Dendritic cells are potent antigen-presenting cells for microbial superantigens.

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins

1989 • 711 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

Identification and Characterization of an Exotoxin from Staphylococcus aureus Associated with Toxic-Shock Syndrome

1981 • 668 citations

Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain.

1981 • 589 citations

Superantigens interact with MHC class II molecules outside of the antigen groove

1990 • 438 citations

T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells.

1988 • 427 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Human dendritic cells. Enrichment and characterization from peripheral blood

1982 • 389 citations

High-affinity binding of staphylococcal enterotoxins A and B to HLA-DR

1989 • 388 citations

Cultured Human Langerhans Cells Resemble Lymphoid Dendritic Cells in Phenotype and Function

1989 • 376 citations

Selective expansion of T cells expressing V beta 2 in toxic shock syndrome.

1990 • 359 citations

T‐Cell Responses to Mls and to Bacterial Proteins that Mimic its Behavior^#

1989 • 337 citations

Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication.

1983 • 300 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

Class II MHC Molecules Are Specific Receptors for Staphylococcus Enterotoxin A

1989 • 267 citations

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.

1990 • 253 citations

Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon.

1988 • 221 citations

Binding of staphylococcal enterotoxin A to accessory cells is a requirement for its ability to activate human T cells.

1988 • 187 citations

Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells.

1991 • 187 citations

Binding of staphylococcal enterotoxin A to HLA-DR on B cell lines.

1989 • 169 citations

Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions.

1982 • 168 citations

Engagement of major histocompatibility complex class II molecules induces sustained, lymphocyte function-associated molecule 1-dependent cell adhesion.

1990 • 163 citations

Toxic shock syndrome toxin 1 binds to major histocompatibility complex class II molecules.

1989 • 139 citations

Induction of Human Interleukin-l by Toxic-Shock-Syndrome Toxin-1

1985 • 138 citations

Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC.

1990 • 130 citations

Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis.

1985 • 128 citations

An evolutionary conserved mechanism of T cell activation by microbial toxins. Evidence for different affinities of T cell receptor-toxin interaction.

1991 • 126 citations

Production of Tumor Necrosis Factor by Human Monocytes in Response to Toxic-Shock-Syndrome Toxin-1

1988 • 108 citations

Staphylococcal enterotoxin B and toxic shock syndrome toxin-1 bind to distinct sites on HLA-DR and HLA-DQ molecules.

1989 • 105 citations

The α1 domain of the HLA-DR molecule is essential for high-affinity binding of the toxic shock syndrome toxin-1

1990 • 100 citations

The staphylococcal toxic shock syndrome toxin 1 triggers B cell proliferation and differentiation via major histocompatibility complex-unrestricted cognate T/B cell interaction.

1989 • 96 citations

Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction

1988 • 87 citations

Activation of murine T cells by toxic shock syndrome toxin-1. The toxin-binding structures expressed on murine accessory cells are MHC class II molecules.

1989 • 70 citations

Migration patterns of dendritic leukocytes

1989 • 66 citations

Ontogeny of non-lymphoid and lymphoid cells in the rat gut with special reference to large mononuclear Ia-positive dendritic cells.

1983 • 63 citations

Stimulation of mouse lymphocytes by a mitogen derived from Mycoplasma arthritidis. V. A small basic protein from culture supernatants is a potent T cell mitogen.

1986 • 57 citations