Type II 11beta-hydroxysteroid dehydrogenase expression in human colonic epithelial cells of inflammatory bowel disease.

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR

1988 • 1,047 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

Increased Intestinal Permeability in Patients with Crohn's Disease and Their Relatives

1986 • 731 citations

Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

1994 • 707 citations

THE COLONIC EPITHELIUM IN ULCERATIVE COLITIS: AN ENERGY-DEFICIENCY DISEASE?

1980 • 678 citations

Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity.

1983 • 515 citations

THE VALUE OF RECTAL BIOPSY IN THE DIAGNOSIS OF ULCERATIVE COLITIS<sup>1</sup>

1961 • 318 citations

Expression of class II molecules on intestinal epithelial cells in humans

1991 • 279 citations

Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells

1993 • 196 citations

Cellular basis for defective electrolyte transport in inflamed human colon

1990 • 164 citations

Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent

1995 • 148 citations

Electrolyte transport across colonic mucosa from patients with inflammatory bowel disease

1980 • 147 citations

Substance P enhances IL-2 expression in activated human T cells.

1992 • 145 citations

Autoimmunity to cytoskeletal protein tropomyosin. A clue to the pathogenetic mechanism for ulcerative colitis.

1993 • 144 citations

Epithelial Cell Renewal in Cultured Rectal Biopsies in Ulcerative Colitis

1973 • 144 citations

Effect of d-Aldosterone on Salt and Water Absorption from the Intact Human Colon*

1965 • 136 citations

Localization of 11 beta-hydroxysteroid dehydrogenase type II in human epithelial tissues.

1996 • 129 citations

Interleukin 8 secretion by colonic crypt cells in vitro: response to injury suppressed by butyrate and enhanced in inflammatory bowel disease.

1995 • 108 citations

Colocalization of 11β-Hydroxysteroid Dehydrogenase Type II and Mineralocorticoid Receptor in Human Epithelia

1997 • 84 citations

Changes in neuropeptide‐containing nerves in human colonic mucosa with inflammatory bowel disease

1994 • 81 citations

Crypt cell production rate in ulcerative proctocolitis: differential increments in remission and relapse.

1985 • 68 citations

Corticosteroids and intestinal ion transport

1987 • 62 citations

Effects of inflammatory mediators on electrolyte transport across the porcine distal colon epithelium.

1993 • 43 citations

Energy level in large intestinal mucosa in patients with ulcerative colitis.

1984 • 43 citations

Sodium butyrate-induced liver-type alkaline phosphatase activity in a small intestinal epithelial cell line, IEC6.

1998 • 29 citations

Pharmacological basis of contractile effects of peptidoleukotrienes on rabbit colonic muscularis mucosae

1993 • 13 citations