Multiple tandemly repeated binding sites for the YY1 repressor and transcription factors AP-1 and SP-1 are clustered within intron-1 of the gene encoding the IE110 transactivator of herpes simplex virus Type 1

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1984 • 567 citations

YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro

1991 • 465 citations

The serum response element

1992 • 458 citations

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

1981 • 449 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

Isolation and Characterization of a Herpes Simplex Virus Type 1 Mutant Containing a Deletion within the Gene Encoding the Immediate Early Polypeptide Vmw110

1986 • 422 citations

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity.

1984 • 396 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency

1989 • 372 citations

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

1988 • 360 citations

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

1991 • 357 citations

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1985 • 345 citations

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

1987 • 333 citations

Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.

1993 • 310 citations

Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein.

1991 • 303 citations

Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation

1985 • 285 citations

Interaction between transcription factors Spl and YY1

1993 • 282 citations

Differential Expression of c- myb mRNA in Murine B Lymphomas by a Block to Transcription Elongation

1987 • 279 citations

Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene.

1985 • 267 citations

Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus.

1992 • 251 citations

Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.

1985 • 242 citations

Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA

1989 • 237 citations

DNA bending and orientation-dependent function of YY1 in the c-fos promoter.

1993 • 233 citations

The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency

1993 • 233 citations

Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.

1990 • 227 citations

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts.

1992 • 221 citations

Homology between mammalian cell DNA sequences and human herpesvirus genomes detected by a hybridization procedure with high-complexity probe

1982 • 220 citations

Characterization of the IE110 Gene of Herpes Simplex Virus Type 1

1986 • 192 citations

Yin-yang 1 activates the c-myc promoter.

1993 • 187 citations

Functional antagonism between YY1 and the serum response factor.

1992 • 168 citations

Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor

1989 • 167 citations

Comparative Sequence Analysis of the Long Repeat Regions and Adjoining Parts of the Long Unique Regions in the Genomes of Herpes Simplex Viruses Types 1 and 2

1991 • 150 citations

Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.

1992 • 142 citations

Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system

1989 • 132 citations

Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production

1994 • 123 citations

Transcriptional and post-transcriptional controls establish the cascade of herpes simplex virus protein synthesis

1987 • 118 citations

Herpesvirus Transcription and Its Regulation

1991 • 118 citations

Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III

1989 • 114 citations

A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1

1991 • 114 citations

A Truncated Form of Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Is Expressed in a Cell Type Dependent Manner

1993 • 104 citations

Reactivation of latent herpes simplex virus by adenovirus recombinants encoding mutant IE-0 gene products

1990 • 95 citations

Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10)

1989 • 93 citations

Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis

1993 • 86 citations

A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1 genome

1993 • 86 citations

YY1 represses beta-casein gene expression by preventing the formation of a lactation-associated complex.

1994 • 84 citations

Herpes Simplex Virus Genes Involved in Latency in vitro

1987 • 78 citations

Protein-DNA interactions in the epsilon-globin gene silencer.

1993 • 76 citations

Negative regulation of the BZLF1 promoter of Epstein-Barr virus

1991 • 74 citations

Activation of second-messenger pathways reactivates latent herpes simplex virus in neuronal cultures

1992 • 71 citations

Identification of immediate-early-type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2

1989 • 71 citations

Expression from the murine p53 promoter is mediated by factor binding to a downstream helix-loop-helix recognition motif.

1991 • 67 citations

The Intracisternal A-Particle Upstream Element Interacts with Transcription Factor YY1 To Activate Transcription: Pleiotropic Effects of YY1 on Distinct DNA Promoter Elements

1993 • 62 citations

The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection

1993 • 58 citations

Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region

1993 • 57 citations

Mapping of intracellular localization domains and evidence for colocalization interactions between the IE110 and IE175 nuclear transactivator proteins of herpes simplex virus

1994 • 51 citations

Mutational analysis of the sequence encoding ICP0 from herpes simplex virus type 1

1991 • 42 citations

Enhancement of RNA polymerase II initiation complexes by a novel DNA control domain downstream from the cap site of the cytomegalovirus major immediate-early promoter

1991 • 41 citations

Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor

1992 • 35 citations

Characterization of the mouse gene that encodes the delta/YY1/NF-E1/UCRBP transcription factor.

1993 • 35 citations

An autophosphorylating but not transphosphorylating activity is associated with the unique N terminus of the herpes simplex virus type 1 ribonucleotide reductase large subunit

1992 • 34 citations

Affinity purification of active subunit 1 of herpes simplex virus type 1 ribonucleotide reductase exhibiting a protein kinase activity

1991 • 32 citations

The intracisternal A-particle upstream element interacts with transcription factor YY1 to activate transcription: pleiotropic effects of YY1 on distinct DNA promoter elements.

1993 • 31 citations

Immediate-early gene regulation in herpes simplex virus

1993 • 25 citations

Identification of a large bent DNA domain and binding sites for serum response factor adjacent to the NFI repeat cluster and enhancer region in the major IE94 promoter from simian cytomegalovirus

1993 • 23 citations

YY1 is the cellular factor shown previously to bind to regulatory regions of several leaky-late (beta gamma, gamma 1) genes of herpes simplex virus type 1

1994 • 22 citations

Immediate early and functional AP-1 cis-response elements are involved in the transcriptional regulation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10)

1992 • 22 citations

Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors.

1992 • 21 citations

A herpes simplex virus type 1 mutant lacking the ICP0 introns reactivates with normal efficiency

1991 • 21 citations

Construction and characterization of herpes simplex type 1 viruses without introns in immediate early gene 1

1991 • 21 citations