dexamethasone and NSAIDs

1997 • 101 citations

Early B‐lymphocyte precursors and their regulation by sex steroids

2000 • 101 citations

Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation

1998 • 101 citations

Dexamethasone Promotes Type 2 Cytokine Production Primarily Through Inhibition of Type 1 Cytokines

2001 • 101 citations

Glucocorticoids Induce Apoptosis in Human Monocytes: Potential Role of IL-1β

1999 • 100 citations

Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans.

1996 • 99 citations

Inhibition of VCAM-1 Expression in Human Bronchial Epithelial Cells by Glucocorticoids

1999 • 99 citations

Adrenal Hormone Modulation of Type 1 and Type 2 Cytokine Production by Spleen Cells: Dexamethasone and Dehydroepiandrosterone Suppress Interleukin-2, Interleukin-4, and Interferon-γ Productionin Vitro

1998 • 97 citations

Dexamethasone Does Not Inhibit the Release of Mediators from Human Mast Cells Residing in Airway, Intestine, or Skin

1989 • 95 citations

Corticosteroid Inhibition of Airway Microvascular Leakage

1991 • 95 citations

Selective inhibition of expression of the substance P receptor mRNA in pancreatic acinar AR42J cells by glucocorticoids.

1990 • 93 citations

Hypofunction of the stress axis in Sjögren's syndrome.

1998 • 93 citations

p57Kip2, a Glucocorticoid-Induced Inhibitor of Cell Cycle Progression in HeLa Cells

1999 • 92 citations

Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells

1996 • 89 citations

The immune suppressive effect of dexamethasone in rheumatoid arthritis is accompanied by upregulation of interleukin 10 and by differential changes in interferon gamma and interleukin 4 production

1999 • 88 citations

Glucocorticoid Effects on NF-κB Binding in the Transcription of the ICAM-1 Gene

2000 • 87 citations

Sympathetic noradrenergic innervation of immune organs

1988 • 87 citations

A Dual Mechanism Mediates Repression of NF- B Activity by Glucocorticoids

1998 • 86 citations

Effects of dexamethasone on the profile of cytokine secretion in human whole blood cell cultures

1998 • 86 citations

Methyl‐Prednisolone Up‐Regulates Monocyte Interleukin‐10 Production in Stimulated Whole Blood

1999 • 86 citations

Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor α, and inhibition by glucocorticoids

1997 • 85 citations

Glucocorticoid Receptor Transcriptional Activity Determined by Spacing of Receptor and Nonreceptor DNA Sites

1998 • 85 citations

The Effect of Glucocorticoids on the Expression of L-Selectin on Polymorphonuclear Leukocyte

1999 • 84 citations

Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-κB: lack of effect of glucocorticoid receptor β

1999 • 81 citations

Plasma Cortisol Transport and Primate Evolution

1984 • 80 citations

Marked differences in functioning of the hypothalamicpituitary-adrenal axis between groups of men

1997 • 77 citations

Stress and Immunity: Implications for Viral Disease and Wound Healing

1999 • 76 citations

Role of the CD95/CD95 Ligand System in Glucocorticoid-Induced Monocyte Apoptosis

2001 • 76 citations

Hypothalamic-pituitary-adrenal axis function and prolactin secretion in systemic lupus erythematosus

1998 • 75 citations

Glucocorticoid-Induced Apoptosis and Regulation of NF-κB Activity in Human Leukemic T Cells*

1998 • 75 citations

Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking and T cell responsiveness during postnatal development.

1995 • 75 citations

Disturbed Immuno-Endocrine Communication via the Hypothalamo-Pituitary-Adrenal Axis in Autoimmune Disease

1993 • 71 citations

Disturbed Immunoendocrine Communication via the Hypothalamo–Pituitary–Adrenal Axis in Murine Lupus

1996 • 70 citations

Does differential neuroendocrine control of cytokine production govern the expression of autoimmune diseases in pregnancy and the postpartum period?

1997 • 70 citations

Glucocorticoid Receptor β: View I

1999 • 69 citations

Two Distinct Pathways of Interleukin-5 Synthesis in Allergen-Specific Human T-Cell Clones Are Suppressed by Glucocorticoids

1997 • 68 citations

DNA Binding and Bending by the Human Papillomavirus Type 16 E2 Protein

1997 • 67 citations

Regulation of the Function of Eosinophils and Basophils

1997 • 67 citations

Lipocortin 1: a second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis

1997 • 66 citations

Effect of 3 months’ nasal steroid therapy on nasal T cells and Langerhans cells in patients suffering from allergic rhinitis

1995 • 66 citations

Modulation of airway intraepithelial dendritic cells following exposure to steroids.

1995 • 66 citations

IL-4-Producing NK1.1+ T Cells Are Resistant to Glucocorticoid-Induced Apoptosis: Implications for the Th1/Th2 Balance

1998 • 65 citations

Direct Inhibitory Action of Glucocorticoid on Glycoconjugate Secretion from Airway Submucosal Glands

1990 • 64 citations

Regulation of cytokine gene expression in the central nervous system by glucocorticoids: Mechanisms and functional consequences

1997 • 64 citations

Regulation of the hypothalamo–pituitary–adrenal axis by cytokines

1999 • 64 citations

Identification of a Novel Dexamethasone-Sensitive RNA-Destabilizing Region on Rat Monocyte Chemoattractant Protein 1 mRNA

1999 • 60 citations

Pituitary-adrenal axis responsiveness to ovine corticotropin releasing hormone in patients with rheumatoid arthritis treated with low dose prednisone.

1992 • 58 citations

Glucocorticoid Suppresses Autocrine Survival of Mast Cells by Inhibiting IL-4 Production and ICAM-1 Expression

1999 • 57 citations

Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids

1997 • 56 citations

Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells

2001 • 54 citations

Induction of Interleukin-4 and Interleukin-5 Expression in Mast Cells Is Inhibited by Glucocorticoids

1998 • 53 citations

Stress-free T-cell development: glucocorticoids are not obligatory

2000 • 51 citations

NF-κB/Rel Family Members Regulating the ICAM-1 Promoter in Monocytic THP-1 Cells

1997 • 50 citations

Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human lung

1994 • 50 citations

A Positive Role for Thymus‐Derived Steroids in Formation of the T‐Cell Repertoire

1998 • 49 citations

Corticosteroid Resistance and Disease

1997 • 49 citations

Glucocorticoid Receptor β: View II

1999 • 44 citations

CBP (CREB Binding Protein) Integrates NF- B (Nuclear Factor- B) and Glucocorticoid Receptor Physical Interactions and Antagonism

2000 • 44 citations

Differential responses to stress stimuli of Lewis and Fischer rats at the pituitary and adrenocortical level.

2001 • 41 citations

Altered leucocyte trafficking and suppressed tumour necrosis factor alpha release from peripheral blood monocytes after intra-articular glucocorticoid treatment

1998 • 40 citations

Genetic Heterogeneity of Adrenocorticotropin (ACTH) Resistance Syndromes: Identification of a Novel Mutation of the ACTH Receptor Gene in Hereditary Glucocorticoid Deficiency

1998 • 40 citations

Intracerebroventricular Transplantation of Embryonic Neuronal Tissue from Inflammatory Resistant into Inflammatory Susceptible Rats Suppresses Specific Components of Inflammation

1997 • 38 citations

Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production

1999 • 38 citations

Neuroendocrine‐Immune Disturbances in Animal Models with Spontaneous Autoimmune Diseases^a

1998 • 35 citations

The importance of being receptive

1999 • 35 citations

Glucocorticoids reduce tachykinin NK2 receptor expression in bovine tracheal smooth muscle

1998 • 33 citations

Differential Mineralocorticoid (Type 1) and Glucocorticoid (Type 2) Receptor Expression in Lewis and Fischer Rats

1994 • 33 citations

Resistance to Several Steroids in Two Sisters¹

1999 • 33 citations

Identification of a novel inflammation-protective locus in the Fischer rat

1999 • 33 citations

Are lymphocytes a target for substance P modulation in arthritis?

1992 • 32 citations

Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants1These data were presented in part as an abstract at the 79th Annual Meeting of the Endocrine Society, Minneapolis, MN, June, 1997.1

1998 • 32 citations

Glucocorticoid regulation of GM-CSF: evidence for transcriptional mechanisms in airway epithelial cells

1998 • 30 citations

Lymphocyte subset responses to exercise and glucocorticoid suppression in healthy men

1996 • 27 citations

Animal models of neuroimmune interactions in inflammatory diseases

1999 • 26 citations

Human ACTH hypersensitivity syndrome associated with abnormalities of the ACTH receptor gene

1998 • 26 citations

Cytokines in the Neuroendocrine System

1998 • 25 citations

Type II 11beta-hydroxysteroid dehydrogenase expression in human colonic epithelial cells of inflammatory bowel disease.

1999 • 24 citations

Glucocorticoid‐mediated inhibition of RANTES expression in human T lymphocytes

1996 • 23 citations

Inhibition of cytoplasmic phospholipase A2 expression by glucocorticoids in rat intestinal epithelial cells

1999 • 22 citations

Multiple tandemly repeated binding sites for the YY1 repressor and transcription factors AP-1 and SP-1 are clustered within intron-1 of the gene encoding the IE110 transactivator of herpes simplex virus Type 1

1995 • 21 citations

The estrogen antagonist tamoxifen inhibits carrageenan induced inflammation in LEW/N female rats

1996 • 20 citations

The steroid resistance of Crohn's disease.

1999 • 18 citations

Lymphocyte subpopulation expression in women: effect of exercise and circadian rhythm

1997 • 17 citations

Expression of lymphocyte subsets after exercise and dexamethasone in high and low stress responders

1999 • 17 citations

Isolated Glucocorticoid Deficiency and ACTH Receptor Mutations

1999 • 16 citations

A Case of Isolated ACTH Deficiency Who Developed Autoimmune-Mediated Hypothyroidism and Impaired Water Diuresis during Glucocorticoid Replacement Therapy.

2000 • 10 citations

Mutations of the ACTH Receptor Gene in a New Family with Isolated Glucocorticoid Deficiency

2000 • 10 citations