Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Origin, maturation and antigen presenting function of dendritic cells

1997 • 1,375 citations

The immune system evolved to discriminate infectious nonself from noninfectious self

1992 • 1,324 citations

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

1998 • 1,226 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 1,041 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1992 • 763 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 694 citations

Localization, Quantitation, and In Situ Detection of Specific Peptide–MHC Class I Complexes Using a Monoclonal Antibody

1997 • 679 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

Constitutive class I-restricted exogenous presentation of self antigens in vivo.

1996 • 637 citations

Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo.

1993 • 487 citations

The Repertoire of T Cells Shaped by a Single MHC/Peptide Ligand

1996 • 417 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

1994 • 353 citations

Characterization of nonlymphoid cells derived from rat peripheral lymph

1983 • 343 citations

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes

1997 • 292 citations

Does T-cell tolerance require a dedicated antigen-presenting cell?

1989 • 288 citations

Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection.

1992 • 266 citations

On the complexity of self

1991 • 261 citations

Indirect recognition of donor HLA-DR peptides in organ allograft rejection.

1996 • 244 citations

A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.

1996 • 238 citations

Bone marrow-derived dendritic cells can process bacteria for MHC-I and MHC-II presentation to T cells.

1997 • 223 citations

Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides.

1992 • 218 citations

A novel MHC class II epitope expressed in thymic medulla but not cortex

1989 • 175 citations

Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody

1997 • 169 citations

Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins

1982 • 168 citations

Lymph‐Borne Dendritic Leucocytes do Not Recirculate, but Enter the Lymph Node Paracortex to Become Interdigitating Cells

1988 • 145 citations

Xenogeneic proliferation and lymphokine production are dependent on CD4+ helper T cells and self antigen-presenting cells in the mouse.

1990 • 141 citations

Antigen processing and presentation in transplantation

1996 • 140 citations

Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: An in vivo approach to investigate la gene function

1987 • 134 citations

Antigen-unspecific B Cells and Lymphoid Dendritic Cells Both Show Extensive Surface Expression of Processed Antigen–Major Histocompatibility Complex Class II Complexes after Soluble Protein Exposure In Vivo or In Vitro

1997 • 128 citations

Monoclonal antibody detection of a major self peptide. MHC class II complex.

1992 • 127 citations

Antigen presenting cells in the thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen

1997 • 109 citations

Dendritic cell maturation is required for initiation of the immune response

1997 • 98 citations

Antigen-presenting cells in the thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen.

1997 • 93 citations

Peripheral tolerance of CD4 T cells following local activation in adolescent mice

1996 • 82 citations

Organization of the transcriptional unit of a human class II histocompatibility antigen: HLA-DR heavy chain

1983 • 79 citations

Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains.

1991 • 52 citations

Mechanism of liver allograft rejection: The indirect recognition pathway

1997 • 46 citations

ISOLATION OF DENDRITIC CELLS IN THE RAT LIVER LYMPH

1995 • 44 citations

T cell recognition of self-human histocompatibility leukocyte antigens (HLA)-DR peptides in context of syngeneic HLA-DR molecules.

1992 • 41 citations