Interleukin-3 cooperates with tumor necrosis factor alpha for the development of human dendritic/Langerhans cells from cord blood CD34+ hematopoietic progenitor cells

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis

1994 • 883 citations

Epidermal Langerhans cells are derived from cells originating in bone marrow

1979 • 879 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

Cytokine Receptors and Signal Transduction

1992 • 607 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells.

1988 • 565 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

Interactions of tumor necrosis factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34+ progenitors in human bone marrow.

1992 • 452 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.

1993 • 428 citations

Anti-leu-3/T4 antibodies react with cells of monocyte/macrophage and langerhans lineage

1984 • 426 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Dendritic cells and macrophages are required for Th1 development of CD4⁺ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-_γ production is IFN-_γ-dependent

1993 • 346 citations

Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication.

1983 • 300 citations

Cytokine Receptors and Signal Transduction

1997 • 259 citations

TNF in combination with GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages

1992 • 257 citations

Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements.

1992 • 239 citations

Activation of human B lymphocytes through CD40 and interleukin 4

1989 • 227 citations

Interleukin-3 supports growth of mouse pre-B-cell clones in vitro

1984 • 213 citations

Isolation and characterization of human tonsil dendritic cells.

1988 • 201 citations

Bone marrow origin of Ia-positive cells in the medulla rat thymus.

1981 • 197 citations

Relation between Langerhans Cells, Veiled Cells, and Interdigitating Cells

1982 • 194 citations

CD1 molecule expression on human monocytes induced by granulocyte-macrophage colony-stimulating factor.

1993 • 183 citations

Identity of differentiation inducing factor and tumour necrosis factor

1986 • 181 citations

Dendritic cells from mouse bone marrow: In vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor

1992 • 179 citations

Tumor necrosis factor-alpha strongly potentiates interleukin-3 and granulocyte-macrophage colony-stimulating factor-induced proliferation of human CD34+ hematopoietic progenitor cells

1990 • 171 citations

Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions.

1982 • 168 citations

Human B cell precursors proliferate and express CD23 after CD40 ligation.

1993 • 123 citations

Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells

1993 • 107 citations

Potentiation of early hematopoiesis by tumor necrosis factor-alpha is followed by inhibition of granulopoietic differentiation and proliferation

1991 • 90 citations

Proliferative effect of interleukin-3 on normal and leukemic human B cell precursors.

1989 • 72 citations

Human epidermal Langerhans cells express only the 40-kilodalton Fc gamma receptor (FcRII).

1990 • 69 citations

Activation of human eosinophil and neutrophil functions by haematopoietic growth factors: comparisons of IL‐1, IL‐3, IL‐5 and GM‐CSF

1992 • 67 citations

Combined and sequential effects of human IL-3 and GM-CSF on the proliferation of CD34+ hematopoietic cells from cord blood

1989 • 67 citations

Mouse monoclonal antibodies to the human C3b receptor

1985 • 56 citations

Tumor necrosis factor alpha cooperates with interleukin 3 in the recruitment of a primitive subset of human CD34+ progenitors.

1993 • 50 citations

Proliferation and differentiation of human CD5⁺ and CD5⁻ B cell subsets activated through their antigen receptors or CD40 antigens

1992 • 48 citations

Differentiation-inducing effect of recombinant human tumor necrosis factor alpha and gamma-interferon in vitro on blast cells from patients with acute myeloid leukemia and myeloid blast crisis of chronic myeloid leukemia.

1989 • 45 citations

Granulocyte-macrophage-colony stimulating factor

1988 • 36 citations

Human recombinant IL-3 is a growth factor for normal B cells.

1992 • 34 citations

Ontogeny of langerhans cells: Phenotypic differentiation from the bone marrow to the skin

1990 • 11 citations