Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

1998 • 2,658 citations

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

2002 • 1,745 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

1998 • 1,579 citations

CD4+CD25+ Immunoregulatory T Cells

2002 • 1,434 citations

Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance

1999 • 1,223 citations

Direct Expansion of Functional CD25+ CD4+ Regulatory T Cells by Antigen-processing Dendritic Cells

2003 • 893 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Direct effects of IL-10 on subsets of human CD4+ T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation.

1993 • 628 citations

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

1995 • 489 citations

Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas

1995 • 462 citations

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

1997 • 410 citations

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

2003 • 353 citations

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

1992 • 342 citations

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

1998 • 342 citations

Tumor necrosis factor receptor superfamily members and their ligands

1994 • 313 citations

Role of 4-1BB in immune responses

1998 • 312 citations

Naturally anergic and suppressive CD25+CD4+ T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation

2000 • 294 citations

Human interleukin-10 can directly inhibit T-cell growth

1993 • 283 citations

CD27, a Member of the Tumor Necrosis Factor Receptor Superfamily, Activates NF-κB and Stress-activated Protein Kinase/c-Jun N-terminal Kinase via TRAF2, TRAF5, and NF-κB-inducing Kinase

1998 • 239 citations

CD4+ CD25+ Regulatory T Cells Control T Helper Cell Type 1 Responses to Foreign Antigens Induced by Mature Dendritic Cells In Vivo

2003 • 230 citations

Signaling by the TNF Receptor Superfamily and T Cell Homeostasis

2000 • 194 citations

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

1999 • 191 citations

Identification of a Novel Activation-inducible Protein of the Tumor Necrosis Factor Receptor Superfamily and Its Ligand

1999 • 188 citations

CD28-Independent Costimulation of T Cells by OX40 Ligand and CD70 on Activated B Cells

1999 • 180 citations

Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.

1995 • 178 citations

Role of GITR in activation response of T lymphocytes

2002 • 169 citations

Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule

1995 • 156 citations

Human interleukin-10 can directly inhibit T-cell growth

1993 • 143 citations

Interleukin‐10 rescues T cells from apoptotic cell death: association with an upregulation of Bcl‐2

1997 • 141 citations

CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation.

1994 • 120 citations

T cell life and death signalling via TNF-receptor family members

2000 • 111 citations

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

2002 • 98 citations

The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity

1996 • 88 citations

Functions of newly identified members of the tumor necrosis factor receptor/ligand superfamilies in lymphocytes

1999 • 67 citations

Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells

2003 • 65 citations

Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56lck1.

1993 • 62 citations

Molecular Mechanisms Underlying Differential Contribution of CD28 Versus Non-CD28 Costimulatory Molecules to IL-2 Promoter Activation

2002 • 54 citations

CD28-mediated costimulation is necessary for the activation of T cell receptor-gamma delta+ T lymphocytes.

1993 • 52 citations

Blockade of CTLA-4 Signals Inhibits Th2-Mediated Murine Chronic Graft-Versus-Host Disease by an Enhanced Expansion of Regulatory CD8+ T Cells

2000 • 44 citations

The Role of CD28 Costimulation in the Generation of Cytotoxic T Lymphocytes

1995 • 23 citations

Rapid induction of CD95 ligand and CD4+ T cell-mediated apoptosis by CD137 (4–1BB) costimulation

2001 • 12 citations