Mechanisms and Future Directions for Angiogenesis-Based Cancer Therapies

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Mechanisms of angiogenesis

1997 • 5,696 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Vascular-specific growth factors and blood vessel formation

2000 • 3,667 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

1997 • 3,470 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization

1999 • 3,280 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Antitumor Activity of Thalidomide in Refractory Multiple Myeloma

1999 • 2,565 citations

Thalidomide is an inhibitor of angiogenesis.

1994 • 2,460 citations

The microenvironment of the tumour–host interface

2001 • 2,307 citations

Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF

1999 • 2,176 citations

Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy

2001 • 2,069 citations

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

1998 • 2,040 citations

Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry

1999 • 1,921 citations

Regulation of Mammalian O₂Homeostasis by Hypoxia-Inducible Factor 1

1999 • 1,882 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Genes Expressed in Human Tumor Endothelium

2000 • 1,838 citations

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

1995 • 1,808 citations

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

1997 • 1,705 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

1995 • 1,608 citations

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

2000 • 1,536 citations

A common precursor for hematopoietic and endothelial cells

1998 • 1,433 citations

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

2000 • 1,372 citations

Transport of molecules in the tumor interstitium: a review.

1987 • 1,360 citations

Endothelial Apoptosis as the Primary Lesion Initiating Intestinal Radiation Damage in Mice

2001 • 1,245 citations

Organ targeting In vivo using phage display peptide libraries

1996 • 1,198 citations

Angiostatin induces and sustains dormancy of human primary tumors in mice

1996 • 1,193 citations

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.

1999 • 1,044 citations

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1999 • 1,019 citations

Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

1999 • 990 citations

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-analysis Group In Cancer.

1998 • 979 citations

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

1999 • 919 citations

Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.

1999 • 866 citations

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

2000 • 853 citations

Detection of tumor angiogenesis in vivo by αvβ3-targeted magnetic resonance imaging

1998 • 851 citations

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors.

1997 • 841 citations

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis.

1997 • 832 citations

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing

1999 • 830 citations

Matrix metalloproteinases in tumor invasion and metastasis

2000 • 820 citations

Development of Matrix Metalloproteinase Inhibitors in Cancer Therapy

2001 • 788 citations

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

1995 • 766 citations

New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF

1999 • 751 citations

Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.

2000 • 750 citations

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

1994 • 743 citations

Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development

1999 • 708 citations

flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors

1993 • 707 citations

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

1997 • 694 citations

Matrix metalloproteinases and metastasis

1999 • 688 citations

Combined effects of angiostatin and ionizing radiation in antitumour therapy

1998 • 679 citations

Vasculogenic Mimicry and Tumor Angiogenesis

2000 • 673 citations

Membrane protein secretases

1997 • 634 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Clinical Implications of Circulating Angiogenic Factors in Cancer Patients

2001 • 599 citations

Steps toward mapping the human vasculature by phage display

2002 • 591 citations

Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia.

1997 • 546 citations

Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis.

2001 • 545 citations

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

2000 • 545 citations

Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma

1991 • 523 citations

Angiostatin binds ATP synthase on the surface of human endothelial cells

1999 • 520 citations

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

1995 • 517 citations

A Role for Hematopoietic Stem Cells in Promoting Angiogenesis

2000 • 512 citations

Matrix metalloproteinase inhibitors

1997 • 509 citations

Suppression of tumor growth through disruption of hypoxia-inducible transcription

2000 • 501 citations

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

2000 • 501 citations

Cell Type-Specific Expression of Angiopoietin-1 and Angiopoietin-2 Suggests a Role in Glioblastoma Angiogenesis

1998 • 491 citations

Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny

1989 • 460 citations

Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

1998 • 455 citations

Molecular profiling of human cancer

2000 • 451 citations

Interaction of endostatin with integrins implicated in angiogenesis

2001 • 442 citations

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats.

1993 • 442 citations

Expression and functional significance of VE-cadherin in aggressive human melanoma cells: Role in vasculogenic mimicry

2001 • 440 citations

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

2000 • 435 citations

Angiostatin-converting Enzyme Activities of Human Matrilysin (MMP-7) and Gelatinase B/Type IV Collagenase (MMP-9)

1997 • 430 citations

Phase II Trial of the Antiangiogenic Agent Thalidomide in Patients With Recurrent High-Grade Gliomas

2000 • 428 citations

Effect of p53 Status on Tumor Response to Antiangiogenic Therapy

2002 • 427 citations

Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.

1997 • 415 citations

Redefining the Target: Chemotherapeutics as Antiangiogenics

2001 • 397 citations

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

1998 • 376 citations

Angiomotin

2001 • 372 citations

Continuous release of endostatin from microencapsulated engineered cells for tumor therapy

2001 • 372 citations

Phase Ib Trial of Intravenous Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor in Combination With Chemotherapy in Patients With Advanced Cancer: Pharmacologic and Long-Term Safety Data

2001 • 369 citations

Kringle Domains of Human Angiostatin

1996 • 366 citations

Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

2001 • 359 citations

Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting.

1999 • 354 citations

Control of Apoptosis during Angiogenesis by Survivin Expression in Endothelial Cells

2000 • 347 citations

Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer

2000 • 346 citations

Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor–positive human tumors

2001 • 343 citations

Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications.

1999 • 339 citations

The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors.

2001 • 333 citations

Angiogenesis: a Dynamic Balance of Stimulators and Inhibitors

1997 • 325 citations

The Hemostatic System as a Regulator of Angiogenesis

2000 • 322 citations

Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase.

2000 • 316 citations

Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis.

1998 • 311 citations

Cell Surface Glypicans Are Low-Affinity Endostatin Receptors

2001 • 310 citations

Local endostatin treatment of gliomas administered by microencapsulated producer cells

2001 • 303 citations

Activity of Thalidomide in AIDS-Related Kaposi’s Sarcoma

2000 • 293 citations

Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

2001 • 276 citations

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

2001 • 275 citations

Antiangiogenesis Is Produced by Nontoxic Doses of Vinblastine

1999 • 271 citations

Oxygen and the Growth and Development of Retinal Vessels

1966 • 264 citations

Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model.

2001 • 259 citations

Epidermal growth factor receptor biology (IMC-C225)

2001 • 253 citations

Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer.

1998 • 248 citations

Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine

2000 • 236 citations

Broad Antitumor and Antiangiogenic Activities of AG3340, a Potent and Selective MMP Inhibitor Undergoing Advanced Oncology Clinical Trials

1999 • 234 citations

PGH synthase isoenzyme selectivity: The potential for safer nonsteroidal antiinflammatory drugs

1993 • 228 citations

Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth.

2000 • 228 citations

In Situ Expression of Angiopoietins in Astrocytomas Identifies Angiopoietin-2 as an Early Marker of Tumor Angiogenesis

1999 • 222 citations

Preclinical and Clinical Studies of MMP Inhibitors in Cancer

1999 • 222 citations

Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system.

1996 • 217 citations

A High-Affinity Human Antibody That Targets Tumoral Blood Vessels

1999 • 209 citations

Antiangiogenic gene therapy

1998 • 201 citations

Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.

1998 • 201 citations

Specific Interaction of Angiostatin with Integrin αvβ3 in Endothelial Cells

2001 • 196 citations

New paradigms for the treatment of cancer: The role of anti-angiogenesis agents

2000 • 194 citations

Suppression of Vascular Endothelial Growth Factor-Mediated Endothelial Cell Protection by Survivin Targeting

2001 • 189 citations

Liposomes complexed to plasmids encoding angiostatin and endostatin inhibit breast cancer in nude mice.

1999 • 179 citations

Nonsteroidal anti-inflammatory drugs and colorectal cancer: Evolving concepts of their chemopreventive actions

1997 • 178 citations

Domain 5 of high molecular weight kininogen (kininostatin) down-regulates endothelial cell proliferation and migration and inhibits angiogenesis

2000 • 178 citations

Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA.

1998 • 173 citations

Tyrosine kinase inhibitors—ZD1839 (Iressa)

2001 • 171 citations

The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing

2000 • 170 citations

Phase I Clinical Trial of Oral COL-3, a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer

2001 • 155 citations

Targeting tumor vasculature with homing peptides from phage display

2000 • 154 citations

Establishing a Link between Oncogenes and Tumor Angiogenesis

1998 • 148 citations

Mechanism of action of angiostatic steroids: Suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis

1993 • 144 citations

Stable remission after administration of the receptor tyrosine kinase inhibitor SU5416 in a patient with refractory acute myeloid leukemia

2001 • 139 citations

Tumour vasculature as a target for anticancer therapy

2000 • 139 citations

Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2

2000 • 137 citations

Clinical trials of antiangiogenic drugs: opportunities, problems, and assessment of initial results.

2001 • 132 citations

Matrix metalloproteinase inhibitors: Present achievements and future prospects

1997 • 128 citations

Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras

1999 • 128 citations

Dose-Finding and Pharmacokinetic Study of Cisplatin, Gemcitabine, and SU5416 in Patients With Solid Tumors

2002 • 126 citations

Gene therapy strategies for tumor antiangiogenesis

1998 • 126 citations

Endothelial cells of tumor vessels: abnormal but not absent.

2000 • 126 citations

Clinical studies with matrix metalloproteinase inhibitors

1999 • 126 citations

Association of serum endoglin with metastasis in patients with colorectal, breast, and other solid tumors, and suppressive effect of chemotherapy on the serum endoglin.

2001 • 122 citations

Endostatin Binds Tropomyosin

2001 • 122 citations

Characterization of hematopoietic cells arising on the textured surface of left ventricular assist devices

1995 • 122 citations

Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy.

1998 • 119 citations

Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor

2001 • 117 citations

Combination Angiostatin and Endostatin Gene Transfer Induces Synergistic Antiangiogenic Activity in Vitro and Antitumor Efficacy in Leukemia and Solid Tumors in Mice

2001 • 116 citations

Neovastat, a naturally occurring multifunctional antiangiogenic drug, in phase III clinical trials

2001 • 115 citations

The presence and release of alpha 2-antiplasmin from human platelets

1981 • 114 citations

Matrix metalloproteinase inhibitors

1998 • 110 citations

The Angiogenesis Inhibitor, Endostatin, Does Not Affect Murine Cutaneous Wound Healing

2000 • 108 citations

Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells.

1999 • 107 citations

Tumor angiogenesis: Molecular pathology, therapeutic targeting, and imaging

2000 • 106 citations

Molecular biology of breast cancer metastasis Molecular expression of vascular markers by aggressive breast cancer cells

2000 • 104 citations

Angiozyme: A Novel angiogenesis inhibitor

2001 • 101 citations

Maintenance of Vascular Integrity in the Embryo Requires Signaling through the Fibroblast Growth Factor Receptor

2000 • 100 citations

Pilot study of vitaxin?an angiogenesis inhibitor?in patients with advanced leiomyosarcomas

2001 • 97 citations

Monoclonal antibody therapy of cancer.

1999 • 96 citations

Implementation of Intussusceptive Microvascular Growth in the Chicken Chorioallantoic Membrane (CAM):

1996 • 93 citations

Administration of a liposomal FGF-2 peptide vaccine leads to abrogation of FGF-2-mediated angiogenesis and tumor development

2000 • 89 citations

Promising new developments in cancer chemotherapy

1999 • 88 citations

Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human non-small cell lung cancer tumors: single agent and combination chemotherapy studies.

1999 • 88 citations

The role of circulating cells in the healing of vascular prostheses

1994 • 88 citations

Current role of thalidomide in cancer treatment

2000 • 83 citations

Immunochemical identification of human endothelial cells on the lining of a ventricular assist device.

1993 • 82 citations

Dominant effector genetics in mammalian cells

2001 • 81 citations

A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers.

2001 • 79 citations

Aquaporins and the respiratory system: advice for a lung investigator

2000 • 78 citations

Antiangiogenic radioimmunotherapy of human solid tumors in SCID mice using125I-labeled anti-endoglin monoclonal antibodies

1999 • 77 citations

Results of a Randomized Study of IM862 Nasal Solution in the Treatment of AIDS-Related Kaposi’s Sarcoma

2000 • 76 citations

Radioimmunotherapy of micrometastases in lung with vascular targeted213Bi

1999 • 71 citations

Intramuscular electroporation delivery of IFN-α gene therapy for inhibition of tumor growth located at a distant site

2001 • 67 citations

Dual Origin of Intimal Cells in Cardiac-Allograft Arteriosclerosis

1971 • 66 citations

Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model

2000 • 62 citations

Platelet alpha2-macroglobulin and alpha1-antitrypsin.

1976 • 58 citations

Anti-angiogenic treatment strategies for malignant brain tumors.

2000 • 58 citations

Neovascular Targeting with Cyclic RGD Peptide (cRGDf-ACHA) to Enhance Delivery of Radioimmunotherapy

2000 • 56 citations

Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy

2001 • 54 citations

Angiogenesis inhibitors in the treatment of lung cancer

2001 • 53 citations

Fas-Mediated Apoptosis in Ewing's Sarcoma Cell Lines by Metalloproteinase Inhibitors

1999 • 53 citations

Effect of Retroviral Endostatin Gene Transfer on Subcutaneous and Intraperitoneal Growth of Murine Tumors

2001 • 52 citations

Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo

1998 • 51 citations

Liposome-delivered angiostatin strongly inhibits tumor growth and metastatization in a transgenic model of spontaneous breast cancer.

2000 • 50 citations

Human Prothrombin Fragment 1 and 2 Inhibit bFGF-Induced BCE Cell Growth

1998 • 45 citations

Novel therapeutic agents for the treatment of myelodysplastic syndromes.

2000 • 44 citations

Angiogenesis and antiangiogenic approaches to sarcomas

2001 • 44 citations

Matrix Metalloproteinase Inhibitor COL-3 in the Treatment of AIDS-Related Kaposi’s Sarcoma: A Phase I AIDS Malignancy Consortium Study

2002 • 44 citations

Clinical relevance of Flt1 and Tie1 angiogenesis receptors expression in B-cell chronic lymphocytic leukemia (CLL)

2001 • 40 citations

Thalidomide in the treatment of cancer

2000 • 37 citations

Extracellular matrix inhibits apoptosis and enhances endothelial cell differentiation by a NF?B-dependent mechanism

1999 • 35 citations

Angiogenesis-directed implantation of genetically modified endothelial cells in mice.

1995 • 34 citations

Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.

2000 • 33 citations

Statin-AE: a novel angiostatin-endostatin fusion protein with enhanced antiangiogenic and antitumor activity.

2001 • 32 citations

Inhibition of matrix metalloproteinases by over‐expression of tissue inhibitor of metalloproteinase‐2 inhibits the growth of experimental hemangiomas

2001 • 31 citations

Selective modulation of collagenase 1 gene expression by the chemotherapeutic agent doxorubicin.

1999 • 29 citations

Regulation of Tumor Angiogenesis by Organ-Specific Cytokines

1996 • 26 citations

The Role of the Pericellular Fibrinolytic System in Angiogenesis.

1997 • 24 citations

New molecular targets and biological therapies in sarcomas

2001 • 21 citations

HL-60 leukemia cells produce an autocatalytically truncated form of matrix metalloproteinase-9 with impaired sensitivity to inhibition by tissue inhibitors of metalloproteinases.

1996 • 20 citations

Phase I and pharmacokinetic study of a micronized formulation of carboxyamidotriazole, a calcium signal transduction inhibitor: toxicity, bioavailability and the effect of food.

2002 • 20 citations

Retroviral vector-producer cell mediated angiogenesis inhibition restricts neuroblastoma growth in vivo

2000 • 18 citations

Dose-dense therapy with paclitaxel via weekly 1-hour infusion: preliminary experience in the treatment of metastatic breast cancer.

1997 • 18 citations

IL-12-induced production of IL-10 and interferon-γ by mononuclear cells in lung cancer-associated malignant pleural effusions

2002 • 16 citations

9:30—9:45 First Pass FDG Measured Blood Flow in Tumors: A Comparison with O-15 Labeled Water Measured Blood Flow

2000 • 15 citations

Hyperthermic isolated limb perfusion with tumour necrosis factor and melphalan as treatment of locally advanced or recurrent soft tissue sarcomas of the extremities

1998 • 13 citations

The presence and release of alpha 2-antiplasmin from human platelets

1981 • 8 citations

Bioimmunotherapeutic targets on angiogenetic blood vessels in solid malignangies

2001 • 3 citations