Expression of the Costimulatory Receptor CD30 Is Regulated by Both CD28 and Cytokines

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1993 • 877 citations

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 • 777 citations

Evidence for a differential avidity model of T cell selection in the thymus

1994 • 679 citations

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.

1989 • 662 citations

IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

1996 • 653 citations

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

1993 • 541 citations

New perspectives of C1328-137-mediated T cell costimulation

1995 • 526 citations

Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region

1996 • 484 citations

Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas

1995 • 462 citations

Transducers of life and death: TNF receptor superfamily and associated proteins.

1996 • 423 citations

Expansion or Elimination of B Cells In Vivo: Dual Roles for CD40- and Fas (CD95)-Ligands Modulated by the B Cell Antigen Receptor

1996 • 405 citations

Absence of B7-dependent responses in CD28-deficient mice

1994 • 386 citations

Preferential expression of CD30 by human CD4 ⁺ T cells producing Th2‐type cytokines

1995 • 368 citations

Costimulation of CD28- T lymphocytes by 4-1BB ligand.

1997 • 333 citations

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

1996 • 316 citations

Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines

1994 • 303 citations

Interleukin 13 is a B cell stimulating factor.

1994 • 298 citations

Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor.

1993 • 297 citations

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway.

1995 • 285 citations

CD28 costimulation prevents cell death during primary T cell activation.

1996 • 270 citations

Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death.

1997 • 256 citations

Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response.

1995 • 220 citations

Induction of Nuclear Factor κB by the CD30 Receptor Is Mediated by TRAF1 and TRAF2

1997 • 214 citations

CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.

1994 • 210 citations

CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells.

1993 • 204 citations

CD40-mediated signaling in B cells. Balancing cell survival, growth, and death.

1996 • 186 citations

CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificity.

1996 • 173 citations

CD30 Contains Two Binding Sites with Different Specificities for Members of the Tumor Necrosis Factor Receptor-associated Factor Family of Signal Transducing Proteins

1996 • 171 citations

T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.

1996 • 165 citations

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

1995 • 163 citations

An essential role for gp39, the ligand for CD40, in thymic selection.

1995 • 148 citations

CD30 and type 2 T helper (Th2) responses

1995 • 139 citations

Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma.

1997 • 131 citations

Structure and expression of murine CD30 and its role in cytokine production.

1996 • 126 citations

CD28 activation promotes Th2 subset differentiation by human CD4⁺ cells

1995 • 122 citations

CD30 expression does not discriminate between human Th1- and Th2-type T cells.

1996 • 120 citations

Similarities and differences in signal transduction by interleukin 4 and interleukin 13: analysis of Janus kinase activation.

1995 • 118 citations

Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction.

1995 • 114 citations

CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4.

1993 • 112 citations

Limited role of CD28-mediated signals in T helper subset differentiation.

1996 • 111 citations

CD40 signaling-mediated induction of Bcl-XL, Cdk4, and Cdk6. Implication of their cooperation in selective B cell growth.

1995 • 101 citations

Tumor necrosis factor receptor-associated factor (TRAF)-1, TRAF-2, and TRAF-3 interactin vivowith the CD30 cytoplasmic domain; TRAF-2 mediates CD30-induced nuclear factor kappa B activation

1996 • 78 citations

Recombinant CD30 ligand and CD40 ligand share common biological activities on Hodgkin and Reed‐Sternberg cells

1995 • 71 citations

Functional effects of CD30 on a large granular lymphoma cell line, YT. Inhibition of cytotoxicity, regulation of CD28 and IL-2R, and induction of homotypic aggregation.

1993 • 67 citations

Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-γ and interleukin-4 receptor-α

1996 • 59 citations

CD30 induction of human immunodeficiency virus gene transcription is mediated by TRAF2

1997 • 30 citations

Induction of competence to respond to IL-4 by CD4+ T helper type 1 cells requires costimulation.

1992 • 18 citations