Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.

1994 • 866 citations

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

1995 • 687 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

Interactions of tumor necrosis factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34+ progenitors in human bone marrow.

1992 • 452 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.

1993 • 428 citations

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny.

1996 • 405 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Identification of dendritic cell colony-forming units among normal human CD34+ bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.

1995 • 296 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

Guidebook to Cytokines and Their Receptors

1995 • 273 citations

Generation of human dendritic cells/Langerhans cells from circulating CD34+ hematopoietic progenitor cells

1996 • 259 citations

Propagation of dendritic cell progenitors from normal mouse liver using granulocyte/macrophage colony-stimulating factor and their maturational development in the presence of type-1 collagen.

1994 • 247 citations

A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.

1996 • 238 citations

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

1993 • 233 citations

Identification of hematopoietic progenitors of macrophages and dendritic Langerhans cells (DL-CFU) in human bone marrow and peripheral blood

1990 • 186 citations

Dendritic cells from mouse bone marrow: In vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor

1992 • 179 citations

T-cell lineage commitment and cytokine responses of thymic progenitors

1995 • 164 citations

Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation

1995 • 138 citations

Mechanisms of tumor necrosis factor-granulocyte-macrophage colony- stimulating factor-induced dendritic cell development

1993 • 92 citations

Accessory Cells with a Morphology and Marker Pattern of Dendritic Cells can be Obtained from Elutriator-Purified Blood Monocyte Fractions.An Enhancing Effect of Metrizamide in this Differentiation

1989 • 67 citations

Development of a Langerhans cell phenotype from peripheral blood monocytes

1992 • 63 citations

CD4 and CD8 expression by human and mouse thymic dendritic cells

1994 • 59 citations

In Vitro Regulation of Dendritic Cell Development and Function

1996 • 37 citations

CD4 and CD8 expression and T cell antigen receptor gene rearrangement in early intrathymic precursor cells

1996 • 36 citations

Induction of limited growth and differentiation of early thymic precursor cells by thymic epithelial cell lines

1995 • 9 citations