4-1BB (CD137) Is Required for Rapid Clearance ofListeria monocytogenesInfection

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1997 • 1,444 citations

Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

1998 • 1,443 citations

CELLULAR RESISTANCE TO INFECTION

1962 • 1,422 citations

Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

1998 • 1,249 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

Role of hemolysin for the intracellular growth of Listeria monocytogenes.

1988 • 881 citations

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

2003 • 848 citations

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 • 777 citations

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

2002 • 753 citations

Phagocytosis and innate immunity

2002 • 579 citations

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

1996 • 534 citations

Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response

1992 • 459 citations

Discrete Generation of Superoxide and Hydrogen Peroxide by T Cell Receptor Stimulation

2002 • 447 citations

Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen

1993 • 426 citations

NK1.1 Cells Express 4-1BB (CDw137) Costimulatory Molecule and Are Required for Tumor Immunity Elicited by Anti-4-1BB Monoclonal Antibodies

1998 • 361 citations

4-1BB Promotes the Survival of CD8+ T Lymphocytes by Increasing Expression of Bcl-xL and Bfl-1

2002 • 358 citations

4-1BB Ligand Induces Cell Division, Sustains Survival, and Enhances Effector Function of CD4 and CD8 T Cells with Similar Efficacy

2001 • 352 citations

Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody.

1994 • 352 citations

Early gamma interferon production by natural killer cells is important in defense against murine listeriosis

1991 • 316 citations

Role of 4-1BB in immune responses

1998 • 312 citations

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

2002 • 285 citations

Temporal Segregation of 4-1BB Versus CD28-Mediated Costimulation: 4-1BB Ligand Influences T Cell Numbers Late in the Primary Response and Regulates the Size of the T Cell Memory Response Following Influenza Infection

2002 • 270 citations

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

2002 • 265 citations

Generation and Function of Reactive Oxygen Species in Dendritic Cells During Antigen Presentation

2003 • 246 citations

Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection.

1994 • 242 citations

Immune Responses in 4-1BB (CD137)-Deficient Mice

2002 • 221 citations

Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils.

1996 • 216 citations

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

2002 • 215 citations

Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils

1996 • 210 citations

Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium.

1991 • 200 citations

Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB

2002 • 162 citations

A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo

2004 • 130 citations

Induction of IFN-γ-producing CD4+ natural killer T cells byMycobacterium bovis bacillus Calmette Guérin

1999 • 126 citations

Analysis and assessment of the capacity of neutrophils to produce reactive oxygen species in a 96-well microplate format using lucigenin- and luminol-dependent chemiluminescence

1997 • 108 citations

Pillars article: cellular resistance to infection. J. Exp. Med. 1962. 116: 381-406.

2014 • 108 citations

The crucial role of polymorphonuclear leukocytes in resistance toSalmonella dublininfections in genetically susceptible and resistant mice

1998 • 102 citations

NK and CD8⁺ T cell‐mediated eradication of poorly immunogenic B16‐F10 melanoma by the combined action of IL‐12 gene therapy and 4‐1BB costimulation

2004 • 95 citations

Divergent effects of 4-1BB antibodies on antitumor immunity and on tumor-reactive T-cell generation.

2001 • 92 citations

IL-4 producing CD4⁺ TCRα β^int liver lymphocytes: influence of thymus, β₂-microglobulin and NK1.1 expression

1995 • 92 citations

CD137 activation abrogates granulocyte-macrophage colony-stimulating factor-mediated anti-apoptosis in neutrophils

2000 • 80 citations

Neutrophil–Kupffer-cell interaction in host defenses to systemic infections

1998 • 69 citations

Signal transduction mechanisms of C1q-mediated superoxide production. Evidence for the involvement of temporally distinct staurosporine-insensitive and sensitive pathways.

1992 • 67 citations

New insights into the role of 4-1BB in immune responses: beyond CD8+ T cells

2002 • 63 citations

Trp-Lys-Tyr-Met-Val-D-Met stimulates superoxide generation and killing of Staphylococcus aureus via phospholipase D activation in human monocytes

1999 • 55 citations

Immunity to <i>Listeria monocytogenes</i>

1998 • 43 citations

Why Listeriosis? A perspective on cellular immunity to infection

1997 • 36 citations

4-1BB (CD137) Differentially Regulates Murine In Vivo Protein- and Polysaccharide-Specific Immunoglobulin Isotype Responses toStreptococcus pneumoniae

2002 • 21 citations