In vitro propagated dendritic cells from prostate cancer patients as a component of prostate cancer immunotherapy

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

LNCaP model of human prostatic carcinoma.

1983 • 1,749 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.

1990 • 561 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.

1994 • 276 citations

Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro.

1990 • 269 citations

Human peripheral blood dendritic cell subsets. Isolation and characterization of precursor and mature antigen-presenting cells.

1994 • 252 citations

Isolation and characterization of human peripheral blood dendritic cells.

1993 • 240 citations

Costimulation of T-cell growth

1992 • 225 citations

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells.

1987 • 215 citations

Non-adherent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology.

1986 • 211 citations

Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.

1990 • 210 citations

Antigen-presenting cell types

1993 • 179 citations

Human tumor-infiltrating lymphocytes: a marker of host response.

1985 • 166 citations

Generation of antigen-specific CD8+ CTLs from naive precursors.

1994 • 143 citations

A quantitative analysis of antigen-presenting cell function: activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing costimulation.

1994 • 133 citations

Chapter 4 Lipid Vesicles as Carriers for Introducing Biologically Active Materials into Cells

1976 • 131 citations

Dendritic cells are the most efficient in presenting endogenous naturally processed self-epitopes to class II-restricted T cells.

1995 • 125 citations

pH sensitive liposomes provide an efficient means of sensitizing target cells to class I restricted CTL recognition of a soluble protein

1991 • 114 citations

Immortalized dendritic cell line fully competent in antigen presentation initiates primary T cell responses in vivo.

1993 • 108 citations

Immunoscintigraphy of prostatic cancer: Preliminary results with ¹¹¹in‐labeled monoclonal antibody 7E11‐C5.3 (CYT‐356)

1991 • 95 citations

Melanoma‐specific CD4+ T lymphocytes recognize human melanoma antigens processed and presented by epstein‐barr virus‐transformed B cells

1994 • 86 citations

New strategies for active immunotherapy with genetically engineered tumor cells

1992 • 66 citations

The ability of cultured Langerhans cells to process and present protein antigens is MHC-dependent.

1991 • 66 citations

Western blot assay for prostate‐specific membrane antigen in serum of prostate cancer patients

1994 • 58 citations

Comparison of prostate specific antigen, prostate specific membrane antigen, and LNCaP‐based enzyme‐linked immunosorbent assays in prostatic cancer patients and patients with benign prostatic enlargement

1995 • 51 citations

A new protocol for the propagation of dendritic cells from rat bone marrow using recombinant GM-CSF, and their quantification using the mAb OX-62

1995 • 50 citations

Immunoscintigraphy in patients with colorectal, ovarian, and prostate cancer. Results with site‐specific immunoconjugates

1993 • 43 citations

Systemic and Local Immunity in Allograft and Cancer Rejection

1978 • 39 citations

A rapid isolation procedure for dendritic cells from mouse spleen by centrifugal elutriation

1992 • 9 citations