Comparing macrophages and dendritic leukocytes as antigen‐presenting cells for humoral responses in vivo by antigen targeting

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

The Heterogeneity of Mononuclear Phagocytes in Lymphoid Organs: Distinct Macrophage Subpopulations in Rat Recognized by Monoclonal Antibodies ED1, ED2 and ED3

1985 • 1,605 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ.

1990 • 670 citations

Diversity of Cytokine Synthesis and Function of Mouse CD4⁺ T Cells

1991 • 371 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo.

1992 • 215 citations

Heterogeneity of Macrophages in the Rat Evidenced by Variability in Determinants: Two New Anti-Rat Macrophage Antibodies Against a Heterodimer of 160 and 95 kd (CD11/CD18)

1989 • 130 citations

Adjuvant-free IgG responses induced with antigen coupled to antibodies against class II MHC

1987 • 125 citations

The alternative antigen pathway

1989 • 119 citations

Targeting autoantigen to B cells prevents the induction of a cell-mediated autoimmune disease in rats.

1992 • 94 citations

The Architecture of Rat Lymph Nodes.

1980 • 88 citations

Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin.

1986 • 85 citations

Induction of anti-tobacco mosaic virus antibodies in mice by rabbit antiidiotypic antibodies.

1984 • 65 citations

Efficiency of antigen presentation after antigen targeting to surface IgD, IgM, MHC, Fc gamma RII, and B220 molecules on murine splenic B cells.

1989 • 60 citations

Enhanced T cell responses to antigenic peptides targeted to B cell surface Ig, Ia, or class I molecules.

1988 • 54 citations

Macrophages as accessory cells in the in vivo humoral immune response: from processing of particulate antigens to regulation by suppression.

1992 • 40 citations

Adjuvant-independent immunization by immunotargeting antigens to MHc and non-MHc determinants in vivo

1991 • 37 citations

Antigen presentation by B lymphocytes to CD4+ T lymphocytes in vivo: importance for B lymphocyte and T lymphocyte activation.

1992 • 31 citations

Modulation of immune responses with monoclonal antibodies. I. Effects on regional lymph node morphology and on anti‐hapten responses to haptenized monoclonal antibodies

1990 • 9 citations

Antigen targetting with monoclonal antibodies as vectors—II. Further evidence that conjugation of antigen to specific monoclonal antibodies enhances uptake by antigen presenting cells

1991 • 7 citations