Dendritic Cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

1994 • 5,605 citations

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

1997 • 5,058 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1998 • 4,184 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas

1995 • 2,833 citations

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 • 2,437 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1973 • 2,286 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

1998 • 2,078 citations

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Interleukin-10

1993 • 1,820 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Germinal Centers

1994 • 1,680 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

1997 • 1,608 citations

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1998 • 1,595 citations

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

1995 • 1,560 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

1998 • 1,448 citations

Origin, maturation and antigen presenting function of dendritic cells

1997 • 1,375 citations

Bone Marrow Transplant

2016 • 1,367 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Induction of tolerance by IL-10-treated dendritic cells.

1997 • 1,263 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

The Enigmatic Plasmacytoid T Cells Develop into Dendritic Cells with Interleukin (IL)-3 and CD40-Ligand

1997 • 1,224 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Pro‐inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum‐free conditions

1997 • 1,179 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

1997 • 1,143 citations

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.

1985 • 1,141 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Mechanism of antigen-driven selection in germinal centres

1989 • 1,097 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

1980 • 983 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.

1996 • 962 citations

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1995 • 959 citations

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

1997 • 937 citations

Cytomegalovirus Infection Is Associated With Cardiac Allograft Rejection and Atherosclerosis

1989 • 934 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Epidermal Langerhans cells are derived from cells originating in bone marrow

1979 • 879 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Host factors and the pathogenesis of HIV-induced disease

1996 • 857 citations

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

1996 • 849 citations

KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

1996 • 816 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance

1993 • 795 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice.

1978 • 791 citations

CAPTURE AND PROCESSING OF EXOGENOUS ANTIGENS FOR PRESENTATION ON MHC MOLECULES

1997 • 779 citations

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

1995 • 756 citations

Developmental regulation of MHC class II transport in mouse dendritic cells

1997 • 754 citations

Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.

1996 • 746 citations

c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities

1998 • 722 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood

1996 • 696 citations

Reactivation of Latent Human Cytomegalovirus by Allogeneic Stimulation of Blood Cells from Healthy Donors

1997 • 690 citations

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

1995 • 687 citations

Human CD14 mediates recognition and phagocytosis of apoptotic cells

1998 • 685 citations

Ueber die Nerven der menschlichen Haut

1868 • 678 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ.

1990 • 670 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells

1998 • 649 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1992 • 641 citations

Constitutive class I-restricted exogenous presentation of self antigens in vivo.

1996 • 637 citations

Dendritic Cells Exposed to Human Immunodeficiency Virus Type-1 Transmit a Vigorous Cytopathic Infection to CD4 ⁺ T Cells

1992 • 624 citations

A Requirement for Two Cell Types for Antibody Formation in vitro

1967 • 612 citations

Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells

1997 • 596 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain.

1981 • 589 citations

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

1995 • 577 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Dendritic cells in the T‐cell areas of lymphoid organs

1997 • 572 citations

Effect of interleukin‐10 on dendritic cell maturation and function

1997 • 571 citations

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells.

1988 • 565 citations

Mechanism of Suppression of Cell-Mediated Immunity by Measles Virus

1996 • 564 citations

Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

1990 • 561 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

1991 • 554 citations

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells.

1989 • 542 citations

Epidermal Langerhans cells bear Fc and C3 receptors

1977 • 541 citations

A dendritic-cell-derived C–C chemokine that preferentially attracts naive T cells

1997 • 532 citations

Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance.

1993 • 526 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

1996 • 523 citations

Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity

1998 • 518 citations

Antigen-bearing Langerhans cells in skin, dermal lymphatics and in lymph nodes

1976 • 510 citations

Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells

1998 • 509 citations

Transforming Growth Factor β1, in the Presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, Induces Differentiation of Human Peripheral Blood Monocytes into Dendritic Langerhans Cells

1998 • 507 citations

A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody

1979 • 506 citations

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1998 • 505 citations

Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1

1994 • 505 citations

ANTIGENS IN IMMUNITY

1968 • 497 citations

Kaposi's Sarcoma-Associated Herpesvirus Infection of Bone Marrow Dendritic Cells from Multiple Myeloma Patients

1997 • 491 citations

Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo.

1993 • 487 citations

Cutting Edge: Differential Regulation of Chemokine Receptors During Dendritic Cell Maturation: A Model for Their Trafficking Properties

1998 • 486 citations

Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin

1993 • 483 citations

Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin

1997 • 482 citations

Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B Cells

1998 • 479 citations

Phagocytosis of antigens by Langerhans cells in vitro.

1993 • 474 citations

Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1.

1995 • 472 citations

Targeted Expression of Major Histocompatibility Complex (MHC) Class II Molecules Demonstrates that Dendritic Cells Can Induce Negative but Not Positive Selection of Thymocytes In Vivo

1997 • 459 citations

Murine liver allograft transplantation: Tolerance and donor cell chimerism

1994 • 459 citations

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

1997 • 455 citations

Dendritic Cells Interact Directly with Naive B Lymphocytes to Transfer Antigen and Initiate Class Switching in a Primary T-Dependent Response

1998 • 454 citations

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells.

1990 • 453 citations

Interactions of tumor necrosis factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34+ progenitors in human bone marrow.

1992 • 452 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

CD34+ Hematopoietic Progenitors From Human Cord Blood Differentiate Along Two Independent Dendritic Cell Pathways in Response to Granulocyte-Macrophage Colony-Stimulating Factor Plus Tumor Necrosis Factor α: II. Functional Analysis

1997 • 442 citations

Measles Virus Suppresses Cell-mediated Immunity by Interfering with the Survival and Functions of Dendritic and T Cells

1997 • 431 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin.

1993 • 427 citations

A Novel Inhibitory Receptor (ILT3) Expressed on Monocytes, Macrophages, and Dendritic Cells Involved in Antigen Processing

1997 • 426 citations

Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes.

1996 • 424 citations

Expression and function of OX40 ligand on human dendritic cells.

1997 • 416 citations

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny.

1996 • 405 citations

Fas ligation induces apoptosis of CD40-activated human B lymphocytes.

1995 • 402 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells

1997 • 402 citations

A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

1998 • 402 citations

Phase I clinical trial: T-cell therapy for prostate cancer using autologous dendritic cells pulsed with HLA-A0201-specific peptides from prostate-specific membrane antigen

1996 • 398 citations

Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection

1997 • 398 citations

The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

1997 • 397 citations

Restoration of HIV-Specific Cell-Mediated Immune Responses by Interleukin-12 in Vitro

1993 • 397 citations

Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces.

1994 • 395 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity

1997 • 390 citations

Dendritic Cells Are Required for the Development of Chronic Eosinophilic Airway Inflammation in Response to Inhaled Antigen in Sensitized Mice

1998 • 389 citations

Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI.

1992 • 388 citations

Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma

1997 • 384 citations

Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules.

1994 • 383 citations

Receptor sites for Ca2+ channel antagonists

1992 • 382 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Developmental Regulation of Invariant Chain Proteolysis Controls MHC Class II Trafficking in Mouse Dendritic Cells

1998 • 378 citations

Systemic chimerism in human female recipients of male livers

1992 • 378 citations

COSTIMULATORY MOLECULE-DEFICIENT DENDRITIC CELL PROGENITORS (MHC CLASS II+, CD80dim, CD86-) PROLONG CARDIAC ALLOGRAFT SURVIVAL IN NONIMMUNOSUPPRESSED RECIPIENTS12

1996 • 378 citations

Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes.

1995 • 372 citations

Human cytomegalovirus latent infection of granulocyte-macrophage progenitors.

1994 • 362 citations

CCR6, a CC Chemokine Receptor that Interacts with Macrophage Inflammatory Protein 3α and Is Highly Expressed in Human Dendritic Cells

1997 • 362 citations

Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch.

1996 • 360 citations

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1997 • 357 citations

Differentiation of human dendritic cells from monocytes in vitro

1997 • 356 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 354 citations

Mechanisms of antigen uptake for presentation

1996 • 354 citations

Constitutive macropinocytosis allows TAP‐dependent major histocompatibility compex class I presentation of exogenous soluble antigen by bone marrow‐derived dendritic cells

1997 • 351 citations

Follicular Dendritic Cells as Accessory Cells

1990 • 351 citations

Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha.

1995 • 350 citations

B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.

1994 • 347 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

1993 • 347 citations

Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release.

1984 • 346 citations

Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back.

1997 • 342 citations

Langerhans cells require signals from both tumour necrosis factor‐α and interleukin‐1β for migration

1997 • 340 citations

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

1991 • 336 citations

A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.

1992 • 332 citations

Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.

1996 • 332 citations

Dendritic Cells Are Recruited into the Airway Epithelium during the Inflammatory Response to a Broad Spectrum of Stimuli

1996 • 331 citations

Interleukin‐12 profoundly up‐regulates the synthesis of antigen‐specific complement‐fixing IgG2a, IgG2b and IgG3 antibody subclasses in vivo

1995 • 331 citations

Expanding Dendritic Cells In Vivo Enhances the Induction of Oral Tolerance

1998 • 327 citations

CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair

1996 • 326 citations

Immature Dendritic Cells Selectively Replicate Macrophagetropic (M-Tropic) Human Immunodeficiency Virus Type 1, while Mature Cells Efficiently Transmit both M- and T-Tropic Virus to T Cells

1998 • 325 citations

Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells.

1995 • 324 citations

Modulation of osteoclast differentiation by local factors

1995 • 322 citations

Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid

1996 • 320 citations

CD4+ T Cell Help Impairs CD8+ T Cell Deletion Induced by Cross-presentation of Self-Antigens and Favors Autoimmunity

1997 • 320 citations

The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus

1989 • 318 citations

Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.

1995 • 318 citations

Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways.

1991 • 316 citations

Flt3 ligand induces tumor regression and antitumor immune responses in vivo

1997 • 315 citations

Life and Death in Germinal Centers (Redux)

1996 • 315 citations

Follicular dendritic cells and human immunodeficiency virus infectivity

1995 • 313 citations

Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

1997 • 311 citations

Dendritic cells capable of stimulating T cells in germinal centres

1996 • 309 citations

Dendritic Cells Retrovirally Transduced with a Model Antigen Gene Are Therapeutically Effective against Established Pulmonary Metastases

1997 • 309 citations

Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations.

1992 • 306 citations

Interleukin-10

1992 • 303 citations

Dendritic Cells Enhance Growth and Differentiation of CD40-activated B Lymphocytes

1997 • 301 citations

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo

1994 • 300 citations

Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication.

1983 • 300 citations

Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines.

1994 • 299 citations

Identification of dendritic cell colony-forming units among normal human CD34+ bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.

1995 • 296 citations

B Lymphocytes Induce the Formation of Follicular Dendritic Cell Clusters in a Lymphotoxin α–dependent Fashion

1998 • 296 citations

Adhesion of Human B Cells to Germinal Centers in Vitro Involves VLA-4 and INCAM-110

1990 • 295 citations

TECK: A Novel CC Chemokine Specifically Expressed by Thymic Dendritic Cells and Potentially Involved in T Cell Development

1997 • 292 citations

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes

1997 • 292 citations

Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen 1/intercellular adhesion molecule 1 and very late antigen 4/vascular cell adhesion molecule 1 pathways.

1991 • 291 citations

Major histocompatibility complex class I‐restricted CD8⁺ T cells and class II‐restricted CD4⁺ T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene

1995 • 291 citations

Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

1996 • 290 citations

Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells

1997 • 289 citations

Does T-cell tolerance require a dedicated antigen-presenting cell?

1989 • 288 citations

Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals.

1996 • 287 citations

Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo.

1993 • 284 citations

FOLLICULAR DENDRITIC CELLS AND VIRUS-LIKE PARTICLES IN AIDS-RELATED LYMPHADENOPATHY

1984 • 283 citations

Interleukin‐10 differentially regulates B7‐1 (CD80) and B7‐2 (CD86) expression on human peripheral blood dendritic cells

1995 • 282 citations

Human and murine dermis contain dendritic cells. Isolation by means of a novel method and phenotypical and functional characterization.

1993 • 279 citations

Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen‐specific T cells

1993 • 276 citations

Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.

1994 • 276 citations

Measles Virus Infects Human Dendritic Cells and Blocks Their Allostimulatory Properties for CD4+ T Cells

1997 • 274 citations

The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

1992 • 273 citations

Dendritic cells, but not macrophages, produce IL-12 immediately followingLeishmania donovani infection

1998 • 271 citations

CD44 splice variants: metastases meet lymphocytes

1993 • 268 citations

Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor

1996 • 265 citations

The selective engulfment of apoptotic bodies by dendritic cells is mediated by the αvβ3 integrin and requires intracellular and extracellular calcium

1997 • 262 citations

Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells

1998 • 262 citations

A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph.

1996 • 261 citations

The lost chord: microchimerism and allograft survival

1996 • 259 citations

Generation of human dendritic cells/Langerhans cells from circulating CD34+ hematopoietic progenitor cells

1996 • 259 citations

TNF in combination with GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages

1992 • 257 citations

Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice

1997 • 257 citations

A Monocyte Conditioned Medium Is More Effective Than Defined Cytokines in Mediating the Terminal Maturation of Human Dendritic Cells

1997 • 256 citations

Human B Lymphocytes: Phenotype, Proliferation, and Differentiation

1992 • 255 citations

Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments

1990 • 254 citations

Microanatomy of Lymphoid Tissue During Humoral Immune Responses: Structure Function Relationships

1989 • 253 citations

Ultraviolet B radiation converts Langerhans cells from immunogenic to tolerogenic antigen-presenting cells. Induction of specific clonal anergy in CD4+ T helper 1 cells.

1991 • 251 citations

Production of IL‐10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma

1994 • 248 citations

Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation.

1997 • 247 citations

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

1996 • 245 citations

Interleukin‐10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin‐4 and granulocyte/ macrophage‐colony‐stimulating factor

1997 • 244 citations

Human Dendritic Cells Skew Isotype Switching of CD40-activated Naive B Cells towards IgA1 and IgA2

1997 • 241 citations

Isolation and characterization of human peripheral blood dendritic cells.

1993 • 240 citations

Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- cells and maintains progenitor cells in vitro

1996 • 240 citations

Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements.

1992 • 239 citations

Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells

1998 • 239 citations

A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.

1996 • 238 citations

Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines.

1996 • 237 citations

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells.

1987 • 237 citations

Type I (CD64) and type II (CD32) Fc gamma receptor-mediated phagocytosis by human blood dendritic cells.

1996 • 235 citations

Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate

1996 • 235 citations

Induction of hapten-specific tolerance by interleukin 10 in vivo.

1994 • 232 citations

The Sequential Role of Lymphotoxin and B Cells in the Development of Splenic Follicles

1998 • 232 citations

Bone marrow-derived dendritic cells can process bacteria for MHC-I and MHC-II presentation to T cells.

1997 • 223 citations

Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells.

1995 • 223 citations

Effects of Measles, Gamma-Globulin-Modified Measles and Vaccine Measles on the Tuberculin Test

1964 • 222 citations

Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody.

1984 • 216 citations

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells.

1987 • 215 citations

Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo.

1992 • 215 citations

Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40‐ligand) and TNF‐α, but strongly enhanced by interleukin‐10

1995 • 215 citations

Critical Role of IL-12 in Dendritic Cell-Induced Differentiation of Naive B Lymphocytes

1998 • 214 citations

A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells

1995 • 214 citations

Contrasting Effects of TGF‐β1 and TNF‐α on the Development of Dendritic Cells from Progenitors in Mouse Bone Marrow

1997 • 214 citations

Tumor antigen presentation by murine epidermal cells.

1991 • 211 citations

Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.

1990 • 210 citations

Human Epidermal Langerhans Cells Undergo Profound Morphologic and Phenotypical Changes During In Vitro Culture

1990 • 210 citations

Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin‐10

1997 • 210 citations

Induction of Fc epsilon R2/CD23 on human epidermal Langerhans cells by human recombinant interleukin 4 and gamma interferon.

1989 • 209 citations

Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells.

1994 • 209 citations

Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.

1996 • 208 citations

Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells

1994 • 205 citations

flt3 Ligand in Cooperation With Transforming Growth Factor-β1 Potentiates In Vitro Development of Langerhans-Type Dendritic Cells and Allows Single-Cell Dendritic Cell Cluster Formation Under Serum-Free Conditions

1997 • 203 citations

Isolation and characterization of human tonsil dendritic cells.

1988 • 201 citations

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells.

1997 • 200 citations

CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells

1996 • 200 citations

Human Cytomegalovirus Glycoproteins

1996 • 196 citations

FLT3 Ligand Induces the Generation of Functionally Active Dendritic Cells in Mice

1997 • 193 citations

ORAL TOLERANCE FOR THE TREATMENT OF AUTOIMMUNE DISEASES

1997 • 193 citations

Neutrophil Granulocyte–committed Cells Can Be Driven to Acquire Dendritic Cell Characteristics

1998 • 192 citations

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

1997 • 188 citations

Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor.

1995 • 185 citations

Dendritic cells are critical accessory cells for thymus-dependent antibody responses in mouse and in man.

1983 • 185 citations

Induction of maturation of human blood dendritic cell precursors by measles virus is associated with immunosuppression

1997 • 182 citations

Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction.

1994 • 182 citations

Protein-Specific Helper T-Lymphocyte Formation Initiated by Dendritic Cells

1985 • 181 citations

Microchimerism, dendritic cell progenitors and transplantation tolerance

1995 • 181 citations

Isolation and characterization of dendritic cells from mouse heart and kidney.

1994 • 179 citations

The role of endosomes and lysosomes in MHC class II functioning

1998 • 179 citations

Apoptosis as a cause of death in measles virus-infected cells

1995 • 178 citations

S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis

1989 • 176 citations

Contact Allergens and Epidermal Proinflammatory Cytokines Modulate Langerhans Cell E-cadherin Expression in Situ

1996 • 176 citations

An Essential Role for CD44 Variant Isoforms in Epidermal Langerhans Cell and Blood Dendritic Cell Function

1997 • 176 citations

The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors.

1995 • 175 citations

A Skin Homing Molecule Defines the Langerhans Cell Progenitor in Human Peripheral Blood

1997 • 173 citations

Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes.

1996 • 173 citations

Dendritic cells in Leishmania major‐immune mice harbor persistent parasites and mediate an antigen‐specific T cell immune response

1995 • 172 citations

Tumor necrosis factor-alpha strongly potentiates interleukin-3 and granulocyte-macrophage colony-stimulating factor-induced proliferation of human CD34+ hematopoietic progenitor cells

1990 • 171 citations

Extramedullary Expansion of Hematopoietic Progenitor Cells in Interleukin (IL)-6–sIL-6R Double Transgenic Mice

1997 • 171 citations

Dendritic Cells Express Multiple Chemokine Receptors Used as Coreceptors for HIV Entry

1998 • 167 citations

Changes in Cytokine Production after Measles Virus Vaccination: Predominant Production of IL-4 Suggests Induction of a Th2 Response

1993 • 167 citations

Induction of IL-15 messenger RNA and protein in human blood-derived dendritic cells: a role for IL-15 in attraction of T cells.

1997 • 167 citations

Human dendritic cells phagocytose and process Borrelia burgdorferi.

1996 • 166 citations

The antigen-presenting activities of Ia+ dendritic cells shift dynamically from lung to lymph node after an airway challenge with soluble antigen.

1995 • 166 citations

Immune Responses During Measles Virus Infection

1995 • 165 citations

Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures.

1991 • 165 citations

Programmed Cell Death (Apoptosis) in Human Monocytes Infected by Influenza A Virus

1994 • 164 citations

Thymic dendritic cells

1997 • 163 citations

Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression.

1995 • 162 citations

Localization of Kaposi's Sarcoma–Associated Herpesvirus in Bone Marrow Biopsy Samples From Patients With Multiple Myeloma

1997 • 162 citations

Memory B Cells Are Biased Towards Terminal Differentiation: A Strategy That May Prevent Repertoire Freezing

1997 • 161 citations

Pathogenesis Of Measles Virus Infection: An Hypothesis For Altered Immune Responses

1994 • 161 citations

CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells

1997 • 161 citations

Rat Spleen Dendritic Cells Express Natural Killer Cell Receptor Protein 1 (NKR-P1) and Have Cytotoxic Activity to Select Targets via a Ca2+-dependent Mechanism

1997 • 159 citations

Thymocytes appear to ignore class I major histocompatibility complex antigens expressed on thymus epithelial cells

1984 • 158 citations

CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells

1997 • 156 citations

Interleukin‐12 Production by Dendritic Cells

1996 • 155 citations

Parasitism of Epidermal Langerhans Cells in Experimental Cutaneous Leishmaniasis withLeishmania major

1993 • 153 citations

Interleukin‐10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells

1994 • 151 citations

CYTOMEGALOVIRUS INFECTION ASSOCIATED WITH AND PRECEDING CHRONIC GRAFT-VERSUS-HOST DISEASE

1984 • 148 citations

Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice.

1996 • 147 citations

Enhancement of Tumor Outgrowth Through CTL Tolerization After Peptide Vaccination Is Avoided by Peptide Presentation on Dendritic Cells

1998 • 145 citations

Immunogenicity of retransplanted rat kidney allografts. Effect of inducing chimerism in the first recipient and quantitative studies on immunosuppression of the second recipient.

1982 • 145 citations

The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored byin vitrophotorepair of cyclobutane pyrimidine dimers

1997 • 144 citations

LOCALIZATION OF HLA-ABC AND DR ANTIGENS IN HUMAN KIDNEY

1981 • 144 citations

TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes.

1986 • 144 citations

Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses.

1993 • 142 citations

Cutting Edge: Physical Interaction Between Dendritic Cells and Tumor Cells Results in an Immunogen That Induces Protective and Therapeutic Tumor Rejection

1998 • 141 citations

Functional CD40 ligand expressed by human blood dendritic cells is up-regulated by CD40 ligation.

1996 • 140 citations

A Novel Migration Pathway for Rat Dendritic Cells from the Blood: Hepatic Sinusoids–Lymph Translocation

1997 • 140 citations

Susceptibility of mononuclear phagocytes to influenza A virus infection and possible role in the antiviral response

1997 • 138 citations

The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells.

1985 • 138 citations

Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation

1995 • 138 citations

Induction of CD8⁺ cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells

1993 • 138 citations

Nuclear localization of RelB is associated with effective antigen-presenting cell function.

1997 • 137 citations

T-zone histiocytes in adenocarcinoma of the lung in relation to postoperative prognosis

1985 • 136 citations

CD154/CD40 and CD70/CD27 interactions have different and sequential functions in T cell-dependent B cell responses: enhancement of plasma cell differentiation by CD27 signaling.

1997 • 136 citations

Dendritic cells in normal and asthmatic airways: expression of the α subunit of the high affinity immunoglobulin E receptor (FcεRI‐α)

1996 • 136 citations

Follicular Dendritic Cells Specifically Express the Long CR2/CD21 Isoform

1997 • 136 citations

Dendritic cells hold promise for immunotherapy

1997 • 135 citations

Distinct Roles of Lymphotoxin α and the Type I Tumor Necrosis Factor (TNF) Receptor in the Establishment of Follicular Dendritic Cells from Non–Bone Marrow–derived Cells

1997 • 131 citations

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection

1994 • 128 citations

IgE-Mediated Allergen Presentation via Fc Epsilon Rl on Antigen-Presenting Cells

1997 • 128 citations

Human Immunodeficiency Virus-1 Entry Into Purified Blood Dendritic Cells Through CC and CXC Chemokine Coreceptors

1997 • 128 citations

Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis.

1985 • 128 citations

Dendritic cells and tolerance induction

1996 • 128 citations

Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes.

1992 • 128 citations

Localization of 125I-Labeled Antigen in Germinal Centers of Mouse Spleen: Histologic and Ultrastructural Autoradiographic Studies of the Secondary Immune Reaction

1968 • 127 citations

Split activity of interleukin‐10 on antigen capture and antigen presentation by human dendritic cells: Definition of a maturative step

1997 • 126 citations

Follow-up evaluation of prostate cancer patients infused with autologous dendritic cells pulsed with PSMA peptides

1997 • 126 citations

Intrathymic presentation of circulating non-MHC antigens by medullary dendritic cells. An antigen-dependent microenvironment for T cell differentiation.

1986 • 126 citations

Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells.

1997 • 125 citations

Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells

1997 • 125 citations

Dendritic/Langerhans Cells and Prognosis in Patients with Papillary Thyroid Carcinomas: Immunocytochemical Study of 106 Thyroid Neoplasms Correlated to Follow-up Data

1988 • 125 citations

Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes.

1994 • 124 citations

Antigen processing and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function.

1989 • 122 citations

MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.

1995 • 122 citations

Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo.

1995 • 121 citations

Presentation of prostate tumor antigens by dendritic cells stimulates T-cell proliferation and cytotoxicity

1996 • 120 citations

ANTIGENS IN IMMUNITY

1968 • 119 citations

Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.

1983 • 118 citations

The ultrastructure of antigen localization and virus-like particles in mouse spleen germinal centers

1968 • 117 citations

Interleukin-3 cooperates with tumor necrosis factor alpha for the development of human dendritic/Langerhans cells from cord blood CD34+ hematopoietic progenitor cells

1996 • 117 citations

Intraepithelial airway dendritic cells: a distinct subset of pulmonary dendritic cells obtained by microdissection.

1992 • 116 citations

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia.

1995 • 115 citations

TGF-beta 1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis.

1997 • 115 citations

The Actin-Bundling Protein Fascin Is Involved in the Formation of Dendritic Processes in Maturing Epidermal Langerhans Cells

1998 • 115 citations

Histiocytes in nasopharyngeal carcinoma in relation to prognosis

1986 • 114 citations

Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells.

1993 • 112 citations

FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver

1995 • 112 citations

Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy.

1990 • 112 citations

Isolated follicular dendritic cells: cytochemical antigen localization, Nomarski, SEM, and TEM morphology.

1985 • 111 citations

Prevention of Peripheral Tolerance by a Dendritic Cell Growth Factor: Flt3 Ligand as an Adjuvant

1998 • 110 citations

Phenotypic and functional characterization of CD11c⁺ dendritic cell population in mouse Peyer's patches

1996 • 110 citations

Establishment of a cell line with features of early dendritic cell precursors from fetal mouse skin

1995 • 109 citations

Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer

1990 • 108 citations

Human dendritic Langerhans cells generated in vitro from CD34+ progenitors can prime naive CD4+ T cells and process soluble antigen.

1995 • 107 citations

Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells

1996 • 107 citations

HLA class I specific inhibitory receptors

1997 • 107 citations

Isolation of Human Blood Dendritic Cells Using the CMRF-44 Monoclonal Antibody: Implications for Studies on Antigen-Presenting Cell Function and Immunotherapy

1997 • 107 citations

Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells

1993 • 107 citations

Dendritic Cells as Antigen Presenting Cellsin Vivo

1990 • 104 citations

Quantitation of Surface Antigens on Cultured Murine Epidermal Langerhans Cells: Rapid and Selective Increase in the Level of Surface MHC Products

1988 • 103 citations

Different pathways of differentiation of pre-B cell lines are induced by dendritic cells and T cells from different lymphoid tissues

1986 • 103 citations

Viral Superantigen Drives Extrafollicular and Follicular B Cell Differentiation Leading to Virus-specific Antibody Production

1997 • 102 citations

Chemokines: a superfamily of chemotactic cytokines

1996 • 101 citations

A novel mechanism of glucocorticoid-induced immune suppression: the inhibiton of T cell-mediated terminal maturation of a murine dendritic cell line.

1996 • 99 citations

B Cell Growth and Differentiation Factors and Mechanism of B Cell Activation

1984 • 99 citations

Generation of dendritic cells from bone marrow progenitors using GM‐CSF, TNF‐α, and additional cytokines: antagonistic effects of IL‐4 and IFN‐γ and selective involvement of TNF‐α receptor‐1

1997 • 96 citations

Regulation of IgE production in pre‐sensitized animals: in vivo elimination of alveolar macrophages preferentially increases IgE responses to inhaled allergen*

1992 • 96 citations

Interferon‐γ and interleukin‐10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 (B7‐1) expression

1996 • 96 citations

CYTOMEGALOVIRUS-INDUCED CD13-SPECIFIC AUTOIMMUNITY-A POSSIBLE CAUSE OF CHRONIC GRAFT-VERSUS-HOST DISEASE1

1996 • 96 citations

Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo.

1995 • 95 citations

Characterization of accessory molecules in murine lung dendritic cell function: roles for CD80, CD86, CD54, and CD40L.

1997 • 94 citations

Cells expressing Ia antigens in the avian thymus.

1984 • 93 citations

The CD40–CD154 system in anti-infective host defense

1997 • 91 citations

Costimulator dependence of lymphokine secretion by naive and activated CD4+ T lymphocytes from TCR transgenic mice.

1994 • 91 citations

FcεRI-expressing antigen-presenting cells: new players in the atopic game

1997 • 89 citations

Dendritic cells produce macrophage inflammatory protein-1 gamma, a new member of the CC chemokine family.

1996 • 89 citations

Role of IL-12 in human B lymphocyte proliferation and differentiation.

1995 • 89 citations

Dual Role of Dendritic Cells in the Induction and Down-Regulation of Antigen-Specific Cutaneous Inflammation

1998 • 89 citations

Dendritic cells are potent antigen-presenting cells for microbial superantigens.

1992 • 89 citations

Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction

1988 • 87 citations

Human interdigitating dendritic cells directly stimulate CD40‐activated naive B cells

1997 • 87 citations

Polymerase Chain Reaction Selects a Novel Disintegrin Proteinase from CD40-Activated Germinal Center Dendritic Cells

1997 • 86 citations

Follicular dendritic cells inhibit apoptosis in human B lymphocytes by a rapid and irreversible blockade of preexisting endonuclease.

1995 • 86 citations

Dendritic Cells in the Respiratory Tract

1990 • 85 citations

Human Langerhans Cells Express E-Cadherin

1995 • 83 citations

Regulation of the High Affinity Receptor for IgE on Human Epidermal Langerhans Cells

1998 • 82 citations

Intercellular adhesion molecule‐3 is the predominant co‐stimulatory ligand for leukocyte function antigen‐1 on human blood dendritic cells

1995 • 81 citations

Langerhans’ cells produce type IV collagenase (MMP‐9) following epicutaneous stimulation with haptens

1997 • 81 citations

Human Dermal Dendritic Cells Process and Present Soluble Protein Antigens

1998 • 79 citations

Dendritic Cells and Resting B Cells Form Clusters In Vitro and In Vivo: T Cell Independence, Partial LFA-1 Dependence, and Regulation by Cross-Linking Surface Molecules

1998 • 78 citations

Expression of CD86 on Human Marrow CD34+ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells

1998 • 77 citations

Involvement of Dihydropyridine-sensitive Calcium Channels in Human Dendritic Cell Function

1998 • 77 citations

Natural killer cell receptors and MHC class I interactions

1997 • 77 citations

Expression of gp40, the murine homologue of human epithelial cell adhesion molecule (Ep‐CAM), by murine dendritic cells

1996 • 77 citations

Two populations of splenic dendritic cells detected with M342, a new monoclonal to an intracellular antigen of interdigitating dendritic cells and some B lymphocytes

1992 • 76 citations

The Central Role of Follicular Dendritic Cells in Lymphoid Tissues

1992 • 75 citations

Migration of Dendritic Cells into the Draining Lymph Nodes of the Lung after Intratracheal Instillation

1993 • 73 citations

FACS Purification of Bone Marrow-Derived Epidermal Populations in Mice: Langerhans Cells and Thy-1+ Dendritic Cells

1985 • 72 citations

Phorbol Esters Induce Differentiation of Human CD34+ Hemopoietic Progenitors to Dendritic Cells: Evidence for Protein Kinase C-Mediated Signaling

1998 • 72 citations

Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells

1994 • 71 citations

Immunohistochemical, electron microscopic and in situ hybridization evidence for the involvement of lymphatics in the spread of HIV-1

1988 • 70 citations

Interferon-gamma enhances factor-dependent myeloid proliferation of human CD34+ hematopoietic progenitor cells

1992 • 69 citations

Colony-stimulating factor-1 secreted by fibroblasts promotes the growth of dendritic cell lines (XS series) derived from murine epidermis.

1995 • 69 citations

IL-12-induced up-regulation of NKRP1A expression in human NK cells and consequent NKRP1A- mediated down-regulation of NK cell activation

1998 • 69 citations

Follicular dendritic cells (FDC) in retroviral infection: host/pathogen perspectives

1997 • 68 citations

Human Resident Langerhans Cells Display a Lysosomal compartment Enriched in MHC Class II

1994 • 68 citations

Interleukin 12 alters the isotype-restricted antibody response of mice to hen eggwhite lysozyme

1995 • 67 citations

Modulation of airway intraepithelial dendritic cells following exposure to steroids.

1995 • 66 citations

The Regulation of Pulmonary Immunity

1995 • 65 citations

The roles of interdigitating cells and natural killer cells in the rapid rejection of allogeneic lymphocytes

1986 • 65 citations

The pathobiology of HIV infection

1992 • 61 citations

Heat-inactivated Sendai virus can enter multiple MHC class I processing pathways and generate cytotoxic T lymphocyte responses in vivo.

1995 • 59 citations

Human follicular dendritic cells enhance cytokine-dependent growth and differentiation of CD40-activated B cells.

1995 • 58 citations

Blood Dendritic Cells From Myeloma Patients Are Not Infected With Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8)

1998 • 58 citations

Cytomegalovirus and atherosclerosis

1995 • 56 citations

Fetal skin-derived MHC class I+, MHC class II- dendritic cells stimulate MHC class I-restricted responses of unprimed CD8+ T cells.

1994 • 55 citations

Conditional ablation of dendritic cells in transgenic mice.

1994 • 55 citations

Enhancement of Humoral Immunity by Interleukin‐12

1996 • 52 citations

Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ

1996 • 51 citations

In vitro propagated dendritic cells from prostate cancer patients as a component of prostate cancer immunotherapy

1995 • 51 citations

Expression and function of NKRP1A molecule on human monocytes and dendritic cells

1997 • 51 citations

Tumor necrosis factor alpha cooperates with interleukin 3 in the recruitment of a primitive subset of human CD34+ progenitors.

1993 • 50 citations

Role of dendritic cells in immunopathogenesis of human immunodeficiency virus infection

1997 • 48 citations

Frequency of herpes simplex virus-specific murine cytotoxic T lymphocyte precursors in mitogen- and antigen-driven primary in vitro T cell responses.

1987 • 48 citations

Dendritic cells support production of IgA and other non-IgM isotypes in clonal microculture

1990 • 47 citations

Murine epidermal Langerhans cells are potent stimulators of an antigen‐specific T cell response to Leishmania major, the cause of cutaneous leishmaniasis

1992 • 47 citations

E-cadherin-mediated adhesion involving Langerhans cell-like dendritic cells expanded from murine fetal skin.

1997 • 47 citations

Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules

1997 • 46 citations

Mechanisms involved in uptake of Bordetella bronchiseptica by mouse dendritic cells

1994 • 45 citations

Production of Interferon‐α/β by Murine Dendritic Cell Lines Stimulated by Virus and Bacteria

1997 • 44 citations

Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes.

1996 • 44 citations

Role of annexins in endocytosis of antigens in immature human dendritic cells

1997 • 43 citations

Induction of Peripheral Tolerance by Intrathymic Inoculation of Soluble Alloantigens: Evidence for the Role of Host Antigen-Presenting Cells and Suppresser Cell Mechanism

1995 • 43 citations

The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells

1997 • 42 citations

Expression of B7 Costimulator Molecules on Mouse Dendritic Cells

1995 • 40 citations

The Role of Antigen-Presenting Cells in the Regulation of Delayed-Type Hypersensitivity

1993 • 40 citations

Assessment of CD4 expression by early T precursor cells and by dendritic cells in the human thymus.

1994 • 39 citations

Evidence for Th2-type T helper cell control of allergic disease in vivo

1993 • 39 citations

Distinctive dendritic cell subsets expressing factor XIIIa, CD1a, CD1b and CD1c in mycosis fungoides and psoriasis

1995 • 39 citations

High-dose UV-B radiation alters human dendritic cell costimulatory activity but does not allow dendritic cells to tolerize T lymphocytes to alloantigen in vitro

1993 • 38 citations

Intercellular Adhesion Molecule-2 (ICAM-2) Expression on Human Dendritic Cells

1993 • 38 citations

CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamily

1998 • 37 citations

Differential effects of interleukin‐10 on the expression of HLA class II and CD1 molecules induced by granulocyte/macrophage colony‐stimulating factor/interleukin‐4

1995 • 37 citations

Enhancement of antibody response by mouse dendritic cells pulsed with tobacco mosaic virus or with rabbit antiidiotypic antibodies raised against a private rabbit idiotype.

1985 • 37 citations

Expression and function of CD80 and CD86 costimulator molecules on synovial dendritic cells in chronic arthritis

1996 • 36 citations

Dendritic cells in synovial fluid of chronic inflammatory arthritis lack CD80 surface expression

1995 • 34 citations

Virus-lymphoid cell interactions

1996 • 33 citations

Biology and potential clinical applications of flt3 ligand

1995 • 33 citations

Priming for a Cytotoxic Response to Minor Histocompatibility Antigens: Antigen Specificity and Failure to Demonstrate a Carrier Effect

1977 • 33 citations

ACCEPTANCE OF MURINE THYROID ALLOGRAFTS BY PRETREATMENT OF ANTI-Ia ANTIBODY OR ANTI-DENDRITIC CELL ANTIBODY IN VITRO

1989 • 32 citations

The furture of transplantation: With particular reference to chimerism and xenotransplantation

1997 • 30 citations

The role of CD1 molecules in immune responses to infection

1997 • 30 citations

Langerhans cells in human lung tumours: an immunohistological study

1989 • 30 citations

Mechanisms of loss of functional dendritic cells in HIV-1 infection

1997 • 30 citations

Comparing macrophages and dendritic leukocytes as antigen‐presenting cells for humoral responses in vivo by antigen targeting

1994 • 30 citations

The human thymic dendritic cell phenotype and its modification in culture

1992 • 30 citations

Immunological tolerance to a defined myelin basic protein antigen administered intrathymically.

1994 • 29 citations

Treatment with monoclonal anti-CD3 antibody protects against lethal Sendai virus infection by induction of natural killer cells.

1990 • 29 citations

Effect of low dose UVB irradiation on the migratory properties and functional capacities of human skin dendritic cells

1996 • 26 citations

In Vitro Effect of Interleukin-12 on Antigen-Specific Lymphocyte Proliferative Responses from Persons Infected with Human Immunodeficiency Virus Type 1

1996 • 26 citations

MHC Class I+/II− Dendritic Cells Induce Hapten-Specific Immune Responses In Vitro and In Vivo

1997 • 25 citations

Fc∈RI Mediates IgE Binding to Human Epidermal Langerhans Cells

1992 • 25 citations

Murine Retrovirus Induces Defects in the Function of Dendritic Cells at Early Stages of Infection

1994 • 24 citations

Regulation of ocular immune responses

1997 • 22 citations

Costimulatory molecule-deficient dendritic cell progenitors induce T cell hyporesponsiveness in vitro prolong the survival of vascularized cardiac allografts

1997 • 21 citations

Correction

1986 • 20 citations

A Potential Pathway of Th2 Development during Primary Immune Response

1997 • 19 citations

CD34+CD38−lin− Cord Blood Cells Develop into Dendritic Cells in Human Thymic Stromal Monolayers and Thymic Nodules

1998 • 18 citations

Langerhans Cells, Antigen Presentation, and the Diversity of Responses to Chemical Allergens

1992 • 16 citations

Pulmonary Dendritic Cell Populations

1993 • 15 citations

MHC Class I Expression on Dendritic Cells Is Sufficient to Sensitize for Transplantation Immunity

1996 • 15 citations

Primary Human Immune Response to Neisseria meningitidis Serogroup C in Interleukin-12--Treated Severe Combined Immunodeficient Mice Engrafted with Human Peripheral Blood Lymphocytes

1997 • 15 citations

Development of Components of the Mucosal Immune System in Scid Recipient Mice

1994 • 15 citations

Dendritic Cell Dependent Expression of IgA By Clones in T/B Microcultures

1993 • 13 citations

Polymerase chain reaction‐based identification of a novel serpin from human dendritic cells

1997 • 13 citations

Interleukin‐12 up‐regulates the induction of an antigen‐specific antibody response in cultures of human lymphocytes

1997 • 9 citations

The follicular dendritic cell: possible regulatory roles of associated molecules

1991 • 8 citations

Interaction Through the Lfa-1/Icam-1 Pathway Prevents Programmed Cell Death of Germinal Center B Cells

1993 • 7 citations

Improved Isolation of Dendritic Cells in Chronic Arthritic Joints Reveals No B7 (CD80) Surface Expression

1995 • 3 citations