Role of oestrogen receptors α and β in immune organ development and in oestrogen‐mediated effects on thymus

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Human Estrogen Receptor β-Gene Structure, Chromosomal Localization, and Expression Pattern1

1997 • 1,098 citations

Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse

1997 • 968 citations

Estrogen Receptors α and β Form Heterodimers on DNA

1997 • 681 citations

Mouse Estrogen Receptor β Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor α

1997 • 610 citations

Human Estrogen Receptor -Gene Structure, Chromosomal Localization, and Expression Pattern

1997 • 576 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice

2000 • 389 citations

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

1996 • 371 citations

Radioimmunoassays for IGFs and IGFBPs.

1994 • 367 citations

Age and sex associations of 40 autoimmune diseases

1994 • 355 citations

Tissue Distribution of Estrogen Receptors Alpha (ER-α) and Beta (ER-β) mRNA in the Midgestational Human Fetus

1997 • 329 citations

The Somatogenic Hormones and Insulin-Like Growth Factor-1: Stimulators of Lymphopoiesis and Immune Function

1997 • 300 citations

Sex steroid regulation of autoimmunity

1991 • 207 citations

Mouse Estrogen Receptor Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor

1997 • 203 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

1995 • 187 citations

The Role of Estrogen Receptors and Androgen Receptors in Sex Steroid Regulation of B Lymphopoiesis

1998 • 183 citations

Estrogen receptor alpha is necessary in thymic development and estradiol-induced thymic alterations.

1999 • 180 citations

Expression and Localization of Estrogen Receptor-β in Murine and Human Bone

1999 • 169 citations

Estrogen Blocks Early T Cell Development in the Thymus

1996 • 167 citations

Estrogen suppresses stromal cell-dependent lymphopoiesis in culture.

1995 • 151 citations

Enhancement of tumor metastasis and suppression of natural killer cell activity by beta-estradiol treatment.

1983 • 147 citations

Oestrogen is a potent disease accelerator in SLE-prone MRL lpr/lpr mice

1990 • 145 citations

Involution of the mammalian thymus, one of the leading regulators of aging.

1998 • 143 citations

Estrogen Receptor α Is Necessary in Thymic Development and Estradiol-Induced Thymic Alterations

1999 • 143 citations

Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cells.

1992 • 142 citations

The thymus in pregnancy: the interplay of neural, endocrine and immune influences

1994 • 142 citations

Anti-inflammatory properties of estrogen

1992 • 140 citations

Differential effects of growth hormone and prolactin on murine T cell development and function.

1993 • 136 citations

Estrogen Induces Suppression of Natural Killer Cell Cytotoxicity and Augmentation of Polyclonal B Cell Activation

1994 • 115 citations

Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cells

1992 • 98 citations

Oestradiol- and testosterone-mediated effects on the immune system in normal and autoimmune mice are genetically linked and inherited as dominant traits.

1989 • 96 citations

In vivo effects of growth hormone on thymus function in aging mice

1992 • 89 citations

Disproportional Body Growth in Female Estrogen Receptor-α-Inactivated Mice

1999 • 89 citations

Tissue Distribution of Estrogen Receptors Alpha (ER- ) and Beta (ER- ) mRNA in the Midgestational Human Fetus

1997 • 89 citations

Estrogen Receptor-β Messenger Ribonucleic Acid Expression in the Pituitary Gland**This material is based on work supported by the NSF (96–04723; RJH) and USHPS National Research Scientist Award Predoctoral Fellowships F31-AA05395 (to M.E.W.) and F31-AA05461 (to R.H.P.).

1998 • 80 citations

Involvement of Insulin-Like Growth Factors in Early T Cell Development: A Study Using Fetal Thymic Organ Cultures¹

2000 • 79 citations

The role of growth hormone and insulin-like growth factors in the immune system

1998 • 76 citations

Sex Hormones and the Thymus in Relation to Thymocyte Proliferation and Maturation.

1997 • 62 citations

Estrogen and antiestrogen modulation of the levels of mouse natural killer activity and large granular lymphocytes

1987 • 61 citations

Sex steroids induce apoptosis of CD8+CD4+ double-positive thymocytes via TNF-α

2000 • 56 citations

Estrogen Receptor- Messenger Ribonucleic Acid Expression in the Pituitary Gland

1998 • 32 citations

Effects of Castration, Depo‐Testosterone and Cyproterone Acetate on Lymphocyte T Subsets in Mouse Thymus and Spleen

1991 • 32 citations

Growth allometry of organs, muscles and bones in mice from lines divergently selected on the basis of plasma insulin-like growth factor-I.

1992 • 29 citations

In Vivo Effect of Progesteron and Estrogen on Thymus Mass and T-Cell Functions in Female Mice

1984 • 26 citations

Effects of growth hormone on growth and muscle Na(+)-K+ pump concentration in K(+)-deficient rats

1992 • 15 citations