Identification of a Novel Dexamethasone-Sensitive RNA-Destabilizing Region on Rat Monocyte Chemoattractant Protein 1 mRNA

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

On Finding All Suboptimal Foldings of an RNA Molecule

1989 • 2,019 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells.

1990 • 1,147 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

A workbench for multiple alignment construction and analysis

1991 • 1,005 citations

Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation.

1984 • 994 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Monocyte chemoattractant protein-1 in human atheromatous plaques.

1991 • 892 citations

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

1991 • 879 citations

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1996 • 858 citations

Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates

1993 • 762 citations

Human monocyte chemoattractant protein-1 (MCP-1)

1990 • 666 citations

Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1989 • 593 citations

Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.

1995 • 556 citations

Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.

1990 • 500 citations

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.

1989 • 497 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

Interstitial Collagenase (MMP-1) Expression in Human Carotid Atherosclerosis

1995 • 402 citations

The Endotoxin‐induced Coagulant Activity of Human Monocytes

1975 • 382 citations

Cytokines Regulate Vascular Functions Related to Stability of the Atherosclerotic Plaque

1995 • 374 citations

Regulation of cytokine and cytokine receptor expression by glucocorticoids

1996 • 326 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

mRNA Decay Mediated by Two Distinct AU-Rich Elements from c-fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

1995 • 276 citations

Regulation of the tissue factor gene

1995 • 275 citations

Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

1993 • 272 citations

Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)

1989 • 266 citations

Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts

1992 • 263 citations

Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture

1988 • 263 citations

Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells

1989 • 247 citations

The Human Homolog of the JE Gene Encodes a Monocyte Secretory Protein

1989 • 227 citations

Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates.

1992 • 223 citations

Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.

1987 • 217 citations

Inhibition by glucocorticoids of the formation of interleukin-1 alpha, interleukin-1 beta, and interleukin-6: mediation by decreased mRNA stability.

1993 • 202 citations

Detection and Characterization of a 3′ Untranslated Region Ribonucleoprotein Complex Associated with Human α-Globin mRNA Stability

1995 • 194 citations

In situ localization of tissue factor in human atherosclerotic plaques by binding of digoxigenin-labeled factors VIIa and X.

1996 • 194 citations

Cytokines and growth factors in atherogenesis.

1992 • 183 citations

MCP-1 expression by rat type II alveolar epithelial cells in primary culture.

1993 • 161 citations

Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression.

1989 • 154 citations

Agonist-mediated tissue factor expression in cultured vascular smooth muscle cells. Role of Ca2+ mobilization and protein kinase C activation.

1993 • 150 citations

JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells.

1992 • 147 citations

Monocyte Chemoattractant Protein-1 (MCP-1) in Inflammatory Joint Diseases and Its Involvement in the Cytokine Network of Rheumatoid Synovium

1993 • 133 citations

The effects of dexamethasone on in vitro collagen gene expression.

1987 • 128 citations

Identification of foam cells in human atherosclerotic lesions as macrophages using monoclonal antibodies.

1985 • 122 citations

An A+U-Rich Element RNA-Binding Factor Regulates c-myc mRNA Stability In Vitro

1991 • 121 citations

The effect of glucocorticoids on proliferation of human cultured airway smooth muscle

1995 • 112 citations

Dexamethasone inhibits the induction of monocyte chemotactic-activating factor production by IL-1 or tumor necrosis factor.

1991 • 110 citations

Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.

1986 • 97 citations

Two cellular proteins bind specifically to a purine-rich sequence necessary for the destabilization function of a c-fos protein-coding region determinant of mRNA instability.

1992 • 81 citations

An amino-terminal tetrapeptide specifies cotranslational degradation of beta-tubulin but not alpha-tubulin mRNAs.

1994 • 78 citations

Poly(A) Shortening and Degradation of the 3′ A+U-Rich Sequences of Human c-myc mRNA in a Cell-Free System

1988 • 71 citations

Purification and Characterization of an Estrogen-regulated Xenopus Liver Polysomal Nuclease Involved in the Selective Destabilization of Albumin mRNA

1995 • 65 citations

Glucocorticoids inhibit the transcriptional induction of JE, a platelet-derived growth factor-inducible gene

1991 • 63 citations

Secretion of monocyte chemotactic activity by cultured rat aortic smooth muscle cells in response to PDGF is due predominantly to the induction of JE/MCP-1.

1996 • 63 citations

Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells.

1993 • 62 citations

In vivo and in vitro inhibition of JE gene expression by glucocorticoids.

1991 • 59 citations

Glucocorticoid inhibition of vascular smooth muscle cell proliferation: influence of homologous extracellular matrix and serum mitogens.

1984 • 59 citations

Glucocorticoids inhibit chemokine generation by human eosinophils

1998 • 59 citations

Anti-inflammatory mechanisms of glucocorticoids

1995 • 58 citations

Dexamethasone inhibits macrophage accumulation after balloon arterial injury in cholesterol fed rabbits

2001 • 56 citations

Dexamethasone Inhibits Insulin Biosynthesis by Destabilizing Insulin Messenger Ribonucleic Acid in Hamster Insulinoma Cells

1990 • 50 citations

Expression of monocyte chemoattractant protein-1 in meningioma

1995 • 47 citations

Effects of Dexamethasone on Experimental Atherosclerosis in Cholesterol-fed Rabbits.

1992 • 38 citations

Dexamethasone Suppresses Vascular Smooth Muscle Cell Proliferation

1999 • 37 citations

Post-transcriptional control of c-myc proto-oncogene expression by glucocorticoid hormones in human T lymphoblastic leukemic cells

1990 • 31 citations

Differential regulation of chemokines by leukemia inhibitory factor, interleukin-6 and oncostatin M

1997 • 31 citations

Steroid Effects on Protein Synthesis in Cultured Smooth Muscle Cells from Rat Aorta*

1983 • 28 citations

Two Cellular Proteins Bind Specifically to a Purine-Rich Sequence Necessary for the Destabilization Function of a c-fos Protein-Coding Region Determinant of mRNA Instability

1992 • 26 citations

An Amino-Terminal Tetrapeptide Specifies Cotranslational Degradation of β-Tubulin but Not α-Tubulin mRNAs

1994 • 22 citations

Platelet-derived Growth Factor-specific Regulation of theJE Promoter in Rat Aortic Smooth Muscle Cells

1998 • 21 citations

The estrogen-regulated destabilization of Xenopus albumin mRNA is independent of translation

1991 • 11 citations

Exonuclease activity that degrades histone mRNA is stable when DNA or protein synthesis is inhibited.

1989 • 8 citations