The Steroid and Thyroid Hormone Receptor Superfamily

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Sequence and Expression of Human Estrogen Receptor Complementary DNA

1986 • 1,321 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Identification of a new class of steroid hormone receptors

1988 • 845 citations

Zinc fingers: Gilt by association

1988 • 799 citations

Mechanism of Action of the Female Sex Hormones

1972 • 763 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.

1986 • 733 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

1983 • 619 citations

Genetic Switch

2008 • 590 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Molecular Cloning of Complementary DNA Encoding the Avian Receptor for Vitamin D

1987 • 516 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

Feeding Experiments on tadpoles

1912 • 430 citations

Identification of a Novel Thyroid Hormone Receptor Expressed in the Mammalian Central Nervous System

1987 • 429 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

On the constitutional and local effects of disease of the supra-renal capsules

1855 • 423 citations

Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA

1987 • 419 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma

1986 • 399 citations

Comparative Vertebrate Endocrinology

1998 • 392 citations

The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.

1986 • 392 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY¹

1972 • 336 citations

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

1987 • 324 citations

Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression.

1982 • 304 citations

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

1987 • 299 citations

Glucocorticoid toxicity in the hippocampus: reversal by supplementation with brain fuels

1986 • 288 citations

Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action

1975 • 284 citations

Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids

1981 • 284 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.

1982 • 280 citations

Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis.

1978 • 258 citations

A Novel Thyroid Hormone Receptor Encoded by a cDNA Clone from a Human Testis Library

1987 • 242 citations

Purification of the glucocorticoid receptor from rat liver cytosol.

1979 • 239 citations

The chicken progesterone receptor: sequence, expression and functional analysis.

1987 • 236 citations

Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene.

1985 • 235 citations

Steroid Hormone Regulation of Gene Expression

1985 • 228 citations

The glucocorticoid domain: Steroid-mediated changes in the rate of synthesis of rat hepatoma proteins

1978 • 227 citations

42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter

1987 • 220 citations

Regulated expression of human growth hormone genes in mouse cells

1982 • 219 citations

Molecular cloning of gene sequences transcriptionally regulated by retinoic acid and dibutyryl cyclic AMP in cultured mouse teratocarcinoma cells

1985 • 215 citations

Cloning and sequence analysis of rabbit progesterone-receptor complementary DNA.

1986 • 204 citations

Genetic Approaches to Steroid Hormone Action

1976 • 203 citations

Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response

1980 • 186 citations

Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

1984 • 186 citations

THE ISOLATION IN CRYSTALLINE FORM OF THE COMPOUND CONTAINING IODIN, WHICH OCCURS IN THE THYROID

1915 • 186 citations

Steroid-free glucocorticoid receptor binds specifically to mouse mammary tumour virus DNA

1986 • 185 citations

Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region

1982 • 181 citations

Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

1982 • 178 citations

Domains of the Glucocorticoid Receptor Involved in Specific and Nonspecific Deoxyribonucleic Acid Binding, Hormone Activation, and Transcriptional Enhancement

1987 • 174 citations

A Single Domain of the Estrogen Receptor Confers Deoxyribonucleic Acid Binding and Transcriptional Activation of the Rat Prolactin Gene

1988 • 173 citations

Stimulation of differentiation of several murine embryonal carcinoma cell lines by retinoic acid

1979 • 165 citations

TheXenopus laevisEstrogen Receptor: Sequence Homology with Human and Avian Receptors and Identification of Multiple Estrogen Receptor Messenger Ribonucleic Acids*

1987 • 159 citations

Dexamethasone Stimulation of Murine Mammary Tumor Virus Expression: A Tissue Culture Source of Virus

1974 • 152 citations

DNA sequence preference of the progesterone receptor.

1983 • 150 citations

Purified glucocorticoid receptor-hormone complex from rat liver cytosol binds specifically to cloned mouse mammary tumor virus long terminal repeats in vitro.

1982 • 147 citations

Promoter Elements of Genes Coding for Proteins and Modulation of Transcription by Estrogens and Progesterone

1984 • 133 citations

Sequence and Expression of a Functional Chicken Progesterone Receptor

1987 • 112 citations

Sequencing the erb A Gene of Avian Erythroblastosis Virus Reveals a New Type of Oncogene

1984 • 111 citations

Structure of the chromosomal chicken progesterone receptor gene.

1987 • 108 citations

Multihormonal induction of hepatic α _2u -globulin mRNA as measured by hybridization to complementary DNA

1977 • 92 citations

Active domains in wild-type and mutant glucocorticoid receptors.

1982 • 78 citations

Modulation of enhancer activity by the hormone responsive regulatory element from mouse mammary tumor virus.

1984 • 74 citations

Characterization of an antiserum against the glucocorticoid receptor

1981 • 69 citations

The binding activity of estrogen receptor to DNA and heat shock protein (Mr 90,000) is dependent on receptor-bound metal.

1987 • 66 citations

Steroid Hormone Receptors in Human Breast Cancer

1983 • 66 citations

Towards a biochemistry of morphogenesis

1987 • 65 citations

Introduction of estrogen-responsiveness into mammalian cell lines

1986 • 64 citations

A method for the simultaneous alignment of three or more amino acid sequences

1986 • 64 citations

The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2.

1987 • 62 citations

Thyroid and Temperature in Cold-blooded Vertebrates

1929 • 25 citations

Chromosomal action of ecdysone

1980 • 20 citations

Pesticides: FDA told to try harder

1986 • 1 citations