Glucocorticoid Effects on NF-κB Binding in the Transcription of the ICAM-1 Gene

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

1995 • 2,386 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

1998 • 1,516 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

1998 • 1,200 citations

DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

1998 • 1,081 citations

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.

1994 • 1,057 citations

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.

1995 • 1,010 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Characterization of Mechanisms Involved in Transrepression of NF-κB by Activated Glucocorticoid Receptors

1995 • 815 citations

Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.

1995 • 487 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.

1995 • 438 citations

Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.

1994 • 423 citations

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

1997 • 371 citations

Endocrinology and Metabolism

1996 • 353 citations

Transcription factors 3: nuclear receptors.

1995 • 327 citations

Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.

1995 • 324 citations

Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.

1993 • 324 citations

Molecular mechanisms of anti‐inflammatory action of glucocorticoids

1996 • 313 citations

Nuclear Integration of Glucocorticoid Receptor and Nuclear Factor-κB Signaling by CREB-binding Protein and Steroid Receptor Coactivator-1

1998 • 307 citations

Ikappa Balpha -independent downregulation of NF-kappa B activity by glucocorticoid receptor

1997 • 298 citations

Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.

1992 • 282 citations

12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter.

1994 • 266 citations

Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B.

1996 • 228 citations

A Dual Mechanism Mediates Repression of NF-κB Activity by Glucocorticoids

1998 • 225 citations

Glucocorticoid-mediated Repression of NFκB Activity in Endothelial Cells Does Not Involve Induction of IκBα Synthesis

1996 • 204 citations

The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation.

1991 • 163 citations

Interaction of the COOH-terminal Transactivation Domain of p65 NF-κB with TATA-binding Protein, Transcription Factor IIB, and Coactivators

1995 • 157 citations

A New Function for the C-terminal Zinc Finger of the Glucocorticoid Receptor

1997 • 153 citations

Eukaryotic expression vectors for the analysis of mutant proteins

1989 • 126 citations

Glucocorticoid-mediated Gene Suppression of Rat Cytokine-induced Neutrophil Chemoattractant CINC/gro, a Member of the Interleukin-8 Family, through Impairment of NF-κB Activation

1996 • 111 citations

Involvement of TFIID and USA Components in Transcriptional Activation of the Human Immunodeficiency Virus Promoter by NF-κB and Sp1

1998 • 87 citations

Glucocorticoid-Dependent Transcriptional Repression of the Osteocalcin Gene by Competitive Binding at the TATA Box

1997 • 78 citations

Nuclear Hormone Receptors

2011 • 51 citations

Studies on the Mechanism of Glucocorticoid-Mediated Repression from a Negative Glucocorticoid Response Element from the Bovine Prolactin Gene

1997 • 42 citations

Tumour Necrosis Factor α Causes Retention of Activated Glucocorticoid Receptor within the Cytoplasm of A549 Cells

1996 • 33 citations