Multiple sclerosis is associated with alterations in hypothalamic-pituitary-adrenal axis function.

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease

1986 • 773 citations

Evidence for Impaired Activation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Chronic Fatigue Syndrome

1991 • 736 citations

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.

1989 • 723 citations

A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

1989 • 579 citations

The Effect of Corticosteroids for Acute Optic Neuritis on the Subsequent Development of Multiple Sclerosis

1993 • 572 citations

Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.

1989 • 339 citations

Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis

1991 • 330 citations

Cytokine accumulations in CSF of multiple sclerosis patients

1990 • 270 citations

Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system.

1988 • 229 citations

The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat.

1990 • 201 citations

Arginine vasopressin potentiates adrenocorticotropin release induced by ovine corticotropin-releasing factor.

1984 • 191 citations

Long-lasting hormonal alterations to extreme stress in humans: normative or maladaptive?

1993 • 130 citations

Vasopressin stimulates cortisol secretion from human adrenocortical tissue through activation of V1 receptors.

1993 • 103 citations

Adrenal Cortical Response to Stress at Three Mile Island

1984 • 102 citations

The Cellular Actions of Vasopressin on Corticotrophs of the Anterior Pituitary: Resistance to Glucocorticoid Action

1987 • 88 citations

Adrenal Size Is Increased in Multiple Sclerosis

1994 • 81 citations

Dexamethasone suppression test abnormalities in multiple sclerosis: Relation to ACTH therapy

1987 • 57 citations

ENDOCRINE ACTIVITY IN MULTIPLE SCLEROSIS

1967 • 22 citations

Endocrine function in multiple sclerosis

2009 • 22 citations