Phenotype and function of human B cells expressing CD70 (CD27 ligand)

Germinal Centers

1994 • 1,680 citations

Leukocyte Typing II

1986 • 688 citations

Analysis of somatic mutation in five B cell subsets of human tonsil.

1994 • 667 citations

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

1995 • 425 citations

Fas ligation induces apoptosis of CD40-activated human B lymphocytes.

1995 • 402 citations

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1995 • 398 citations

Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help).

1992 • 357 citations

CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair

1996 • 326 citations

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway.

1995 • 285 citations

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response.

1996 • 284 citations

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

1993 • 280 citations

CD40 preferentially costimulates activation of CD4+ T lymphocytes.

1994 • 255 citations

Immunological Memory

1993 • 250 citations

The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.

1991 • 245 citations

Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation.

1995 • 239 citations

Characterization of the human CD27 ligand, a novel member of the TNF gene family.

1994 • 171 citations

Cytokine expression by germinal center cells.

1993 • 161 citations

IgM and IgG but not cytokine secretion is restricted to the CD27+ B lymphocyte subset.

1992 • 142 citations

CD27 expression by a distinct subpopulation of human B lymphocytes

1990 • 138 citations

Expression and release of CD27 in human B-cell malignancies

1993 • 130 citations

Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.

1995 • 127 citations

CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation.

1994 • 120 citations

CD70 represents the human ligand for CD27

1994 • 113 citations

CD27/CD70 interaction directly drives B cell IgG and IgM synthesis

1995 • 88 citations

A dual role for both CD40-ligand and TNF-alpha in controlling human B cell death.

1996 • 80 citations

Differentiation of the Secondary B‐Lymphocyte Repertoire: The Germinal Center Reaction

1994 • 68 citations

Immobilized anti-CD3 monoclonal antibodies induce accessory cell-independent lymphokine production, proliferation and helper activity in human T lymphocytes.

1989 • 63 citations

Role of CD27 in T cell immune response. Analysis by recombinant soluble CD27.

1994 • 62 citations

Functional characterization of a novel anti‐B7 monoclonal antibody

1992 • 56 citations

CD27-CD27 ligand/CD70 interactions enhance alloantigen-induced proliferation and cytolytic activity in CD8+ T lymphocytes.

1995 • 54 citations

Identification of a novel subpopulation of germinal center B cells characterized by expression of IgD and CD70

1996 • 43 citations

Anti‐CD27 monoclonal antibodies identify two functionally distinct subpopulations within the CD4⁺ T cell subset

1988 • 28 citations

Regulation of T-cell differentiation by CD2 and CD28 accessory molecules.

1991 • 23 citations