Tumor Necrosis Factor/Tumor Necrosis Factor Receptor Family Members That Positively Regulate Immunity

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

2002 • 1,745 citations

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

2002 • 1,583 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

CD4+CD25+ Immunoregulatory T Cells

2002 • 1,434 citations

RANK is essential for osteoclast and lymph node development

1999 • 1,417 citations

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

2002 • 1,246 citations

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

2000 • 1,171 citations

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

2000 • 1,119 citations

Herpes Simplex Virus-1 Entry into Cells Mediated by a Novel Member of the TNF/NGF Receptor Family

1996 • 1,068 citations

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

2001 • 1,048 citations

BCMA Is Essential for the Survival of Long-lived Bone Marrow Plasma Cells

2004 • 1,014 citations

BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

2001 • 889 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

2003 • 848 citations

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

2002 • 816 citations

RANK-L and RANK: T Cells, Bone Loss, and Mammalian Evolution

2002 • 802 citations

Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases

2001 • 784 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

CD27 is required for generation and long-term maintenance of T cell immunity

2000 • 726 citations

Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus

2001 • 723 citations

TACI is mutant in common variable immunodeficiency and IgA deficiency

2005 • 691 citations

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

2002 • 679 citations

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans

2005 • 659 citations

OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

2001 • 638 citations

TACI-Ig Neutralizes Molecules Critical for B Cell Development and Autoimmune Disease

2001 • 611 citations

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

2004 • 595 citations

Synthesis and release of B-lymphocyte stimulator from myeloid cells

2001 • 576 citations

Reduced Competitiveness of Autoantigen-Engaged B Cells due to Increased Dependence on BAFF

2004 • 564 citations

The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome

2003 • 541 citations

TACI and BAFF-R mediate isotype switching in B cells

2005 • 523 citations

Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses

1998 • 515 citations

Regulation of the T-Independent Humoral Response by TACI

2001 • 513 citations

Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells

2004 • 498 citations

B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations

2003 • 480 citations

B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells

2004 • 479 citations

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

2005 • 474 citations

Expression and function of OX40 ligand on human dendritic cells.

1997 • 416 citations

Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival

1999 • 414 citations

Triggering of OX40 (CD134) on CD4+CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR

2005 • 406 citations

Loss of TACI Causes Fatal Lymphoproliferation and Autoimmunity, Establishing TACI as an Inhibitory BLyS Receptor

2003 • 400 citations

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

2001 • 399 citations

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1995 • 398 citations

The OX40 Costimulatory Receptor Determines the Development of CD4 Memory by Regulating Primary Clonal Expansion

2000 • 395 citations

LIGHT, a TNF-Like Molecule, Costimulates T Cell Proliferation and Is Required for Dendritic Cell-Mediated Allogeneic T Cell Response

2000 • 394 citations

Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

2000 • 393 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology

2004 • 365 citations

CD4 T Cell Cytokine Differentiation: The B Cell Activation Molecule, OX40 Ligand, Instructs CD4 T Cells to Express Interleukin 4 and Upregulates Expression of the Chemokine Receptor, Blr-1

1998 • 358 citations

Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

2004 • 358 citations

CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

2003 • 355 citations

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

2003 • 353 citations

Identification of proteoglycans as the APRIL-specific binding partners

2005 • 352 citations

4-1BB Ligand Induces Cell Division, Sustains Survival, and Enhances Effector Function of CD4 and CD8 T Cells with Similar Efficacy

2001 • 352 citations

Priming of naive T cells inside tumors leads to eradication of established tumors

2004 • 344 citations

The role of APRIL and BAFF in lymphocyte activation

2005 • 344 citations

Life And Death Decisions

2004 • 337 citations

Trance, a Tumor Necrosis Factor Family Member, Enhances the Longevity and Adjuvant Properties of Dendritic Cells in Vivo

2000 • 335 citations

Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

1993 • 328 citations

4-1BB-mediated immunotherapy of rheumatoid arthritis

2004 • 324 citations

TRANCE, a TNF Family Member, Is Differentially Expressed on T Cell Subsets and Induces Cytokine Production in Dendritic Cells

1999 • 323 citations

CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand

1998 • 321 citations

Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40

2004 • 320 citations

Ox40-Ligand Has a Critical Costimulatory Role in Dendritic Cell:T Cell Interactions

1999 • 320 citations

OX40-Deficient Mice Are Defective in Th Cell Proliferation but Are Competent in Generating B Cell and CTL Responses after Virus Infection

1999 • 320 citations

G-CSF–stimulated Neutrophils Are a Prominent Source of Functional BLyS

2003 • 317 citations

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

1996 • 316 citations

Macrophage- and dendritic cell—dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF

2003 • 311 citations

Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway

2000 • 309 citations

Cutting Edge: BLyS Enables Survival of Transitional and Mature B Cells Through Distinct Mediators

2002 • 309 citations

The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells.

1996 • 303 citations

A Newly Identified Member of the Tumor Necrosis Factor Receptor Superfamily with a Wide Tissue Distribution and Involvement in Lymphocyte Activation

1997 • 302 citations

Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene

2000 • 297 citations

CD30: expression and function in health and disease

1998 • 294 citations

Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease

2003 • 291 citations

Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells

2004 • 288 citations

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

2002 • 285 citations

Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.

1994 • 284 citations

Impairment of Antigen-Presenting Cell Function in Mice Lacking Expression of Ox40 Ligand

2000 • 284 citations

Analysis of 4-1BB Ligand (4-1BBL)-Deficient Mice and of Mice Lacking Both 4-1BBL and CD28 Reveals a Role for 4-1BBL in Skin Allograft Rejection and in the Cytotoxic T Cell Response to Influenza Virus

1999 • 280 citations

LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.

1998 • 277 citations

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

2005 • 276 citations

Compromised Ox40 Function in Cd28-Deficient Mice Is Linked with Failure to Develop Cxc Chemokine Receptor 5–Positive Cd4 Cells and Germinal Centers

1999 • 275 citations

Temporal Segregation of 4-1BB Versus CD28-Mediated Costimulation: 4-1BB Ligand Influences T Cell Numbers Late in the Primary Response and Regulates the Size of the T Cell Memory Response Following Influenza Infection

2002 • 270 citations

Cross-Talk between Activated Human NK Cells and CD4+ T Cells via OX40-OX40 Ligand Interactions

2004 • 262 citations

TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation

1999 • 262 citations

Normal B Cell Homeostasis Requires B Cell Activation Factor Production by Radiation-resistant Cells

2003 • 259 citations

4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

1999 • 259 citations

Targeted Disruption of LIGHT Causes Defects in Costimulatory T Cell Activation and Reveals Cooperation with Lymphotoxin β in Mesenteric Lymph Node Genesis

2002 • 255 citations

Blocking OX-40/OX-40 Ligand Interaction In Vitro and In Vivo Leads to Decreased T Cell Function and Amelioration of Experimental Allergic Encephalomyelitis

1999 • 250 citations

B Cell-Activating Factor Belonging to the TNF Family Acts through Separate Receptors to Support B Cell Survival and T Cell-Independent Antibody Formation

2004 • 249 citations

Tumor Necrosis Factor (TNF) Receptor Superfamily Member TACI Is a High Affinity Receptor for TNF Family Members APRIL and BLyS

2000 • 248 citations

OX40 Costimulation Enhances Interleukin-4 (IL-4) Expression at Priming and Promotes the Differentiation of Naive Human CD4+ T Cells Into High IL-4–Producing Effectors

1998 • 247 citations

EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching

2003 • 246 citations

OX40 (CD134) Controls Memory T Helper 2 Cells that Drive Lung Inflammation

2003 • 244 citations

Sustained Survivin Expression from OX40 Costimulatory Signals Drives T Cell Clonal Expansion

2005 • 243 citations

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

2005 • 241 citations

Constitutive Expression of LIGHT on T Cells Leads to Lymphocyte Activation, Inflammation, and Tissue Destruction

2001 • 240 citations

Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation.

1995 • 239 citations

Constitutive CD27/CD70 Interaction Induces Expansion of Effector-Type T Cells and Results in IFNγ-Mediated B Cell Depletion

2001 • 237 citations

Costimulation via OX40L Expressed by B Cells Is Sufficient to Determine the Extent of Primary CD4 Cell Expansion and Th2 Cytokine Secretion In Vivo

2003 • 235 citations

Critical Contribution of Ox40 Ligand to T Helper Cell Type 2 Differentiation in Experimental Leishmaniasis

2000 • 235 citations

Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions

2002 • 231 citations

Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells

2002 • 231 citations

CD4+CD3− Accessory Cells Costimulate Primed CD4 T Cells through OX40 and CD30 at Sites Where T Cells Collaborate with B Cells

2003 • 226 citations

T Cell Costimulation by the TNF Ligand BAFF

2001 • 225 citations

The regulation of T cell homeostasis and autoimmunity by T cell–derived LIGHT

2001 • 225 citations

4‐1BB T‐cell antigen binds to mature B cells and macrophages, and costimulates anti‐μ‐primed splenic B cells

1994 • 223 citations

Immune Responses in 4-1BB (CD137)-Deficient Mice

2002 • 221 citations

The regulation of T cell homeostasis and autoimmunity by T cell–derived LIGHT

2001 • 213 citations

Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines

2005 • 211 citations

CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism

2004 • 210 citations

The costimulation-regulated duration of PKB activation controls T cell longevity

2004 • 208 citations

TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice

2001 • 207 citations

Lymphotoxin and LIGHT signaling pathways and target genes

2004 • 207 citations

Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions.

1993 • 205 citations

CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells.

1993 • 204 citations

Development of Allergic Inflammation in a Murine Model of Asthma Is Dependent on the Costimulatory Receptor Ox40

2001 • 204 citations

Cutting Edge: The Natural Ligand for Glucocorticoid-Induced TNF Receptor-Related Protein Abrogates Regulatory T Cell Suppression

2004 • 202 citations

Expression of the Murine CD27 Ligand CD70 In Vitro and In Vivo

2003 • 193 citations

Administration of Agonistic Anti-4-1BB Monoclonal Antibody Leads to the Amelioration of Experimental Autoimmune Encephalomyelitis

2002 • 193 citations

Plasmacytoid Dendritic Cells Regulate Th Cell Responses through OX40 Ligand and Type I IFNs

2004 • 191 citations

Evidence that human CD8+CD45RA+CD27– cells are induced by antigen and evolve through extensive rounds of division

1999 • 190 citations

Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndrome

2004 • 186 citations

APRIL-Deficient Mice Have Normal Immune System Development

2004 • 186 citations

The role of herpesvirus entry mediator as a negative regulator of T cell–mediated responses

2005 • 185 citations

Reverse signaling via CD30 ligand.

1996 • 184 citations

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

2002 • 178 citations

Signaling Through NK Cell-Associated CD137 Promotes Both Helper Function for CD8+ Cytolytic T Cells and Responsiveness to IL-2 But Not Cytolytic Activity

2002 • 177 citations

Costimulation of CD8 T Cell Responses by OX40

2004 • 176 citations

Reciprocal Expression of the TNF Family Receptor Herpes Virus Entry Mediator and Its Ligand LIGHT on Activated T Cells: LIGHT Down-Regulates Its Own Receptor

2000 • 176 citations

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

2003 • 174 citations

Cutting Edge: BAFF Regulates CD21/35 and CD23 Expression Independent of Its B Cell Survival Function

2004 • 174 citations

Regulation of T Cell Activation In Vitro and In Vivo by Targeting the OX40-OX40 Ligand Interaction: Amelioration of Ongoing Inflammatory Bowel Disease with an OX40-IgG Fusion Protein, But Not with an OX40 Ligand-IgG Fusion Protein

1999 • 172 citations

Characterization of the human CD27 ligand, a novel member of the TNF gene family.

1994 • 171 citations

Frequencies of Circulating Cytolytic, CD45RA+CD27−, CD8+ T Lymphocytes Depend on Infection with CMV

2003 • 169 citations

Role of GITR in activation response of T lymphocytes

2002 • 169 citations

Role of CD4 T Cell Help and Costimulation in CD8 T Cell Responses During Listeria monocytogenes Infection

2003 • 168 citations

Robust B Cell Immunity but Impaired T Cell Proliferation in the Absence of CD134 (OX40)

1999 • 167 citations

Cutting Edge: Ligation of the Glucocorticoid-Induced TNF Receptor Enhances Autoreactive CD4+ T Cell Activation and Experimental Autoimmune Encephalomyelitis

2004 • 164 citations

Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases

2004 • 160 citations

Selective depletion of myelin–reactive T cells with the anti–OX–40 antibody ameliorates autoimmune encephalomyelitis

1996 • 159 citations

T Cell Proliferation by Direct Cross-Talk between OX40 Ligand on Human Mast Cells and OX40 on Human T Cells: Comparison of Gene Expression Profiles between Human Tonsillar and Lung-Cultured Mast Cells

2004 • 159 citations

Mice Deficient in OX40 and CD30 Signals Lack Memory Antibody Responses because of Deficient CD4 T Cell Memory

2005 • 158 citations

BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

2003 • 157 citations

BAFF production by antigen-presenting cells provides T cell co-stimulation

2004 • 156 citations

Human Tc1 and Tc2/Tc0 CD8 T-cell clones display distinct cell surface and functional phenotypes

2000 • 153 citations

4-1BB and OX40 Act Independently to Facilitate Robust CD8 and CD4 Recall Responses

2004 • 151 citations

Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis

2000 • 151 citations

Ligation of 4-1BB (CDw137) Regulates Graft-Versus-Host Disease, Graft-Versus-Leukemia, and Graft Rejection in Allogeneic Bone Marrow Transplant Recipients

2001 • 147 citations

Regulation of Murine Inflammatory Bowel Disease by CD25+ and CD25− CD4+ Glucocorticoid-Induced TNF Receptor Family-Related Gene+ Regulatory T Cells

2003 • 142 citations

Expression of the Costimulatory Receptor CD30 Is Regulated by Both CD28 and Cytokines

1998 • 140 citations

The cloning of CD70 and its identification as the ligand for CD27.

1994 • 139 citations

OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand

1996 • 138 citations

Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis

2000 • 138 citations

Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma.

1997 • 131 citations

BAFF binding to T cell‐expressed BAFF‐R costimulates T cell proliferation and alloresponses

2004 • 131 citations

A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo

2004 • 130 citations

Antibodies to TR2 (Herpesvirus Entry Mediator), a New Member of the TNF Receptor Superfamily, Block T Cell Proliferation, Expression of Activation Markers, and Production of Cytokines

1998 • 127 citations

Structure and expression of murine CD30 and its role in cytokine production.

1996 • 126 citations

LIGHT–HVEM signaling and the regulation of T cell-mediated immunity

2003 • 125 citations

Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand

2000 • 120 citations

Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue

2002 • 119 citations

CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity.

1994 • 119 citations

4-1BB (CD137) controls the clonal expansion and survival of CD8 T cellsin vivo but does not contribute to the development of cytotoxicity

2002 • 117 citations

CD30 Overexpression Enhances Negative Selection in the Thymus and Mediates Programmed Cell Death Via a Bcl-2-Sensitive Pathway

1999 • 109 citations

CD70+ antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa

2005 • 106 citations

Expression of CD27 on Murine Hematopoietic Stem and Progenitor Cells

2000 • 105 citations

CD30 Signals Integrate Expression of Cytotoxic Effector Molecules, Lymphocyte Trafficking Signals, and Signals for Proliferation and Apoptosis

2000 • 98 citations

T Cell Accumulation in B Cell Follicles Is Regulated by Dendritic Cells and Is Independent of B Cell Activation

2003 • 95 citations

Cutting Edge: Selective Impairment of CD8+ T Cell Function in Mice Lacking the TNF Superfamily Member LIGHT

2002 • 94 citations

Regulation of expression of CD27, a T cell-specific member of a novel family of membrane receptors.

1991 • 94 citations

In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway

2002 • 92 citations

The Critical Role of LIGHT in Promoting Intestinal Inflammation and Crohn’s Disease

2005 • 90 citations

CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes

2000 • 83 citations

CD137 is expressed by follicular dendritic cells and costimulates B lymphocyte activation in germinal centers

2002 • 83 citations

Regulation of murine B cell growth and differentiation by CD30 ligand

1995 • 83 citations

Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor

2005 • 83 citations

Characterization of murine CD70, the ligand of the TNF receptor family member CD27.

1997 • 81 citations

Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells.

1997 • 79 citations

CD30/CD30 Ligand (CD153) Interaction Regulates CD4+ T Cell-Mediated Graft-versus-Host Disease

2004 • 79 citations

The evolving crosstalk between co-stimulatory and co-inhibitory receptors: HVEM–BTLA

2005 • 77 citations

Phenotype and function of human B cells expressing CD70 (CD27 ligand)

1996 • 75 citations

Enhanced CD4 T Cell Responsiveness in the Absence of 4-1BB

2005 • 66 citations

Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells

2003 • 65 citations

A zinc metalloproteinase is responsible for the release of cd30 on human tumor cell lines

1995 • 64 citations

The Role of OX40 Ligand Interactions in the Development of the Th2 Response to the Gastrointestinal Nematode Parasite Heligmosomoides polygyrus

2003 • 63 citations

Cloning and expression of murine CD27: comparison with 4-1BB, another lymphocyte-specific member of the nerve growth factor receptor family

1993 • 62 citations

Antigen‐presenting cell‐derived signals determine expression levels of CD70 on‘qc primed T cells

1997 • 60 citations

Immune activation modulates hematopoiesis through interactions between CD27 and CD70

2005 • 60 citations

The role of herpesvirus entry mediator as a negative regulator of T cell–mediated responses

2005 • 58 citations

Extremely Rapid and Intense Induction of Apoptosis in Human Eosinophils by Anti-CD30 Antibody Treatment In Vitro

2004 • 57 citations

Impaired Recall of CD8 Memory T Cells in Immunologically Privileged Tissue

2005 • 56 citations

The role of CD30 in the pathogenesis of haematopoietic malignancies

2004 • 54 citations

The TNF Receptor Family Member CD30 Is Not Essential for Negative Selection

2000 • 50 citations

4-1BB (CD137) Is Required for Rapid Clearance ofListeria monocytogenesInfection

2005 • 48 citations

CD30—Governor of Memory T Cells?

2002 • 44 citations

Immune regulatory loops determine productive interactions within human T lymphocyte–dendritic cell clusters

1999 • 38 citations

Cell membrane-specific epitopes on CD30: Potentially superior targets for immunotherapy

2005 • 35 citations

Contribution of CD30/CD153 but not of CD27/CD70, CD134/OX40L, or CD137/4-1BBL to the optimal induction of protective immunity to Mycobacterium avium

2004 • 35 citations

Alternative molecular form of human T cell‐specific antigen CD27 expressed upon T cell activation

1989 • 34 citations

Subset-Specific Regulation of the Lymphatic Exit of Recirculating Lymphocytes In Vivo

2000 • 33 citations

Nitric Oxide Inhibits IFN-α Production of Human Plasmacytoid Dendritic Cells Partly via a Guanosine 3′,5′-Cyclic Monophosphate-Dependent Pathway

2005 • 30 citations

Characterization and functional study of five novel monoclonal antibodies against human OX40L highlight reverse signalling: enhancement of IgG production of B cells and promotion of maturation of DCs

2004 • 23 citations

Essential Role of OX40L on B Cells in Persistent Alloantibody Production Following Repeated Alloimmunizations

2004 • 18 citations