Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection

Biologic basis for interleukin-1 in disease

1996 • 4,324 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Immune-Neuro-Endocrine Interactions: Facts and Hypotheses

1996 • 1,477 citations

The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions

1997 • 827 citations

Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection.

1996 • 413 citations

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

1996 • 384 citations

Differential regulation of lipopolysaccharide‐induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary‐adrenal axis

1989 • 328 citations

Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor.

1988 • 295 citations

The role of IFN-gamma in the pathology of experimental endotoxemia.

1990 • 257 citations

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction.

1994 • 235 citations

Response to local inflammation of IL-1 beta-converting enzyme- deficient mice.

1997 • 235 citations

Characterization of Early Cytokine Responses and an Interleukin (IL)-6–dependent Pathway of Endogenous Glucocorticoid Induction during Murine Cytomegalovirus Infection

1997 • 212 citations

Adrenalectomy enhances pro-inflammatory cytokines gene expression, in the spleen, pituitary and brain of mice in response to lipopolysaccharide

1996 • 126 citations

Neuroendocrine regulation of cytokine production during experimental influenza viral infection: effects of restraint stress-induced elevation in endogenous corticosterone.

1996 • 106 citations

The Protective Role of the Hypothalamic‐Pituitary‐Adrenal Axis against Lethality Produced by Immune, Infectious, and Inflammatory Stress

1995 • 106 citations

Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function.

1996 • 105 citations

Participation of endogenous tumour necrosis factor in host resistance to cytomegalovirus infection

1993 • 103 citations

Mechanisms for virus-induced liver disease: tumor necrosis factor-mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection

1997 • 95 citations

Stress-induced glucocorticoid response modulates mononuclear cell trafficking during an experimental influenza viral infection

1995 • 85 citations

Gene expression and secretion of cytokines and cytokine receptors from highly purified CD56⁺ natural killer cells stimulated with interleukin‐2, interleukin‐7 and interleukin‐12

1993 • 77 citations

Interleukin‐12 activates human γδ T cells: synergistic effect of tumor necrosis factor‐α

1996 • 54 citations

Influence of endogenous glucocorticoid on endotoxin-induced production of circulating TNF-alpha.

1991 • 52 citations

Effects of viral infection on corticosterone secretion and glucocorticoid receptor binding in immune tissues

1997 • 46 citations

Interleukin-1 Receptor Antibody (IL-1rab) Protection and Treatment against Lethal Endotoxemia in Mice

1993 • 35 citations

Adrenalitis and the adrenocortical response of resistant and susceptible mice to acute murine cytomegalovirus infection

1996 • 29 citations

Effects of tumor necrosis factor-α treatment on mortality in murine cytomegalovirus-infected mice

1993 • 11 citations

The influence of endogenous hypocorticism on the replication of influenza virus in the mouse lungs and the production of specific antibodies.

1990 • 4 citations