Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells

Molecular Cloning: A Laboratory Manual

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Molecular cloning: A laboratory manual

1990 • 85,659 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Diversity of group types, regulation, and function of phospholipase A2.

1994 • 1,444 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

New insights into the mode of action of anti-inflammatory drugs

1995 • 853 citations

Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid

1989 • 542 citations

Structure of the human cyclo-oxygenase-2 gene

1994 • 488 citations

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.

1990 • 484 citations

Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.

1994 • 478 citations

Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.

1994 • 423 citations

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1988 • 406 citations

Characterization of the human gene (PTGS2) encoding prostaglandin‐endoperoxide synthase 2

1994 • 396 citations

Cyclooxygenase-2: Regulation and relevance in inflammation

1995 • 368 citations

Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme

1989 • 333 citations

Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone

1994 • 311 citations

Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes.

1994 • 310 citations

Characterization of the Genomic Structure, Chromosomal Location and Promoter of Human Prostaglandin H Synthase-2 Gene

1994 • 272 citations

Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis factor

1993 • 253 citations

Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B.

1996 • 228 citations

Expression of cyclooxygenase types 1 and 2 in human fetal membranes at term

1995 • 161 citations

Suppression of monocyte 85-kDa phospholipase A2 by antisense and effects on endotoxin-induced prostaglandin biosynthesis

1994 • 116 citations

The potential role of tumour necrosis factor a in asthma

1993 • 115 citations

Interleukin‐1‐Induced Prostaglandin E₂ Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A₂ and Cyclooxygenase‐2

1994 • 108 citations

Cyclooxygenase gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells.

1991 • 83 citations

Superinduction of NF-κB by Actinomycin D and Cycloheximide in Epithelial Cells

1996 • 83 citations

Interleukin-1-Induced Prostaglandin E2 Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A2 and Cyclooxygenase-2

1994 • 76 citations

The Relative Abundance of Type 1 to Type 2 Cyclo-oxygenase mRNA in Human Amnion at Term

1994 • 64 citations

Cytosolic phospholipase A2 gene expression in rat mesangial cells is regulated post-transcriptionally

1994 • 37 citations

The Role of Cytokines in Asthma

1991 • 21 citations