Steroid receptor heterodimerization demonstrated in vitro and in vivo.

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Determinants of target gene specificity for steroid/thyroid hormone receptors

1989 • 954 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

1994 • 527 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Mineralocorticoid and Glucocorticoid Receptor Activities Distinguished by Nonreceptor Factors at a Composite Response Element

1993 • 461 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

1993 • 369 citations

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

1993 • 335 citations

Heterodimerization between mineralocorticoid and glucocorticoid receptor: A new principle of glucocorticoid action in the CNS

1994 • 285 citations

The N-terminal DNA-binding ‘zinc finger’ of the oestrogen and glucocorticoid receptors determines target gene specificity.

1988 • 265 citations

Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression

1993 • 261 citations

Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids.

1991 • 225 citations

Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor.

1993 • 190 citations

Mineralocorticoid receptor-mediated changes in membrane properties of rat CA1 pyramidal neurons in vitro.

1990 • 176 citations

Roles of type I and II corticosteroid receptors in regulation of basal activity in the hypothalamo-pituitary-adrenal axis during the diurnal trough and the peak: evidence for a nonadditive effect of combined receptor occupation.

1994 • 172 citations

ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension

1990 • 164 citations

Androgen-specific gene activation via a consensus glucocorticoid response element is determined by interaction with nonreceptor factors.

1992 • 141 citations

Characterization of sua7 mutations defines a domain of TFIIB involved in transcription start site selection in yeast.

1994 • 136 citations

Reciprocal changes in plasma corticosterone and testosterone in stressed male rats maintained in a visible burrow system: evidence for a mediating role of testicular 11 beta-hydroxysteroid dehydrogenase.

1994 • 125 citations

Serotonergic control of androgen-induced dominance

1994 • 99 citations

Retinoid Receptors

1993 • 88 citations

Monoclonal antibody to the rat glucocorticoid receptor. Relationship between the immunoreactive and DNA-binding domain.

1985 • 88 citations

Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor.

1994 • 77 citations

Vertebrate receptors: molecular biology, dimerization and response elements

1994 • 59 citations

Molecular nephrology : kidney function in health and disease

1995 • 57 citations

Mechanism of synergistic transcriptional transactivation by the human glucocorticoid receptor.

1991 • 48 citations

A mechanistic basis for distinct mineralocorticoid and glucocorticoid receptor transcriptional specificities

1994 • 26 citations

Mutations That Alter Ligand-induced Switches and Dimerization Activities in the Retinoid X Receptor

1994 • 21 citations

Differential regulation of mouse mammary tumor virus-bacterial chloramphenicol acetyltranferase chimeric gene by human mineralocorticoid hormone-receptor complexes

1991 • 20 citations