Dendritic Cells Express Multiple Chemokine Receptors Used as Coreceptors for HIV Entry

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

1996 • 3,106 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1996 • 2,502 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1996 • 1,678 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1993 • 1,450 citations

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

1990 • 1,378 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

High Levels of HIV-1 in Plasma During All Stages of Infection Determined By Competitive PCR

1993 • 1,263 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1997 • 923 citations

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

1995 • 756 citations

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques.

1996 • 705 citations

Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene

1996 • 701 citations

Expression cloning of new receptors used by simian and human immunodeficiency viruses

1997 • 692 citations

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

1996 • 669 citations

Relative resistance to HIV–1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high–risk sexual exposures

1996 • 656 citations

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.

1996 • 626 citations

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

1996 • 561 citations

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

1997 • 489 citations

Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.

1997 • 474 citations

Inherited Resistance to HIV-1 Conferred by an Inactivating Mutation in CC Chemokine Receptor 5: Studies in Populations with Contrasting Clinical Phenotypes, Defined Racial Background, and Quantified Risk

1997 • 423 citations

Molecular Cloning of Human Eotaxin, an Eosinophil-selective CC Chemokine, and Identification of a Specific Eosinophil Eotaxin Receptor, CC Chemokine Receptor 3

1996 • 412 citations

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.

1997 • 388 citations

STRL33, A Novel Chemokine Receptor–like Protein, Functions as a Fusion Cofactor for Both Macrophage-tropic and T Cell Line–tropic HIV-1

1997 • 378 citations

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1997 • 357 citations

Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.

1993 • 349 citations

Chemokine receptors: Structure, function and role in microbial pathogenesis

1996 • 329 citations

Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.

1995 • 318 citations

Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1α, MIP-1β, and RANTES

1996 • 301 citations

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection

1997 • 295 citations

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse.

1993 • 265 citations

Cloning and Functional Expression of a Human Eosinophil CC Chemokine Receptor

1995 • 246 citations

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

1996 • 245 citations

Recent advances in the study of dendritic cells and follicular dendritic cells

1995 • 191 citations

Role of Lymphoid Organs in the Pathogenesis of Human Immunodeficiency Virus (HIV) Infection

1994 • 188 citations

Human Immunodeficiency Virus-1 Entry Into Purified Blood Dendritic Cells Through CC and CXC Chemokine Coreceptors

1997 • 128 citations

Homozygous Δ32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient

1997 • 122 citations

Dendritic Cells in Fundamental and Clinical Immunology

1995 • 108 citations

Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells

1996 • 107 citations

Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons.

1995 • 96 citations

TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function

1997 • 88 citations

Morphology and phenotype of dendritic cells from peripheral blood and their productive and non-productive infection with human immunodeficiency virus type 1.

1991 • 73 citations

A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB)

1997 • 68 citations

The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro.

1996 • 60 citations

Acutely Infected Langerhans Cells Are More Efficient than T Cells in Disseminating HIV Type 1 to Activated T Cells Following a Short Cell-Cell Contact

1995 • 51 citations

Antiretroviral effect of zidovudine–didanosine combination on blood and lymph nodes

1997 • 43 citations

Trypsin-resistant gp120 receptors are upregulated on short-term cultured human epidermal Langerhans cells

1991 • 21 citations

Dendritic Cells “in Vivo”: Migration and Antigen Handling

1993 • 9 citations