4-1BB-mediated immunotherapy of rheumatoid arthritis

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

1998 • 2,538 citations

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1997 • 1,651 citations

Analysis of Messy Data

1992 • 1,517 citations

Modulation of tryptophan catabolism by regulatory T cells

2003 • 1,323 citations

CTLA-4–Ig regulates tryptophan catabolism in vivo

2002 • 1,150 citations

Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

1998 • 956 citations

Analysis of Messy Data, Volume I: Designed Experiments

1985 • 931 citations

Inhibition of Allogeneic T Cell Proliferation by Indoleamine 2,3-Dioxygenase–expressing Dendritic Cells

2002 • 917 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 • 777 citations

Cutting Edge: Induced Indoleamine 2,3 Dioxygenase Expression in Dendritic Cell Subsets Suppresses T Cell Clonal Expansion

2003 • 460 citations

Inducible T cell antigen 4-1BB. Analysis of expression and function.

1993 • 416 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

The Efficiency of Simulation-Based Multiple Comparisons

1987 • 303 citations

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

2002 • 285 citations

Temporal Segregation of 4-1BB Versus CD28-Mediated Costimulation: 4-1BB Ligand Influences T Cell Numbers Late in the Primary Response and Regulates the Size of the T Cell Memory Response Following Influenza Infection

2002 • 270 citations

Tryptophan Catabolism and Regulation of Adaptive Immunity

2003 • 198 citations

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses

2002 • 195 citations

Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.

1994 • 188 citations

Anti–4-1bb Monoclonal Antibodies Abrogate T Cell–Dependent Humoral Immune Responses in Vivo through the Induction of Helper T Cell Anergy

1999 • 184 citations

The molecular pathogenesis of collagen-induced arthritis in mice—a model for rheumatoid arthritis

2002 • 181 citations

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

2002 • 178 citations

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

2003 • 174 citations

Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB

2002 • 162 citations

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

2003 • 152 citations

Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process

2000 • 121 citations

The effect of treatment with interferon-gamma on type II collagen-induced arthritis

1990 • 93 citations

The pathophysiology and treatment of rheumatoid arthritis

1997 • 76 citations

Analysis of Messy Data, Volume I: Designed Experiments.

1986 • 75 citations

Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering

2003 • 71 citations

Pathogenesis of the joint disease of rheumatoid arthritis

1983 • 33 citations