Costimulation via OX40L Expressed by B Cells Is Sufficient to Determine the Extent of Primary CD4 Cell Expansion and Th2 Cytokine Secretion In Vivo

The B7–CD28 superfamily

2002 • 1,646 citations

Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements

1998 • 1,460 citations

Dendritic cell regulation of TH1-TH2 development

2000 • 1,136 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

Reciprocal regulation of polarized cytokine production by effector B and T cells

2000 • 817 citations

Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node

1998 • 762 citations

ICOS is essential for effective T-helper-cell responses

2001 • 666 citations

OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

2001 • 638 citations

Signaling and Transcription in T Helper Development

2000 • 635 citations

Effect of interleukin‐10 on dendritic cell maturation and function

1997 • 571 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

2002 • 517 citations

The Role of CD40 Ligand in Costimulation and T‐Cell Activation

1996 • 441 citations

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1995 • 398 citations

Cytokine-induced survival of activated T cellsin vitroandin vivo

1998 • 395 citations

The OX40 Costimulatory Receptor Determines the Development of CD4 Memory by Regulating Primary Clonal Expansion

2000 • 395 citations

CD4 T Cell Cytokine Differentiation: The B Cell Activation Molecule, OX40 Ligand, Instructs CD4 T Cells to Express Interleukin 4 and Upregulates Expression of the Chemokine Receptor, Blr-1

1998 • 358 citations

Ox40-Ligand Has a Critical Costimulatory Role in Dendritic Cell:T Cell Interactions

1999 • 320 citations

T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes.

1987 • 286 citations

Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.

1994 • 284 citations

Impairment of Antigen-Presenting Cell Function in Mice Lacking Expression of Ox40 Ligand

2000 • 284 citations

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response.

1996 • 284 citations

Antigen decoding by T lymphocytes: from synapses to fate determination

2001 • 261 citations

Splenic T Zone Development Is B Cell Dependent

2001 • 245 citations

Critical Contribution of Ox40 Ligand to T Helper Cell Type 2 Differentiation in Experimental Leishmaniasis

2000 • 235 citations

A Critical Role for B Cells in the Development of Memory CD4 Cells

2000 • 225 citations

Production of cytokines by human B cells in health and disease

1997 • 221 citations

Growth Factor Independent-1 Induced by IL-4 Regulates Th2 Cell Proliferation

2002 • 207 citations

Instruction for Cytokine Expression in T Helper Lymphocytes in Relation to Proliferation and Cell Cycle Progression

1999 • 190 citations

CD4 T cell traffic control:in vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles

1999 • 190 citations

The interplay between the duration of TCR and cytokine signaling determines T cell polarization

1999 • 187 citations

Robust B Cell Immunity but Impaired T Cell Proliferation in the Absence of CD134 (OX40)

1999 • 167 citations

Two Distinct Stages in the Transition from Naive CD4 T Cells to Effectors, Early Antigen-Dependent and Late Cytokine-Driven Expansion and Differentiation

2000 • 161 citations

Role of Ox40 Signals in Coordinating Cd4 T Cell Selection, Migration, and Cytokine Differentiation in T Helper (Th)1 and Th2 Cells

2000 • 143 citations

Conventional, Naive CD4+ T Cells Provide an Initial Source of IL-4 During Th2 Differentiation

2000 • 122 citations

Antigen-specific B cells preferentially induce CD4+ T cells to produce IL-4.

1997 • 117 citations

Abortive Proliferation of Rare T Cells Induced by Direct or Indirect Antigen Presentation by Rare B Cells In Vivo

1998 • 88 citations

Frequencies of Neuroantigen-Specific T Cells in the Central Nervous System Versus the Immune Periphery During the Course of Experimental Allergic Encephalomyelitis

2001 • 80 citations

Germinal Center B Cells Constitute a Predominant Physiological Source of IL-4: Implication for Th2 Development In Vivo

2002 • 58 citations

Availability of antigen-presenting cells can determine the extent of CD4 effector expansion and priming for secretion of Th2 cytokines in vivo

2002 • 35 citations